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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A FAP-Activated Proteasome Inhibitor for Killing Solid Tumors

    SBC: ARISAPH PHARMACEUTICALS, INC.            Topic: 102

    DESCRIPTION provided by applicant Cancer is the second leading cause of death after heart disease in the US Chemotherapy is a mainstay of treatment after surgical removal of tumors but the balance of clinical benefit versus disabling or life threatening side effects is often uncertain Genotyping of cancers to identify mutated oncogenes has enabled an era of targeted therapy Drugs targeting ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. A NEW METHOD FOR THE ANALYSIS OF VITAMIN D

    SBC: NOVILYTIC, LLC            Topic: 100

    DESCRIPTION provided by applicant Most clinical assays begin with blood collection in a laboratory setting The Gates foundation and many others have recognized and attempted to deal with the fact that in much of the world clinical testing is done in a primitive setting The luxury of having a phlebotomist to draw blood with a laboratory to prepare serum or plasma for analysis is not universal ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. A Practical Tool for Managing the Complexity of Biologics Process Manufacturing

    SBC: ADVANCED PROCESS COMBINATORICS, INC.            Topic: 100

    DESCRIPTION provided by applicant Biologics manufacturing based on cell culture techniques represents a tremendous advance in the pharmaceutical industry The use of biological rather than chemical processes result in unique therapeutics with greater profitability a knowledge based barrier to entry and the ability to develop therapeutics targeted at specific subsets of the population i e p ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. A rapid response detector system for intensity modulated proton therapy dosimetry

    SBC: PHENIX MEDICAL LLC            Topic: NCI

    DESCRIPTION provided by applicant In recent years there has been increased interest throughout the world in the use of proton radiation therapy for treatment of cancer and independent studies project a annual increase in the installed base The replacement of X ray therapy with proton therapy will have substantial long term benefit to patients due to greatly reduced long and short term tox ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. A Software Platform for Sensor based Movement Disorder Recognition

    SBC: ALTEC Inc            Topic: 102

    DESCRIPTION provided by applicant The goal of this Phase II is to enhance the availability of advanced brain and behavior research tools PA by developing an automated sensor based means of tracking the presence and severity of a broad spectrum of movement disorders during unscripted activities of daily living The continuously updated and interpreted information from body worn sensors ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  6. A uMECS miniature blower for respiratory protection systems, Phase II

    SBC: Vibrant Composites Inc.            Topic: CBD14103

    Air management solutions capable of reducing heat and moisture burden are not suitable for integration in wearable respiratory protection systems due to excessive weight, volume, and power requirements of existing technologies. Vibrant Composites proposes applying its unique uMECS manufacturing technology towards development of an ultra-lightweight and power efficient miniature blower. Fundamental ...

    SBIR Phase II 2015 Department of DefenseOffice for Chemical and Biological Defense
  7. A Wireless Sensor System for Reliable Recordings During Exercise

    SBC: ALTEC Inc            Topic: NICHD

    DESCRIPTION provided by applicant Despite recent advancements in wireless sensor technology and the rapidly growing need among clinicians and researchers for body worn measurement systems current technology retains limited functionality during demanding applications such as recording uncontrolled movement disorders sports activities or activities in the work place A design breakthrough is ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Advanced LWIR Hyperspectral System for On-the-Move Standoff Detection of Liquid and Solid Contaminants on Surfaces

    SBC: Physical Sciences Inc.            Topic: CBD12104

    Physical Sciences Inc. (PSI) proposes to utilize an innovative LWIR hyperspectral technology coupled with advanced data processing algorithms for non-contact, standoff detection of liquid/solid contaminants on surfaces. The technology will address the US Army"s need for fast, on-the-move, non-contact detection of ground contamination during reconnaissance missions. The Phase I effort demonstrated ...

    SBIR Phase II 2014 Department of DefenseOffice for Chemical and Biological Defense
  9. Amelioration of Claustrophobia and Disruptive Patient Motion in MR Imaging

    SBC: HYPNALGESICS, LLC            Topic: 213

    DESCRIPTION provided by applicant Claustrophobia and disruptive patient motion longtime common impediments to MRI examination can be prevented or ameliorated with a non pharmacologic behavioral intervention administered by trained staff The potential benefits of such an intervention are highly significant as current practice alternatives are to cancel the study or administer sedation Inabilit ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. An Integrated THz System for DNP-enhanced NMR Spectroscopy

    SBC: BRIDGE 12 TECHNOLOGIES, INC.            Topic: 100

    DESCRIPTION provided by applicant The proposed research focuses on the development of a DNP NMR system for Dynamic Nuclear Polarization DNP enhanced solid state NMR spectroscopy at MHz High resolution structures are essential to the understanding of the complex functions of bio macromolecules and NMR spectroscopy is a major source for such information However the method suffers from an ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health

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