Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. T7 RNA polymerase engineering and RNA amplification

    SBC: Accacia International LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Expanding use of microarray systems for global gene expression profiling is leading biological research, providing diagnostic and prognostic value to physicians and facilitating target discovery during drug and vaccine development. There is strong interest in extending this microarray capability to more RNA-limited material to the point that a single cell can b ...

    STTR Phase II 2007 Department of Health and Human Services
  2. High resolution mapping of the cochlear nerve using optical stimulation

    SBC: Aculight Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Neural prosthetic devices are artificial extensions to the body that restore or supplement nervous system function that was lost during disease or injury. Particular success has been realized in the cochlear prostheses development. In contemporary cochlear implants, however, the injected electric current is spread widely along the scala tympani and across turns ...

    STTR Phase II 2007 Department of Health and Human Services
  3. Study of CdZnTe Electrode Interface and Fabrication Technology Development

    SBC: Aguila Technologies, Inc.            Topic: N/A

    Not avaiable.

    STTR Phase II 2007 Department of Health and Human Services
  4. Stem Cells for Neonatal Hypoxic-Ischemic Brain Injury

    SBC: ATHERSYS, INC.            Topic: N/A

    DESCRIPTION: The specific objective of this STTR Phase II research and development project is to provide an optimized cellular therapy regimen for treating hypoxic-ischemic (HI) injury and its related outcomes in neonates. Pre- clinical studies performed in a rat pup model of HI injury as part of the funded Phase I STTR grant, point to benefit when Multipotent Adult Progenitor Cells (MAPC), a plur ...

    STTR Phase II 2007 Department of Health and Human Services
  5. Development of Improved Earphone for Hearing Testing

    SBC: AUDIOLOGY, INC            Topic: N/A

    DESCRIPTION (provided by applicant): This project seeks to develop an earphone for diagnostic audiometry with features that will significantly increase the efficiency and decrease the cost of routine hearing testing. The most-often used earphones employ a supra-aural design that has several undesirable characteristics, including 1) an "occlusion effect", an artificial increase in sensitivity to bo ...

    STTR Phase II 2007 Department of Health and Human Services
  6. Fast Biosequence Annotation via Reconfigurable Hardware

    SBC: BECS Technology, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Databases of biological sequences have proven valuable for understanding the organization of human and other genomes, for unraveling the etiology of genetic disorders, and for studying medically important pathogens. Unfortunately, these databases are growing at an exponential rate, posing a severe problem for bio-sequence annotation. Specialized hardware implem ...

    STTR Phase II 2007 Department of Health and Human Services
  7. Bioscience Research Integration Software Platform

    SBC: BIOFORTIS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The need to investigate and understand all elements of biological information pertinent to disease is more clearly evident now than ever before. However, the avalanche of non-integrated data produced by today's technologies prevents scientists from effectively reducing these data to meaningful discoveries. As a result, the vast bulk of data collected through ...

    STTR Phase II 2007 Department of Health and Human Services
  8. Phenotype MicroArray Analysis of Fastidious Pathogens

    SBC: BIOLOG, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Mycobacterium tuberculosis and other Mycobacterium species are major pathogens around the world. They are part of a larger group of so-called fastidious pathogens that are difficult to study because, for a wide range of reasons, they are difficult to culture. Phenotype MicroArrayTM (PM) technology is a tool that can aid in understanding the physiological and me ...

    STTR Phase II 2007 Department of Health and Human Services
  9. Expired CO2/O2 Analysis to Diagnose Pulmonary Embolism

    SBC: BREATHQUANT MEDICAL SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): A rapid, noninvasive, and accurate, point-of-care device to diagnose and exclude pulmonary embolism (PE) remains an unmet need, especially for patients with conditions that activate inflammatory and coagulation pathways and therefore predispose to PE. These conditions include surgery, cancer, age >70 years, prolonged hospitalization, hemodialysis, connective ti ...

    STTR Phase II 2007 Department of Health and Human Services
  10. Targeted antimicrobial therapy for dental caries

    SBC: C3 JIAN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Extensive research in the past 50 years has demonstrated that Dental caries is a microbial infection caused by a limited number of cariogenic bacteria (i.e., Streptococcus mutans) that co-reside with over 400 other non-harmful/commensal microbial species in the Dental plaque. The current anti-microbial strategies used to treat Dental caries have consisted prima ...

    STTR Phase II 2007 Department of Health and Human Services
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