List

In-situ measurement of meteorological, atmospheric chemistry, and oceanic parameters for regional models would aid greatly in the understanding of critical processes and provide the necessary data for national policy decisions on significant environmental issues. three Dimensional Reinforced (3DR) membranes have the ability to offer a dramatic reduction in the required envelope mass for balloons d ...

In-situ measurement of meteorological, atmospheric chemistry, and oceanic parameters for regional models would aid greatly in the understanding of critical processes and provide the necessary data for national policy decisions on significant environmental issues. three Dimensional Reinforced (3DR) membranes have the ability to offer a dramatic reduction in the required envelope mass for balloons d ...

Collagen based biosynthetic materials have profoundly improved the outcome of reconstruction and restoration of congenital defects and traumatic injuries. This has been most apparent for massive burn victims that historically suffered lifelong severe scarring and lost of function following wound closure before the advent of these materials. Unfortunately the failure rate for biosynthetic implants ...

Dose-response, enzyme kinetics, and other data in the biosciences are often modeled using non-linear least-squares curve-fitting algorithms. These methods are adversely impacted both by outliers and a non- Gaussian error distribution. Misleading confidence intervals on crucial parameters can result. This proposal describes preliminary non-linear optimization technology in the areas of robust fitti ...

DESCRIPTION (provided by applicant): Cayuse, Inc., has previously developed software (GrantSlam) which is used by thousands of investigators to create their paper-based NIH grant proposals. In so doing, they are simultaneously collecting data for ERA submission of their applications. The current version of GrantSlam has the solid beginnings of an ERA solution and Cayuse wants very much to extend i ...

The use of tobacco represents a significant public health problem, with specific effects on oral tissue. These effects provide dental health care workers (DHCWs) to help patients quit, yet, the majority of dental professionals cite lack of training as a barrier to providing these services. There is a need for disseminable, empirically-validated tobacco education. Interactive computer-based progr ...

The use of tobacco represents a significant public health problem, with specific effects on oral tissue. These effects provide dental health care workers (DHCWs) to help patients quit, yet, the majority of dental professionals cite lack of training as a barrier to providing these services. There is a need for disseminable, empirically-validated tobacco education. Interactive computer-based progr ...

DESCRIPTION (provided by applicant): The proposed project will develop an interactive computer-based program to provide cessation information and secondary prevention material to adolescent users of smokeless tobacco (ST). The Phase I prototype will combine CD-ROM and Internet technologies to deliver tailored content to both low-frequency and high-frequency ST users. The program will be developed ...

DESCRIPTION (provided by applicant): Functional MRI is capable of achieving millimeter spatial resolution in measurements of blood oxygenation associated with neural tissue activation in the brain, while the EEG is capable of achieving sub-millisecond temporal resolution of the electrical activity. Many studies can now benefit from the synergy of these two techniques, but simultaneous recording is ...

DESCRIPTION (provided by applicant): Electroencephalography is a safe, noninvasive technique for monitoring neonatal brain function. Acute and long-term EEG monitoring of infants has clinical utility for evaluating the effects of hypoxic ischemic insults and detecting the presence of epileptic activity. The information available in neonatal EEG can be greatly enhanced by using an adequate number o ...