Award Data

ABSTRACTThe global death toll from Malaria is estimated to be upwards ofpeople each yearwith more thanchildren succumbing every dayPlasmodium falciparumPfSporozoiteSPZbased vaccines are the only intervention in humansproven to induce robusthigh levelandgtand long lastingat leastmonthsprotective efficacy against malariaforming the basis of Sanaria s unique technology platform of asepticpurifiedcryo ...

Abstract for Supplement ApplicationThe ultimate goal for our original project was to complete the proof-of-concept work, and the multitude of pharmacodynamic, pharmacokinetic, toxicokinetic, safety, and toxicology studies required by the FDA to apply for an IND. We are fully satisfied that we have generated a new chemical entity that acts at a novel binding site on the GABA-A receptor and acts in ...

The myCare2 solution will be marketed to cancer care organizations and include three separate portals for cancer caregivers, patients and providers. The system will be mobile-enabled and support standards-based EHR integration. Primary myCare2 features include symptom assessment, communication with the care team, care plan dissemination, tailored education content for caregiving and for caregiver ...

TECHNICAL ABSTRACT: Buoyancy driven oceanographic gliders, although reasonably cost effective, have challenges operating in the zones due to high gradients in water density. Under this topic, Riptide will provide a cost-effective autonomous undersea vehicle (AUV) design leveraged from Riptide's family of man-portable AUVs that can more effectively map the hypoxic areas. The stated goals of this to ...

TECHNICAL ABSTRACT: Triton Systems, Inc. proposes development of the Open-Source Oceanographic Asset Recovery Beacon (OpenORB) that will allow the deployment of coastal instrumentation moorings with affordable protection against loss. This open-source kit would significantly reduce the purchase price of a commercial location beacon by allowing the end-user to assemble a customized system with mini ...

TECHNICAL ABSTRACT: Poor air quality represents a major public health risk, contributing to an estimated one of every eight deaths worldwide. Low-cost air quality sensors have developed rapidly over the last few years and offer the opportunity to make air quality monitoring inexpensive and widespread. However, low-cost sensors are currently unable to deliver accurate, reliable data due to a lack o ...

TECHNICAL ABSTRACT: Recent advances in gas chromatographic (GC) and mass spectrometric (MS) techniques for atmospheric measurements have led to highly complex data sets that have overwhelmed the capabilities of current data analysis software. We propose a new method for the automated reduction of chromatographic data using peak-fitting algorithms. By relying upon constrained peak-fit parameterizat ...

TECHNICAL ABSTRACT: We propose to continue the development of a generalized 3DVAR data assimilation module, in an open-source and non-proprietary programming language, which is compatible with FVCOM and incorporated into the Lake Erie Operational Forecast System (LEOFS). We will leverage our experience and expertise in using 3DVAR for a ROMS-based real-time forecast system for the California coast ...

TECHNICAL ABSTRACT: The Hybrid Quadrotor concept, developed by Latitude Engineering, combines the high power density of electric motors and propellers with the high energy density of a piston engine and liquid fuel. Together, each technology enables maximum performance in HQ's two regimes of flight: the electric system is responsible for lift while hovering (high power, short endurance), and the g ...

TECHNICAL ABSTRACT: Tropospheric oxidation capacity is dominated by HOx photochemistry, however halogen atoms and oxides significantly affect these chemical cycles. A sensitive and robust measurement of gaseous HCl is critically important to improve our understanding of halogen chemistry and its impacts on the spatial and temporal oxidation capacity of the atmosphere. In Phase I, we met all of our ...