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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A Synthetic Human Cytomegalovirus Vaccine Platform

    SBC: TOMEGAVAX, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The goal of this project is to synthesize, based on genomic sequence information, a human cytomegalovirus (HCMV) strain with demonstrated ability to establish persistent infection in sero-positive individuals. The resulting synthetic product will form the basis for the development of attenuated HCMV vaccines. Innovative synthetic biology methods will overcome ...

    STTR Phase I 2013 Department of Health and Human Services
  2. Position tracking and mobility assessment system for indoor monitoring of elders

    SBC: EMBEDRF LLC            Topic: NIA

    DESCRIPTION (provided by applicant): The goal of this project is to develop and evaluate a position tracking and mobility assessment system that will enable the elderly to live longer and more safely at home or in an assisted living facility. The ability to move is a critical function tat underlies the quality of life for the elderly. Changes in mobility such as speed of walking have been shown to ...

    STTR Phase II 2013 Department of Health and Human Services
  3. Instrumentation enabling a 16-fold decrease in oligonucleotide cost

    SBC: APDM, INC.            Topic: NIA

    DESCRIPTION (provided by applicant): Although balance and gait disorders are one of the most common and devastating chronic medical problems of older people, especially those with chronic neurological diseases, clinicians or clinical researchers do not measure balance and gait frequently, accurately, or sensitively. Our long-term goal is to develop and commercialize a unique system called the Hom ...

    SBIR Phase I 2013 Department of Health and Human Services
  4. A noninvasive optical imaging of retinal amyloid beta deposits in AD patients

    SBC: Oregon Center For Applied Science, Inc            Topic: NIDA

    DESCRIPTION (provided by applicant): Marital discord is a significant risk factor for a range of negative mental and physical health outcomes.1, 2 Individuals in unhappy relationships experience increases in stress, anxiety, functional impairment, and depressive symptoms3 and are at significant risk for substance abuse disorders.4-7 Furthermore, work loss associated with marital problems translate ...

    SBIR Phase I 2013 Department of Health and Human Services
  5. Integrin Targeted Therapy for the Treatment of Ovarian Cancer

    SBC: BIOSPEECH INC            Topic: NIDA

    Summary Sleep disordered breathing (SDB) is believed to be a widespread, under-diagnosed condition associated with detrimental health problems, at a high cost to society. The current gold standard for diagnosis of SDB is a time- consuming, expensive, and obtrusive (requiring many attached wires) sleep study, or polysomnography (PSG). The immediate objective of the proposed research is to develop a ...

    SBIR Phase I 2013 Department of Health and Human Services
  6. Human Monoclonal Antibody To Treat P. aeruginosa Infections in Cystic Fibrosis

    SBC: Advantage Silver Dental Arrest, LLC            Topic: NIDCR

    DESCRIPTION (provided by applicant): Topical fluorides have been the mainstay in the prevention of dental caries for decades. However, topical fluoride alone is not enough to thwart tooth decay in high-risk populations. The purpose of this Phase I application is to determine the technical and scientific feasibility of using a combination povidone-iodine (PVP-I)-5% sodium fluoride (NaF) varnish as ...

    SBIR Phase I 2013 Department of Health and Human Services
  7. High Cell Density Bioartificial Pancreas Enabled by Implantable Oxygen Generator

    SBC: Pacific Diabetes Technologies            Topic: NIDDK

    DESCRIPTION (provided by applicant): Type 1 diabetes often leads to short-term and long-term complications which impair quality of life. Though many research groups are developing versions of an artificial endocrine pancreas (AP) system, current systems require at least one hormone delivery insertion site and at least one glucose sensor site. This complexity limits commercial viability and potenti ...

    SBIR Phase I 2013 Department of Health and Human Services
  8. Promoting School Readiness and Successful Transitions through Parent Training

    SBC: MARKER GENE TECHNOLOGIES INC            Topic: NIGMS

    DESCRIPTION: This Small Business Innovation Research Phase I project aims to develop new targeted fluorogenic substrates capable of measuring enzyme activities in the Golgi apparatus and Endoplasmic Reticulum (ER) of living cells and tissues. If successful, the proposed research will provide breakthroughs needed to advance the discovery of promising new therapies and modulating drugs for neurodege ...

    SBIR Phase I 2013 Department of Health and Human Services
  9. Image-Based Quantification and Analysis of Longitudinal Lung Nodule Deformations

    SBC: TECH ASSISTANCE INST/INTELLECTUAL DISABL            Topic: NICHD

    DESCRIPTION (provided by applicant): The objective of this project is to create a web-based, interactive health communication application [IHCA]1 that promotes healthy physical and social development in young girls and adolescents with mild to moderate intellectual disability (MTM-ID). The program, Live Smart Live Safe(R): Healthy Development for Girls and Adolescents with Intellectual Disability ...

    SBIR Phase I 2013 Department of Health and Human Services
  10. Fathering through Change: Online Parent Training for Divorced Fathers

    SBC: IRIS MEDIA INC            Topic: NICHD

    DESCRIPTION (provided by applicant): Many fathers are unprepared for the stressors accompanying divorce that disrupt their effective parenting skills. Divorce rates remain high and fathers are gaining more custodial responsibilities than in the past, yet divorced fathers remain a vastly underserved population for which very few evidence-based programs even exist. There is great need for more spec ...

    SBIR Phase I 2013 Department of Health and Human Services

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