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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Targeted Inactivation of the CCR5 HIV Coreceptor with Peptide Nucleic Acids
SBC: L2 DIAGNOSTICS LLC Topic: NIAIDDESCRIPTION (provided by applicant): Over 34 million people are currently living with HIV/AIDS. Combination antiviral therapies have significantly reduced the morbidity and mortality of the disease; however, there is currently no cure for the disease. Discovery that a naturally occurring variant of CCR5, the delta32 mutation, renders cells resistant to HIV infection has led to efforts by several a ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Formulation of LbL microparticle vaccine in microneedle array for intradermal del
SBC: ARTIFICIAL CELL TECHNOLOGIES INC Topic: NIAIDAbstract The ability of the immune system to recognize and initiate an immune response to foreign particles such as bacteria and viruses has generated interest in development of particulate vaccine technologies. We are developing an innovative approach toproduce particulate vaccines via layer-by-layer (LbL) fabrication of synthetic microparticles (MP). We have shown that LbL-MP loaded with epitope ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
A Quantum Similarity Approach for the Discovery of Anti-Trypanosome Drug Leads
SBC: GRADIENT BIOMODELING, LLC Topic: NIAIDDESCRIPTION (provided by applicant): Human African trypanosomiasis (HAT) is an infectious disease with a large global health burden occurring primarily in Central and Eastern Africa. HAT is 100% fatal if untreated and the current drug therapies suffer frompoor safety profiles, difficult treatment regimens, limited effectiveness, and high costs. Furthermore, drugs that cross the blood brain barrier ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Multiplexed Ovarian Cancer Microfluidic Tissue Microarray
SBC: Carterra, Inc. Topic: NCIProject Summary We propose an instrument system for automated, multiplexed cell- and tissue-based experiments (i.e. tissue microarrays) called the Microfluidic Flow Cell Array (MFCA). The MFCA consists of a microfluidic flow cell array integrated with an inverted fluorescent microscope, allowing the observation of 48 flow chambers simultaneously or an individual chamber at higher magnification. Th ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
The Development of Novel Inhibitors of BCL2 Gene Expression as Anticancer Therape
SBC: TETRAGENE, LLC Topic: NCIProject Summary Evasion of apoptosis is a hallmark of cancer and is associated with oncogenesis, tumor maintenance, and resistance to conventional chemotherapy. BCL-2 was the first identified anti-apoptotic factor and is a member of the BCL-2 family of proteins that cooperate in the regulation of programmed cell death. BCL-2 plays a dominant role in the survival of multiple lymphoid malignancies a ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Immune-based brain cancer diagnostic for rapid, accurate disease classification
SBC: HealthTell Inc. Topic: NCIDESCRIPTION (provided by applicant): Accurate, early disease diagnosis and monitoring are critical aspects to effective prevention, treatment, and remission of disease. Most diagnostic methods available today are not simple or sensitive enough to significantly impact patients' response to treatment or survival outcome. This unmet need is highlighted by diseases, such as brain cancers, that o ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Development of a 3-D multi-planar biopsy system using new ultrasound tomographic
SBC: Delphinus Medical Technologies, Inc Topic: NCIPROJECT SUMMARY Biopsy capability is an absolute requirement for imaging facilities planning to provide breast cancer screening services. The limitations of mammography have ushered in several other imaging technologies, such as magnetic resonance (MR), positron emission mammography, and breast specific gamma, or molecular breast imaging. However, these are all relatively expensive modalities and ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Targeting ether lipid biosynthesis for disease
SBC: ECHELON BIOSCIENCES, INC. Topic: NCIDESCRIPTION (provided by applicant): Cancer is a significant health burden in the US and across the globe, representing the second leading cause of death in the US. Cancer cells have metabolic pathways that are altered significantly compared to normal cells. As a result, the pathways involved (lipid biosynthesis for example) are considered excellent targets for therapeutic intervention. The levels ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Using Technology to Improve Clinical Counseling of Adolescent Risky Behaviors
SBC: POSSIBILITIES FOR CHANGE LLC Topic: NIDADESCRIPTION (provided by applicant): The goal of this SBIR is to develop an innovative adolescent primary health care delivery model for use in primary care that overcomes barriers of health care provider time, skill and teen engagement when providing effective tobacco use reduction counseling. This will be achieved by creating a web-based counseling module that will provide interactive, technolog ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Microfabricated Cochlear Electrode Arrays
SBC: MEMStim LLC Topic: NIDCDDESCRIPTION (provided by applicant): In the USA, about 36 million adults suffer from hearing loss and three out of every 1,000 children are born deaf or hard-of-hearing. When conventional hearing aids provide no appreciable benefit, implantable electronicdevices using electrode arrays inside the cochlea are a viable solution. With these cochlear implants, the profoundly deaf achieve reasonable wor ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health