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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Pediatric Acceptable Formulation of Amiodarone

    SBC: ACADEMIC PHARMACEUTICALS            Topic: N/A

    DESCRIPTION (provided by applicant): IV amiodarone is the first line therapy for life threatening ventricular as well as supraventricular arrhythmias. However, the Tween 80 and benzyl alcohol diluents limits the rate of administration severely, due to hypotension and myocardial contractile depression. These adverse toxicities contribute to the high mortality of cardiac arrest patients who have ma ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  2. Controlled Release Vascular Grafts

    SBC: VesselTek Biomedical LLC            Topic: N/A

    DESCRIPTION (provided by applicant): In the United States, it is estimated that 8 million people suffer from peripheral artery disease (PAD). PAD is characterized by a gradual reduction in blood flow to the muscular arteries of the lower extremities caused by atherosclerosis. For those with severe PAD, lower extremity bypass grafting remains the predominant option for limb salvage. Although native ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  3. EMG biofeedback with AMES

    SBC: AMES TECHNOLOGY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-range goal of this project is to restore functional movement to low-functioning stroke patients using a novel therapeutic regimen and robotic device called AMES, an acronym for Assisted Movement with Enhanced Sensation. In AMES-as it is currently used-the patient's affected limb is moved cyclically with the AMES robotic device while the sensation of ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  4. Non-invasive Assessment of Insulin Resistance

    SBC: BIOCHEMANALYSIS CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The overall objective of this grant is to develop a non-invasive method for assessment of insulin resistance and impaired glucose tolerance (IGT) as a measure of pre-diabetes suitable for application to large-scale screening studies and to individualized preventive strategies in patients at risk for development of diabetes. This new approach is based on the kno ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  5. Computer assisted disfluency counts for stuttered speech

    SBC: BIOSPEECH INC            Topic: N/A

    DESCRIPTION (provided by applicant): Stuttering is a communication disorder characterized by disfluencies that are frequent and disruptive to communication. Clinicians extensively use disfluency counts to decide whether a client should be treated, to assess treatment progress, and to document treatment outcomes. Clinicians often do disfluency counts in real-time as a speaker is talking. However, ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  6. Tools for Automated Assessment of Language

    SBC: BIOSPEECH INC            Topic: N/A

    DESCRIPTION (provided by applicant): Language and communication problems critically characterize a number of neurodevelopmental disorders including Developmental Language Disorders (DLD) and Autism Spectrum Disorders (ASD). It is increasingly recognized that assessment should include spontaneous natural language samples. There are measures, such as the Index of Productive Syntax (IPSyn), which are ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  7. Development of novel tissue directed ultra sound therapeutic gene delivery system

    SBC: SONOGENE, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Low levels of high-density lipoprotein (HDL) cholesterol is an important risk factor for coronary heart disease (CHD). HDL cholesterol levels are predictive of major cardiovascular events in patients treated with statins. This relationship was also observed among patients with LDL cholesterol levels below 70 mg per deciliter. Studies have demonstrated that poly ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  8. Evaluating BMY-14802 as an anti-dyskinesia treatment in the 6-OHDA rat model of P

    SBC: SKYBRIDGE PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Our objective is to develop new drug treatments for the side effects of levodopa (L-DOPA) that occur in people with Parkinson's Disease. L-DOPA is the gold standard of treatment for Parkinson's, but unfortunately, the majority of people who take L-DOPA eventually develop debilitating side effects, abnormal involuntary movements called dyskinesias, which may aff ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  9. Developing MRM-based proteomics software

    SBC: SINGLE ORGANISM SOFTWARE, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Multiple reaction monitoring (MRM) is a highly selective, high sensitivity mass spectrometry mode for detecting the presence of particular species in a mixture. In the pharmaceutical industry, many small molecule analytes (e.g. drug metabolites, hormones, and pesticides) are routinely measured in high throughput with MRM's great precision. MRM based assays are ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  10. Instrument for assessment of pediatric binaural hearing abilities

    SBC: COMPREVAL, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The practice of evidence-based audiological (re)habilitation requires efficient, easy to use, standardized outcome assessment protocols and instruments with known reliability and validity. Such protocols and instruments are especially important for assessing the speech communication benefits of cochlear implants (CIs) in adults and children. The standard of car ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
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