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There is an increasing awareness about the problems associated with blood transfusions. One concernbacterial contamination of blood bags. If contaminated blood is transfused, the person receiving thebecoming sick and dying. Current standards require that blood be visually inspected before leaving tblood has an abnormal appearance, it is not used. This visual quality check is subject to human judgt ...

The objective of this research program is to demonstrate the feasibility of a new controlled-releasuse in an injectable formulation of buprenorphine to improve treatment of opioid dependence. The keytechnology is the use of bioerodible microporous microbeads with a controllable structure that allowas well as easily varied release rates and durations of release. These controlled-release microbeadsi ...

We will develop and test a model by which health plan report card information is disseminatedto publicly-sponsored consumers to use in selecting health care systems/plans. The model willincorporate a decision-making paradigm enabling Medicaid and Medicare beneficiaries to integratepersonal values/preferences, medical histories, etc. with features of health plans. Model developmentwill use both pri ...

Although taxol, paclitaxel, is one of the most promising anticancer drugs, the supply of taxol hasmarket demands. To date taxol production is limited and dependent on extraction from bark of yew treChemical synthesis of taxol gives low yield, semi- synthetic production requires a very large supplycell cultures in batch reactors provide low productivity. The overall goal of our project is to deveco ...

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This project addresses the need for sensitive and predictive measures that can identify elderlypersons at risk for falling, thereby preventing some of the human and societal costs of devastatinginjuries. Dynamic balance assessment methods will be combined with virtual-reality techniques toproduce an innovative technology for evaluating balance in simulated real-world environments. Presenttechnique ...

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A large and growing number of the residents of the United States speak English as a secondlanguage. Opportunities for employment, promotion, and education for this population can be negativelyaffected by their inability to communicate effectively in English. Little is known, however, about thespecific phonetic and phonological factors which affect the intelligibility of non-native speech. Thisproj ...

Every year approximately 16,000 to 20,000 school age children sustain traumatic brain injuries (TBIimpairment of cognitive abilities and physical functioning. The innate ability of TBI students to leenvironment is compromised because of their difficulty in receiving, processing, and storing new infhave memory impairments and process information at reduced rates. If the TBI student is presented wim ...