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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Accelerated Discovery and Development of New Pain Therapeutics

    SBC: AESTUS THERAPEUTICS, INC.            Topic: NINDS

    DESCRIPTION (provided by applicant): Neuropathic pain is a common complication of cancer, diabetes mellitus, viral infections, and other causes. Although physicians currently employ a variety of treatments to manage moderate to severe neuropathic pain, including non-steroidal anti-inflammatory drugs, opioids, tricyclic antidepressants, anti- seizure medications, serotonin-norepinephrine reupta ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  2. A Clinically Practical Laser System for Neurosurgery

    SBC: LIGHT AGE, INC.            Topic: NCRR

    DESCRIPTION (provided by applicant): Results of recent Free Electron Laser (FEL) studies have shown that under certain conditions pulsed 6-7 5m radiation can affect scission of soft tissues with unprecedented precision and minimal damage to tissues immediately adjacent to the scission sites. Subsequent clinical work has successfully employed this FEL output in several pilot human neurosurgeries. U ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  3. A Computerized Adaptive Testing Version of the ASI

    SBC: Inflexxion, Inc.            Topic: NIDA

    DESCRIPTION (provided by applicant): This Phase II application proposes to continue development of the ASI-MV-CAT, a Computer Adaptive Testing edition of Inflexxion's popular Addiction Severity Index-Multimedia Version (ASI-MV). Built on the ASI, probably the most widely used adult assessment for substance use problems in the US, the ASI-MV provides a reliable, valid and cost-effective version for ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  4. A Culture-Free Platform for Rapid Pathogen Identification

    SBC: HELIXBIND, INC.            Topic: R

    DESCRIPTION provided by applicant Fungal sepsis or fungemia is a serious public health concern afflicting over patients every year in the US where almost of those do not survive In fungemia early targeted treatment is life saving and considering the rate at which the disease develops is perhaps the most crucial factor to improving outcomes Unfortunately given the time consumi ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Advanced Electrostatic Computation in Molecular Dynamics

    SBC: CONTINUUM DYNAMICS INC            Topic: NIGMS

    DESCRIPTION (provided by applicant): Advances in computational hardware and molecular modeling techniques have revolutionized our ability to simulate electrostatic interactions, which play a fundamental role in the conformational stability, structure, folding and function of biomolecules. One important near-term application of these developments drawing both theoretical and commercial interests is ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  6. Advanced LWIR Hyperspectral System for On-the-Move Standoff Detection of Liquid and Solid Contaminants on Surfaces

    SBC: PHYSICAL SCIENCES INC.            Topic: CBD12104

    Physical Sciences Inc. (PSI) proposes to utilize an innovative LWIR hyperspectral technology coupled with advanced data processing algorithms for non-contact, standoff detection of liquid/solid contaminants on surfaces. The technology will address the US Army"s need for fast, on-the-move, non-contact detection of ground contamination during reconnaissance missions. The Phase I effort demonstrated ...

    SBIR Phase II 2014 Department of DefenseOffice for Chemical and Biological Defense
  7. Advancing a Mucosal HSV-2 Vaccine Towards Clinical Trials

    SBC: Biomedical Research Models, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Globally, an estimated 16.2% of the human population is infected with HSV-2 including gt17% of the U.S. adult population. Genital herpes is associated with an increased risk of HIV acquisition and transmission and HSV-2infection can cause neonatal herpes with high infant mortality. HSV-2 infection in the adult population has increased substantially in the past ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Advancing a Mucosal HSV-2 Vaccine Towards Clinical Trials

    SBC: Biomedical Research Models, Inc.            Topic: R

    DESCRIPTION provided by applicant Globally an estimated of the human population is infected with HSV including andgt of the U S adult population Genital herpes is associated with an increased risk of HIV acquisition and transmission and HSV infection can cause neonatal herpes with high infant mortality HSV infection in the adult population has increased substantially in the ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. A FAP-Activated Proteasome Inhibitor for Killing Solid Tumors

    SBC: ARISAPH PHARMACEUTICALS, INC.            Topic: 102

    DESCRIPTION provided by applicant Cancer is the second leading cause of death after heart disease in the US Chemotherapy is a mainstay of treatment after surgical removal of tumors but the balance of clinical benefit versus disabling or life threatening side effects is often uncertain Genotyping of cancers to identify mutated oncogenes has enabled an era of targeted therapy Drugs targeting ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Affordable Cryogen-Free Point-of-Care 1.5 T Extremity MRI

    SBC: Superconducting Systems, Inc.            Topic: NIAMS

    DESCRIPTION provided by applicant The overall goal of this Fast Track project is to combine innovations in superconducting magnet design and new developments in solid state MRI to create a highly compact robust mobile lightweight and affordable MRI for scanning the peripheral skeleton including the knee of the majority of the public This scanner will use a unique cryogen free bore act ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
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