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The use of biotin labeled ligands in receptor binding assays will be used as a substitute for radioHigh affinity biotinylated ligands are used in immunochemistry studies but are not generally employebinding experiments. Biotinylated ligands also have high affinities for the proteins avidin and streproteins can be coupled with various enzymes which catalyze spectrophotometric, fluorometric, or ched ...

The Phase I Project will develop a comprehensive model to evaluate and optimize state-of-the-art light-emitting diodes for optical memories, optical computing, and fiber or free-space photonic interconnects. The innovation is the development of resonant optical cavity LEDs and a proprietary low-cost epitaxy technology for their fabrication. A unified approach to the design of LEDs with resonant op ...

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There is an increasing awareness about the problems associated with blood transfusions. One concernbacterial contamination of blood bags. If contaminated blood is transfused, the person receiving thebecoming sick and dying. Current standards require that blood be visually inspected before leaving tblood has an abnormal appearance, it is not used. This visual quality check is subject to human judgt ...

The objective of this research program is to demonstrate the feasibility of a new controlled-releasuse in an injectable formulation of buprenorphine to improve treatment of opioid dependence. The keytechnology is the use of bioerodible microporous microbeads with a controllable structure that allowas well as easily varied release rates and durations of release. These controlled-release microbeadsi ...

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