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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Broad Spectrum Antiviral Nucleoside Phosphonate Analogs

    SBC: TSRL, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The Working Group for Civilian Biodefense reviewed potential biological threat agents and listed those considered to pose the greatest threat to the civilian population Variola and other orthopox DNA viruses were identified as a potential bioterrorism threat Additionally other DNA viruses are of increasing concern in a public health context due to the emerge ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Protease resistant D peptide Inhibitors of Ebola Virus Entry

    SBC: NAVIGEN, INC.            Topic: R

    DESCRIPTION provided by applicant Ebola virus causes highly lethal hemorrhagic fever in humans and non human primates Since the first outbreak in there have been over natural human outbreaks with an average mortality rate near There are no approved agents to prevent or treat Ebola infection Due to ease of dissemination high lethality and ability to cause widespread panic the ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Commercialization of a Simple Automatic Perfusion System for ECPR

    SBC: MICHIGAN CRITICAL CARE CONSULTANTS, INC.            Topic: NHLBI

    DESCRIPTIONprovided by applicantThe use of ECMO in conjunction with CPRa technique known as "ECPR"has been shown to reduce central nervous systemCNSdamageimprove brain function after recoveryand result in survival to hospitaldischarge rates up toA limiting factor for widespread adoption of ECPR is the need for a simple automatic perfusion system that is inherently safeand provides full support wit ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. SYSTEMIC RADIONUCLIDE THERAPY TARGETED TO VEGF RECEPTORS IN TUMOR VASCULATURE

    SBC: SIBTECH, INC.            Topic: NCI

    The overall goal of this collaborative project between SibTech Inc PI Backer J and Johns Hopkins University PI Pomper M is clinical development of efficient and cost effective anti angiogenic Lu radiopharmaceutical scV Lu for VEGF receptor mediated targeting of angiogenic tumor vasculature Current very expensive anti angiogenic compounds induce transient regression of tumor vascula ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Implementing the Daylight Object Restoration Algorithm for Imaging in Daylight and Strong Turbulence

    SBC: HART SCIENTIFIC CONSULTING INTERNATIONAL L.L.C.            Topic: AF103017

    ABSTRACT:A new algorithm, the Daylight Object Restoration Algorithm (DORA), has been developed. DORA includes a novel implementation of the multi-frame blind deconvolution image restoration concept which recovers high-quality object estimates from sequences of degraded images. DORA removes the effects of atmospheric aberration in images recorded at ground-based telescopes, and is designed to opera ...

    SBIR Phase II 2015 Department of DefenseAir Force
  6. Antifungal therapy against drug resistant fungal pathogens.

    SBC: LIFEPHARMS, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Despite medical advances fungal infections still exact a heavy burden on the HIV AIDs population AIDs related fungal infections account for of all AIDs related deaths In the developed world AIDS related fungal infections are most frequently associated with Candida albicans but Aspergillus fumigatus and Cryptococcus neoformans are also common Unfortunat ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Holographic Video Display Using Novel Guided-wave Scanning System

    SBC: TIPD LLC            Topic: AF131023

    ABSTRACT:Todays analysts need improved 3D visualization tools to assist in critical situations such as deconfliction, line-of-sight analysis, air space and satellite control.Currently available 3D displays cannot provide the level of detail and comfort needed because the displays contain unacceptable visual artifacts, do not provide full parallax, require special headgear, and induce nausea in man ...

    SBIR Phase II 2015 Department of DefenseAir Force
  8. Development of DT-110 as an oral therapeutic for type 2 diabetes

    SBC: Diapin Therapeutics LLC            Topic: 200

    DESCRIPTION provided by applicant Type diabetes is a chronic debilitating disease that threatens to reach pandemic level by Nearly million people worldwide are currently affected by diabetes and more than of patients with type diabetes die of cardiovascular causes However no particular diabetes medication to date is considered superior in the minimization of the risk of card ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  9. A NOVEL TARGETED DELIVERY SYSTEM FOR CANCER TREATMENT AND DIAGNOSIS

    SBC: ENDURX PHARMACEUTICALS INC            Topic: 102

    DESCRIPTION provided by applicant Glioblastoma multiforme GBM or andquot glioblastoma andquot is the most common and aggressive malignant primary brain tumor in humans An effective treatment that increases patient survival would represent a significant advance in the field and provide a desperately needed new therapy for this deadly disease EnduRx is focused on the development of new tar ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Distributed Mission Operations Gateway

    SBC: SONALYSTS INC            Topic: AF141026

    ABSTRACT:The ultimate goal of this SBIR is to provide the Air Force and more specifically, the Distributed Mission OperationsSpace (DMO-S) community, with a way to connect the DMO Network to multiple AFSPC simulated operational environments to support DMO-S exercise activities.Sonalysts plans to develop a DMO to Standard Space Trainer (SST) Gateway to integrate each SST plug-in to support DMO-S gl ...

    SBIR Phase II 2015 Department of DefenseAir Force
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