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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. EMG biofeedback with AMES

    SBC: AMES TECHNOLOGY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-range goal of this project is to restore functional movement to low-functioning stroke patients using a novel therapeutic regimen and robotic device called AMES, an acronym for Assisted Movement with Enhanced Sensation. In AMES-as it is currently used-the patient's affected limb is moved cyclically with the AMES robotic device while the sensation of ...

    SBIR Phase II 2009 Department of Health and Human Services
  2. Computer assisted disfluency counts for stuttered speech

    SBC: BIOSPEECH INC            Topic: N/A

    DESCRIPTION (provided by applicant): Stuttering is a communication disorder characterized by disfluencies that are frequent and disruptive to communication. Clinicians extensively use disfluency counts to decide whether a client should be treated, to assess treatment progress, and to document treatment outcomes. Clinicians often do disfluency counts in real-time as a speaker is talking. However, ...

    STTR Phase I 2009 Department of Health and Human Services
  3. Tools for Automated Assessment of Language

    SBC: BIOSPEECH INC            Topic: N/A

    DESCRIPTION (provided by applicant): Language and communication problems critically characterize a number of neurodevelopmental disorders including Developmental Language Disorders (DLD) and Autism Spectrum Disorders (ASD). It is increasingly recognized that assessment should include spontaneous natural language samples. There are measures, such as the Index of Productive Syntax (IPSyn), which are ...

    STTR Phase I 2009 Department of Health and Human Services
  4. Evaluating BMY-14802 as an anti-dyskinesia treatment in the 6-OHDA rat model of P

    SBC: SKYBRIDGE PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Our objective is to develop new drug treatments for the side effects of levodopa (L-DOPA) that occur in people with Parkinson's Disease. L-DOPA is the gold standard of treatment for Parkinson's, but unfortunately, the majority of people who take L-DOPA eventually develop debilitating side effects, abnormal involuntary movements called dyskinesias, which may aff ...

    SBIR Phase I 2009 Department of Health and Human Services
  5. Developing MRM-based proteomics software

    SBC: SINGLE ORGANISM SOFTWARE, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Multiple reaction monitoring (MRM) is a highly selective, high sensitivity mass spectrometry mode for detecting the presence of particular species in a mixture. In the pharmaceutical industry, many small molecule analytes (e.g. drug metabolites, hormones, and pesticides) are routinely measured in high throughput with MRM's great precision. MRM based assays are ...

    SBIR Phase I 2009 Department of Health and Human Services
  6. Web-based Alcohol Service Training for College Social Hosts

    SBC: DESCHUTES RESEARCH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Responsible beverage service (RBS) training originated some quarter century ago to prevent driving under the influence among patrons of public drinking establishments, from which half of DUI arrests and alcohol-related crashes originate. These programs train licensed servers of alcohol regarding medical and legal risks of providing and consuming alcohol. This p ...

    SBIR Phase II 2009 Department of Health and Human Services
  7. Interactive Multimedia Training Program for First Steps to Success Intervention

    SBC: DESCHUTES RESEARCH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): In the past decade, elementary school settings have been overwhelmed by increasing numbers of behaviorally at-risk children who are unresponsive to the minimal but necessary demands of schooling. It is of critical importance to get behaviorally at-risk children off this trajectory or pathway as soon as possible in their school careers through early, coordinated ...

    STTR Phase I 2009 Department of Health and Human Services
  8. Designed Antimalarial Agents Overcoming Chloroquine-Resistance

    SBC: DESIGNMEDIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): DesignMedix has developed a novel class of compounds to address the pressing need for an orally available, inexpensive drug to counter the spread of chloroquine-resistant malaria. Preliminary data showed that this novel class of molecules, called reversed chloroquines (RCQs), acts against both chloroquine- resistant and chloroquine-sensitive malaria in vitro. ...

    STTR Phase II 2009 Department of Health and Human Services
  9. Integrated EEG/NIR Sensor System for Infants

    SBC: Electrical Geodesics, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of the proposed project is to design a cost-effective, light-weight, integrated, whole- head EEG/NIR brain imaging and data analysis system for non-invasive recording of brain activity in neonates and young children. This system will permit bedside monitoring of immediate at-risk neonates, and early identification and intervention for ab ...

    SBIR Phase I 2009 Department of Health and Human Services
  10. Therapeutic thrombin analogs

    SBC: Aronora, Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Stroke and heart attack are the leading causes of mortality and grave morbidity. The goal of this Fast-Track STTR grant application is to enable preclinical investigation of WE-thrombin, a bioengineered protein C activator enzyme for the treatment of severe, acute thrombotic diseases, in particular ischemic stroke. WE- thrombin is a fundamentally new thrombosi ...

    SBIR Phase I 2009 Department of Health and Human Services

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