You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Completion of IND-package for a novel, non-narcotic painkiller

    SBC: Blue Therapeutics Inc            Topic: NIDA

    Project Summary Opioids like morphine and hydrocodone are generally the most effective therapeutics for treatment of moderate to severe painHowevertheir use is limited by serious side effectstoleranceconstipationrespiratory depressionphysical dependence and high addictive potentialThe frequency of clinical paincoupled with a lack of alternative therapeutic options has led to a national health cris ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Developing a robust and scalable calibration approach to low-cost AQ sensing

    SBC: Aerodyne Research, Inc.            Topic: 813

    Poor air quality represents a major public health risk, contributing to an estimated one of every eight deaths worldwide. Low-cost air quality sensors have developed rapidly over the last few years and offer the opportunity to make air quality monitoring widespread at an affordable price. However, low-cost sensors are currently unable to deliver accurate, reliable data due to a lack of understandi ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  3. OpenORB Low-Cost Mooring Location Beacon for Costal Applications

    SBC: Triton Systems, Inc.            Topic: 825

    Triton Systems, Inc. proposes development of the Open-Source Oceanographic Asset Recovery Beacon (OpenORB) that will allow the deployment of coastal instrumentation moorings with affordable protection against loss. This open-source kit would significantly reduce the purchase price of a commercial location beacon by allowing the end-user to assemble a customized system with minimal time and effort. ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  4. Phase II Commercialization of HABStats: A Harmful Algal Bloom Species, Toxin and Total Phytoplankton Identification System

    SBC: CoastalOceanVision, Inc            Topic: 821

    In Phase I, we developed a prototype instrument for counting, sizing and identifying both non-toxic and toxic Harmful Algal Bloom (HAB) species. We did this by integrating three innovative technologies: High-throughput color, Light Field Imaging Flow Cytometry to acquire morphological information for each cell, Raman spectroscopy to acquire species-specific molecular information on pigments and tr ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  5. SBIR TOPIC 104, FAST-TRACK, TAPERED GUIDEWIRES FOR TRANSCATHETER ELECTROSURGERY

    SBC: TRANSMURAL SYSTEMS LLC            Topic: NHLBI

    The contractor will develop specific guidewire devices to ease and simplify transcaval access to the aortato make the procedure available to a wider range of patients and operatorsThe goal is to develop a tapered guidewire and a connector switch to a common electrosurgery generator to simplify transcaval access to the aortaUnder Phase I the contractor will develop and test a suite of working proto ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. SBIR PHASE II: LABHAND PAYLOAD FOR INSTANTEYE SUAS PLATFORM FOR CONTINUOUS AUTONOMOUS INDOOR TRANSPORT OF LABORATORY CONSUMABLES

    SBC: Physical Sciences Inc.            Topic: NIDA

    The objective of this Phase II SBIR contract and subsequent Phase III effort is to develop and commercialize acompleteautonomous drone based system for moving microplatesand similar lab consumableswithin HighThroughput ScreeningHTSlaboratoriessupplementing and perhaps eventually replacing robotic arms whichcurrently perform HTS autonomous processing of samplesThis innovative application of smallau ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. SBIR PHASE II TOPIC 294:SITE-SPECIFIC ANTIBODIES FOR GLCNACYLATED PROTEINS IN CANCER; HHSN261201300058C; POP: 9/13/13-09/12/16; CAN: 8478363 IGF::OT::IGF OTHER FUNCTIONS

    SBC: DETROIT R & D, INC.            Topic: NCI

    O GlcNAcylation of proteins plays a critical role in cell cycle regulationapoptosis and signal transductionModification of O GlcNAcylation of proteins by O GlcNAc transferase is reversible by the activity of O GlcNAcaseAddition and removal of O GlcNAc moiety to serine or threonine regulate the function of proteins directly or via decreased phosphorylationO GlcNAcylation of c myc proteins induces u ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. TOPIC 366: I-PARTS INTEGRATED PLATFORM FOR ANTI-CANCER RADIATION THERAPEUTICS SCREENING

    SBC: PACT & HEALTH LLC            Topic: NCI

    Tumor Irradiation during cancer treatment induces clonogenic death that can be best assessed by colony forming assaysThese colony forming assays are laborious and never utilized in high throughput screeningHTSformatsWe propose to develop anintegrated platform for HTS clonogenic survival assayfor cancer drug screening as well as radiation effect modulation screeningNamedI PARTSIntegrated platform f ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Measuring toxicant effects on cellular function in a microarray format

    SBC: CIENCIA INC            Topic: 113

    Project Summary AbstractThe EPA maintains a Toxics Release Inventory of andgttoxic chemicals that are disposed or released from andgtindustrial sites in the United Stateswhile HHS and USDA maintain a list of overselect agents and toxicants that pose a severe risk to humananimaland plant healthThese compounds represent only a fraction of the known and unknown environmental toxicants that may advers ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Precise Minimally InvasiveTreatment of VT Using Non-invasive Mapping.

    SBC: HEARTLANDER SURGICAL, INC.            Topic: NHLBI

    Project Summary Ventricular TachycardiaVTis a major public health problem associated with the majority of thecases of sudden cardiac death in the United States each yearThe best current therapy for VT involves drugs to reduce VT episodes plus implantation of a cardiac defibrilatorICDthat prolongs life by terminating episodes of VTPermanent cessation of VT can be achieved by ablation of the origin ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government