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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A universal eye drop adherence monitor to measure and improve adherence to ocular medications

    SBC: Universal Adherence LLC            Topic: N

    Project Summary Abstract Universal Adherence is an emerging medical device company dedicated to improving adherence to ocular medications through innovative technical solutionsOur proposed Devers Drop DeviceDwill accurately track when a patient removes an eye drop bottle capcommunicate usage data wirelessly to a database that researchers can accessand send alerts to patients when a medication is d ...

    STTR Phase I 2018 Department of Health and Human Services
  2. Development of a Yellow Fever Vaccine for a Vulnerable Population


    ABSTRACT Yellow fever virusYFVrepresents a mosquito borne emerging re emerging human pathogen that causesmortality and is endemic in andgtcountriesThe current live attenuated YFV vaccine was developed inand following the establishment of a virus seed lot systemit has not been modified or otherwise improved in overyearsAccording to the CDCthis vaccine causesserious adverse eventsSAEper million vacc ...

    SBIR Phase II 2018 Department of Health and Human Services
  3. Advancing Human Health by Lowering Barriers to Electrophysiology in Genetic Model Organisms

    SBC: NEMAMETRIX, INC            Topic: 300

    Project Summary The nematode worm Caenorhabditis elegans has proven valuable as a model for many high impact medical conditionsThe strength of Celegans derives from the extensive homologies between human and nematode genesand the many powerful tools available to manipulate genes in Celegansincluding expressing human genesResearchers utilizing medical models based on Celegans have converged on two ...

    SBIR Phase II 2018 Department of Health and Human Services
  4. Factor XI inhibitor for thrombosis

    SBC: Aronora, Inc            Topic: NHLBI

    Project Summary Although potent antithrombotic agents are availableall of these drugs inadvertently target vital hemostatic molecular mechanismsresulting in dose limiting hemorrhagic toxicity that restrict their useDue to a lack of safe thromboprophylaxisthrombotic blood vessel occlusions continue to be extremely prevalentand result in a wide range of severe disease conditions that remain the lead ...

    SBIR Phase II 2018 Department of Health and Human Services
  5. Mobility Rehab: A Biofeedback System for Mobility Rehabilitation for Older Adults

    SBC: APDM, INC.            Topic: NIA

    Project Summary Mobility limitations including gait and balance impairments are common in older adultsespecially those with neurological de citsGait and balance impairments are a major cause of falls and reduced quality of lifeAlthough laboratory studies show that biofeedback during exercise training can improve motor performancephysical therapists do not have access to an overground gait biofeedb ...

    SBIR Phase II 2018 Department of Health and Human Services
  6. HLS-Affordable, quantitative microchip-electrophoresis for sickle cell disease screening

    SBC: Hemex Health, Inc.            Topic: NHLBI

    PROJECT SUMMARY Sickle Cell DiseaseSCDaffectsAmericans and more thanmillion people globallyprimarily in economically disadvantaged populationsIt is estimated that nearlyof children born with SCD in these areas die before the age of fivealthoughcould be saved through simplecost effective treatments if diagnosed early according to World Health OrganizationEarly diagnosis of SCD remains a challenge i ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. NeuroPredict, A screening assay for chemicals that affect the differentiation of human neural cells.

    SBC: Nzumbe, Inc.            Topic: NIEHS

    ABSTRACT A growing human health concern is that exposure to chemicals in our environment harms the highly vulnerable period of human brain developmentIndeedincreasing evidence shows that even simpleacute exposures of the developing brain to select agents cause profound neurological disorders such as epilepsyautism and intellectual disabilityDespite this vulnerabilitythe reliablehigh throughput ide ...

    SBIR Phase II 2018 Department of Health and Human Services
  8. Protect Yourself! Abuse Prevention for People with Intellectual Disabilities


    PROJECT SUMMARYIndividuals with intellectual disabilitiesIDare at higher risk for abuse than the general populationIncreasing numbers of people with ID are living independently in the community with both its benefits and its risksMany individuals with ID are subjected to physicalsexualand verbal abuseSome of the characteristics found in people with IDshort attention spandifficulties with abstract ...

    SBIR Phase II 2018 Department of Health and Human Services
  9. Expanding the Click City: Tobacco Prevention Program to Include E-cigarettes and Other Novel Tobacco Products

    SBC: Oregon Research Behavioral Intervention Strategies, INC            Topic: NIDA

    While the prevalence of smoking has decreased among youththe prevalence of e cigarettee ciguse has recently increased dramaticallygreatly exceeding that of cigarette useThe increased prevalence of ecig use among youththe health effects of e cigsand the increased probability that adolescents will become addicted to nicotine through the use of e cigs provide support for the crucial need for the inco ...

    SBIR Phase II 2018 Department of Health and Human Services
  10. Enabling electron-induced fragmentation in tandem mass spectrometry

    SBC: E-Msion, Inc.            Topic: 400

    The primary market focus for the high end mass spectrometer industry is to fully characterize proteins and their post translational modificationsPTMswithin the biopharmaceutical industryThese analyses remain challenging despite major advances in the speedresolution and mass accuracy of modern mass spectrometersA key weakness with current instrumentation for protein characterization lies in the met ...

    SBIR Phase II 2018 Department of Health and Human Services

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