Award Data

TECHNICAL ABSTRACT: Recent advances in gas chromatographic (GC) and mass spectrometric (MS) techniques for atmospheric measurements have led to highly complex data sets that have overwhelmed the capabilities of current data analysis software. We propose a new method for the automated reduction of chromatographic data using peak-fitting algorithms. By relying upon constrained peak-fit parameterizat ...

TECHNICAL ABSTRACT: We propose to continue the development of a generalized 3DVAR data assimilation module, in an open-source and non-proprietary programming language, which is compatible with FVCOM and incorporated into the Lake Erie Operational Forecast System (LEOFS). We will leverage our experience and expertise in using 3DVAR for a ROMS-based real-time forecast system for the California coast ...

TECHNICAL ABSTRACT: The Hybrid Quadrotor concept, developed by Latitude Engineering, combines the high power density of electric motors and propellers with the high energy density of a piston engine and liquid fuel. Together, each technology enables maximum performance in HQ's two regimes of flight: the electric system is responsible for lift while hovering (high power, short endurance), and the g ...

TECHNICAL ABSTRACT: Tropospheric oxidation capacity is dominated by HOx photochemistry, however halogen atoms and oxides significantly affect these chemical cycles. A sensitive and robust measurement of gaseous HCl is critically important to improve our understanding of halogen chemistry and its impacts on the spatial and temporal oxidation capacity of the atmosphere. In Phase I, we met all of our ...

Cancer survivors commonly report cognitive impairments following chemotherapy. With a growing number of cancer survivors comes an increased urgency to better understand the precise etiology and prevalence of cognitive changes associated with cancer and cancer treatment. This pursuit is impeded by a lack of assessment tools that can accurately detect the full scope of cognitive deficits. To address ...

The goal of this fast track STTR proposal is to expand buprenorphine maintenance therapy for opioiddependent patientsOvermillion people in the US are addicted to opiatesProviding effective agonist therapymethadone or buprenorphinecoupled with behavioral counseling greatly improves outcomesreduces morbidityand reduces societal costsMethadone maintenance treatment has been limited due to complex sta ...

PROJECT SUMMARY In response to the growing need for training on interventions to address first episode psychosis, the Center for Social Innovation (C4) has partnered with experts in Coordinated Specialty Care (CSC) to develop and test CSC OnDemand: An Innovative Online Learning Platform for Implementing Coordinated Specialty Care. The product builds on the findings of the Recovery After an Initial ...

Approximatelymillion Americans suffer from asthmawhich leads to aboutdeaths per yearand is responsible for estimated annual total direct and indirect costs of $billionDespite the existing treatments for asthmapredominantly combinations of inhaledagonists and corticosteroidsCSsthere remains a significant unmet medical need for new therapies which address two key issuesapproximatelyof patients are i ...

PROJECT SUMMARYStroke is a major public health problem in the U Sand worldwideIt is defined as an area of brain damagegenerally due to the sudden occlusion of an artery in or leading to the brainStroke can cause weaknessnumbnessvisual disturbancespeech difficultybalance problemsand memory lossamong other symptomsWhile good treatments exist to limit stroke in the first few hours after occurrencefew ...

Recent advances in DNA sequencing technology have not been matched by improved analytic techniques to quickly and accurately interpret patient genome data to inform diagnosisprognosis and therapy making decisions in the clinic and to identify candidate biomarkers of disease in research laboratoriesDevelopment of automated techniques to facilitate interpretation of this data will benefit patient ca ...