Award Data

Our proposal is constructed around a mature, government-owned, distributed simulation architecture known as Joint Force Operational Readiness Combat Effectiveness Simulator (JFORCES) and a proven three-step computer-aided methodology known as Rapid Relational Modeling (RRM). The proposal includes definition, structuring and prioritizing of project goals and requirements using consensus of end-use ...

Aerotonomy, Incorporated (AI) and subcontractor Georgia Tech Research Institute (GTRI) will apply the latest knowledge in circulation control and piezo-electric synthetic (zero net mass flux) jet actuators (SJAs) to develop a practical small UAV with no hinged control surfaces. In the area of flow control, low jet momentum coefficient SJAs have been used primarily as a mechanism to keep flow atta ...

DESCRIPTION (provided by applicant): Founded in 1998, Altea Therapeutics is developing its PassPort(tm) transdermal drug delivery system to deliver proteins and peptides, small-molecule drugs, genes and vaccines from a skin patch, eliminating the need for invasive needle injection. This breakthrough technology, currently undergoing Phase 1 clinical trials for transdermal delivery of insulin and ...

DESCRIPTION (provided by applicant): Apeliotus Technologies proposes to develop a commercial diagnostic for the early detection of age-related macular degeneration (ARMD). It relies on a functional test of dark adaptation kinetics (the transition from being light-adapted to being dark-adapted) that has been shown in previous work to detect the onset of ARMD at least four years before it is clinic ...

DESCRIPTION (provided by applicant): Approximately 10 million people in the U.S. are estimated to have osteoporosis, a disease that results in over 1.5 million bone fractures a year. It is now known that the accumulation of fat cells (adipocytes) in bone marrow is a major factor contributing to age-related bone loss. Women with osteoporosis have higher numbers of marrow adipocytes than those wome ...

DESCRIPTION (provided by applicant): A novel microarray-based system is proposed for diagnosis of tuberculosis and tuberculosis-like respiratory infections. This diagnostic system offers a parallel method to screen clinical samples for the presence of DNA sequences from Mycobacterium tuberculosis, the causative agent of human tuberculosis, and closely related mycobacterial species, while simultan ...

The goal of this effort is to grow n and p ZnO thin films by MOCVD on ZnO substrates. The primary objective of this phase I effort will be to grow p-n homojucntion and characterize the LED structure. Bandgap of ZnO will be engineered and heterojunction quantum wells will be grown. The grown device structures will be characterized for structure and quality by X-ray, PL and electron microscopy, The ...

Dynamic Sensors, Incorporated (DSI) proposes a superior approach to Algorithms for Hyper-spectral Image Processing for the problem of spatial-spectral-temporal measurements of transient phenomena. DSI will demonstrate a Machine Intelligent Processor (MIP) software tool for rapid identification of dynamic battlefield events. MIP is an image analysis approach that is based on a neurobiological mod ...

DESCRIPTION (provided by applicant): Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in the U.S. and is associated with an imbalance in proteolytic activity in the lungs. Treatment is largely aimed at symptom remediation using bronchodilators and corticosteroids, but these do not treat the underlying disease process. We are developing a gene-based therapy to treat ...

Currently aircraft composite and metal structures are joined by fastening them in place using riveted or bolted joints. Although fastened joints largely avoid concerns associated with thermally induced stresses and strains from CTE mismatches, such designs add weight, manufacturing complexity and cost to the design. Recent advances have given rise to new opportunities to increase the integrity a ...