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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. ZircLight: Spectrum-specific lighting for shift work

    SBC: CIRCADIAN MANAGEMENT, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant Epidemiologic evidence has established that shift work exposure is associated with an array of adverse health consequences including increased risk of cardiovascular disease gastrointestinal disease and cancer Investigations of the mechanisms linking shift work and disease have highlighted the importance of nocturnal light exposure and the consequent ch ...

    SBIR Phase II 2014 Department of Health and Human Services
  2. Whole Eye Biometry System

    SBC: Physical Sciences Inc.            Topic: N

    DESCRIPTION provided by applicant Physical Sciences Inc PSI proposes to demonstrate a new dual conjugate dual band approach to whole eye optical biometry We will adapt a high speed SDOCT based scanning imaging system design recently developed for corneal scleral topography for application to the whole eye That system was based upon an ellipsoidal optical scanning imaging design that pro ...

    SBIR Phase II 2015 Department of Health and Human Services
  3. Web-based Support to Manage Arthritis Pain

    SBC: Inflexxion, Inc.            Topic: NIAMS

    DESCRIPTION (provided by applicant): One of every five adults in the United States (46.4 million people) is affected by arthritis. Increasing the number of days individuals are free of arthritis pain is one of the Healthy People 2010 objectives. Although there are a variety of medical treatments and medications available, self-management is a critical component in helping arthritis sufferers learn ...

    SBIR Phase II 2010 Department of Health and Human Services
  4. Water-Window Soft X-Ray Microscope for Small Laboratories

    SBC: ENERGETIQ TECHNOLOGY, INC.            Topic: NCRR

    DESCRIPTION (provided by applicant): Soft x-ray microscopy shows enormous promise as a technique for imaging cellular structures at resolutions well beyond what can be achieved in optical microscopes, and with much simpler sample preparation than is required for electron microscopy. In addition, the lower radiation dose required (compared to electron microscopy) allows tomographic investigation of ...

    SBIR Phase II 2010 Department of Health and Human Services
  5. vascuCAP: Non-invasive Computer-Aided Phenotyping of Vasculopathy

    SBC: Elucid Bioimaging Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant Vasculopathy encompasses a group of vascular diseases which includes atherosclerosis a major disease with enormous societal impact Atherosclerosis is implicated in many cardiovascular diseases including myocardial infarction peripheral vascular disease and stroke Approaches have been proposed for improving diagnostics where inconclusive or misleading inf ...

    SBIR Phase II 2015 Department of Health and Human Services
  6. User-centered control of hearing aid signal processing

    SBC: BOSE CORPORATION            Topic: N

    DESCRIPTION provided by applicant Finding the signal processing parameter values that are most appropriate for an individual patient is one of the essential components of hearing aid fitting In common practice the hearing aid user only plays a small role in selecting these values This proposal describes a data driven method for empowering users to select their desired parameter values by adj ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Upper Extremity Frailty Assessment Tool

    SBC: BioSensics LLC            Topic: N

    DESCRIPTION provided by applicant BioSensics LLC in collaboration with the Department of Surgery at the University of Arizona proposes to develop clinically validate and commercialize the Upper Limb Frailty Meter UFM a novel wearable technology for quantifying frailty in older trauma patients It is necessary to quantify frailty in these patients to ensure tat treatment is appropriate r ...

    SBIR Phase II 2015 Department of Health and Human Services
  8. Ultra-High Precision Laser Isotope Monitor for I3CO2, CO180 and CO170

    SBC: Aerodyne Research, Inc.            Topic: 831RC

    Greenhouse gas (GHG) emissions are primary drivers of global climate change. Hence there is a crucial need to quantify their sources and sinks. A powerful method to constrain source and sink strengths is the analysis of the relative proportions of isotopic variants of GHG’s in atmospheric samples like those collected globally by NOAA’s Cooperative Air Sampling Network. Measurements that are ca ...

    SBIR Phase II 2015 Department of CommerceNational Oceanic and Atmospheric Administration
  9. Treatment of congenital heart disease associated pulmonary hypertension

    SBC: RADIKAL THERAPEUTICS, INC.            Topic: NICHD

    DESCRIPTION provided by applicant Restoration of the balance of the free radicals nitric oxide NO and superoxide in the pulmonary vasculature may prevent life threatening perioperative pulmonary hypertension PH in children with congenital heart defects CHD undergoing surgical correction of a left to right shunt In rodent models of PH intratracheal IT administration of R a bifunct ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Transforming Dialysis into a Controlled Drug Delivery System for Stem Cell Derive

    SBC: Sentien Biotechnologies, Inc.            Topic: NIDDK

    DESCRIPTION (provided by applicant): The goal of this Phase IIB SBIR application is to test the Sentien cellular bioreactor product (the Sentinel ) in a first-in-man study to assess safety and preliminary efficacy. Fifteen post-cardiac surgery patients that are diagnosed with acute kidney injury and indicated for dialysis will be enrolled and connected to the Sentinel containing one of three escal ...

    SBIR Phase II 2014 Department of Health and Human Services

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