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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. User-centered control of hearing aid signal processing

    SBC: BOSE CORPORATION            Topic: N

    DESCRIPTION provided by applicant Finding the signal processing parameter values that are most appropriate for an individual patient is one of the essential components of hearing aid fitting In common practice the hearing aid user only plays a small role in selecting these values This proposal describes a data driven method for empowering users to select their desired parameter values by adj ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Ultra-High Precision Laser Isotope Monitor for I3CO2, CO180 and CO170

    SBC: Aerodyne Research, Inc.            Topic: 831RC

    Greenhouse gas (GHG) emissions are primary drivers of global climate change. Hence there is a crucial need to quantify their sources and sinks. A powerful method to constrain source and sink strengths is the analysis of the relative proportions of isotopic variants of GHG’s in atmospheric samples like those collected globally by NOAA’s Cooperative Air Sampling Network. Measurements that are ca ...

    SBIR Phase II 2015 Department of CommerceNational Oceanic and Atmospheric Administration
  3. Treatment of congenital heart disease associated pulmonary hypertension

    SBC: RADIKAL THERAPEUTICS, INC.            Topic: NICHD

    DESCRIPTION provided by applicant Restoration of the balance of the free radicals nitric oxide NO and superoxide in the pulmonary vasculature may prevent life threatening perioperative pulmonary hypertension PH in children with congenital heart defects CHD undergoing surgical correction of a left to right shunt In rodent models of PH intratracheal IT administration of R a bifunct ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Surveying Earth's Gravity with Unmanned Aerial Vehicles

    SBC: AURORA FLIGHT SCIENCES CORPORATION            Topic: 91

    During the Phase I program, Aurora conducted a comprehensive survey of potential platforms that included government owned and furnished UAVs and manned aircraft as well as Aurora’s Centaur Optionally Piloted Aircraft (OPA). The survey concluded, in part, that UAVs offer a significant improvement in data collection capability when compared to manned aircraft that are currently fielded by NOAA. ...

    SBIR Phase II 2014 Department of CommerceNational Oceanic and Atmospheric Administration
  5. Rapid and On-site Monitoring of Urinary Arsenic Metabolites

    SBC: Giner, Inc.            Topic: NIEHS

    DESCRIPTION provided by applicant Giner Inc proposes a portable inexpensive and rapid response monitor for arsenic speciation in urine Arsenic species excreted in urine are reflective of exposure to toxic arsenic species and therefore this monitor will be a valuable tool in medical diagnostics and epidemiological studies by allowing determination of arsenic exposure by a technique that is ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Prevention of HIV/AIDS and STDs in Women over Fifty

    SBC: Environment And Health Group, Inc.            Topic: NIA

    DESCRIPTION provided by applicant Older adult women age account for almost a third of the U S HIV AIDS population and infection rates among this group are increasing The overall goal of the proposed Phase II application is to develop a culturally sensitive gender specific and age appropriate HIV prevention intervention for older women especially African American and Latino women wh ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Portable Gas Perfusion System for Pancreas Preservation

    SBC: Giner, Inc.            Topic: 200

    DESCRIPTION provided by applicant Pancreatic islet transplantation ITx is an emerging treatment for a subset of Type diabetics for which standard insulin therapies are insufficient I is a promising alternative to pancreas transplantation since ITx has significantly less surgical risk and a less toxic immunosuppression regimen Enhanced organ preservation via the proposed technology has th ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Optimization of novel pyranopyridine efflux pump inhibitors

    SBC: MICROBIOTIX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Multi drug resistance MDR in Gram negative pathogens including the Enterobacteriaceae and Pseudomonas aeruginosa poses a significant threat to our ability to effectively treat infections caused by these organisms A major component in the development of the MDR phenotype in Gram negative bacteria is overexpression of RND type efflux pumps which actively pu ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Optical Surgical Probe for Assessing Human Oral Mucosa Graft Vascularization

    SBC: Radiation Monitoring Devices, Inc.            Topic: NIDCR

    DESCRIPTION provided by applicant Devastating and disfiguring facial injuries can result from gunshot wounds and motor vehicle accidents as well as from cancer surgeries of the head and neck or breast The most advanced reconstructive procedures involve distant transfer of tissue including bone periosteum skin muscle and vasculature followed microsurgical anastomosis of pre existing blood ve ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Novel commensal polysaccharide treats multiple sclerosis through Treg modulation

    SBC: SYMBIOTIX BIOTHERAPIES, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Multiple sclerosis MS is a chronic demyelinating inflammatory disease that is the most common neurological disease of young adults affecting over patients in the US and over million patients worldwide MS is a disease of high unmet medical need currently treatable with one of twelve FDA approved drugs all of which result in either significant i ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health

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