List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Developing a robust and scalable calibration approach to low-cost AQ sensing

    SBC: Aerodyne Research, Inc.            Topic: 813

    Poor air quality represents a major public health risk, contributing to an estimated one of every eight deaths worldwide. Low-cost air quality sensors have developed rapidly over the last few years and offer the opportunity to make air quality monitoring widespread at an affordable price. However, low-cost sensors are currently unable to deliver accurate, reliable data due to a lack of understandi ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  2. OpenORB Low-Cost Mooring Location Beacon for Costal Applications

    SBC: Triton Systems, Inc.            Topic: 825

    Triton Systems, Inc. proposes development of the Open-Source Oceanographic Asset Recovery Beacon (OpenORB) that will allow the deployment of coastal instrumentation moorings with affordable protection against loss. This open-source kit would significantly reduce the purchase price of a commercial location beacon by allowing the end-user to assemble a customized system with minimal time and effort. ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  3. Phase II Commercialization of HABStats: A Harmful Algal Bloom Species, Toxin and Total Phytoplankton Identification System

    SBC: CoastalOceanVision, Inc            Topic: 821

    In Phase I, we developed a prototype instrument for counting, sizing and identifying both non-toxic and toxic Harmful Algal Bloom (HAB) species. We did this by integrating three innovative technologies: High-throughput color, Light Field Imaging Flow Cytometry to acquire morphological information for each cell, Raman spectroscopy to acquire species-specific molecular information on pigments and tr ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  4. DEVELOPMENT OF NOVEL PDE4B INHIBITORS TO TREAT ALCOHOL USE DISORDER (SBIR PHASE II)

    SBC: CODEX BIOSOLUTIONS            Topic: NIAAA

    Development of Novel PDE B Inhibitors to Treat Alcohol Use Disorder

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. SBIR TOPIC 108, FAST-TRACK- DEVICE SYSTEM FOR TRANSCATHETER REPAIR OF POSTINFARCTION VENTRICULAR SEPTAL DEFECT

    SBC: TRANSMURAL SYSTEMS LLC            Topic: NHLBI

    The goal of the project is to develop a device for percutaneous closure of postinfarction ventricular septal defectVSDin adultsFirst a prototype would be developed and tested in animalsand ultimately a clinical grade device would undergo regulatory developmentPhase I will include the development and testing of a postinfarction VSD occluder prototypePhase II will include mechanical and safety testi ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. SBIR TOPIC 106, FAST-TRACK- ACTIVE MRI NEEDLE

    SBC: TRANSMURAL SYSTEMS LLC            Topic: NHLBI

    Needle access to deep organs is common to numerous catheterradiologicaland surgical proceduresboth diagnostic and therapeuticincluding access to blood vesselspericardial and cardiac chambersvisceraetcMRI operation affords exquisite imaging and delineation of soft tissue beyond what is afforded by X ray fluoroscopyCTand ultrasound guidancePassiveneedles visualized solely by their material propertie ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. SBIR TOPIC 104, FAST-TRACK, TAPERED GUIDEWIRES FOR TRANSCATHETER ELECTROSURGERY

    SBC: TRANSMURAL SYSTEMS LLC            Topic: NHLBI

    The contractor will develop specific guidewire devices to ease and simplify transcaval access to the aortato make the procedure available to a wider range of patients and operatorsThe goal is to develop a tapered guidewire and a connector switch to a common electrosurgery generator to simplify transcaval access to the aortaUnder Phase I the contractor will develop and test a suite of working proto ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. SBIR TOPIC 107, PHASE I- TRANSCATHETER POTTS SHUNT

    SBC: TRANSMURAL SYSTEMS LLC            Topic: NHLBI

    The goal of Phase I is to develop and test a Transcatheter Potts Shunt prototype system in vivoThe deliverable is a catheter system to establish a non surgical Potts Shunttranscatheter pulmonary to aortic anastomosisto treat refractory pulmonary artery hypertensionPhase I will focus on mechanical and biological performance of the proposed endografttaking into account mechanical strength required f ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Nanoparticle Delivery of HIV Env Trimer for Inducing Somatic Hypermutation and bNAb

    SBC: Anatagen Pharmaceuticals, Inc.            Topic: NIAID

    HIVthe virus that causes AIDSis one of the world s most serious health challengesAccording to UNAIDSthere were approximatelymillion people worldwide living with HIV AIDS at the end ofThe vast majority of them are in lowto middle income countriesparticularly in sub Saharan AfricaA low cost vaccine broadly neutralizing most strains of HIV is the preferred response to protect the human populationHowe ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Antibody Fragments to Improve HIV gp120 Protein Production

    SBC: Abzyme Therapeutics, LLC            Topic: NIAID

    Camelid single domain antibody fragmentsVHHpossess a number of distinctive features including a small sizean elevated stabilityand an ability to recognize epitopes non accessible for conventional antibodiesBesides common research and immunotherapy applicationscamelid VHHs are also used as co crystallization chaperonesprotein aggregation controllers and enzyme activity tunersIn this proposalwe wish ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government