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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. FAS/FAE Multimedia Tools for Care Providers

    SBC: ACADEMIC EDGE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Prenatal exposure to alcohol is the leading causing of birth defects in the United States. Recent studies show prevalence rates in the US may be as high as 1% of live births (Burd L, Cotsonas-Hassler, et al., 2003). This means that each year, as many as 39,000 babies are born with FAS. Many more are born with fetal alcohol effects (FAE). Early diagnosis and app ...

    SBIR Phase II 2005 Department of Health and Human Services
  2. Teratogen Warnings and Educational Media

    SBC: ACADEMIC EDGE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The prescription of pharmaceuticals with teratogenic properties has increased rapidly over the past decade, with the heightened use of Accutane, thalidomide and other birth-defect inducing drugs. The CDC found the warni ng symbol in use at the time of the study on some teratogenic pharmaceuticals to be confusing and subject to harmful misinterpretation. The war ...

    SBIR Phase II 2005 Department of Health and Human Services
  3. Transdermal Hydromorphone for Acute and Chronic Pain

    SBC: Altea Therapeutics Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Founded in 1998, Altea Therapeutics is developing its PassPort(tm) system to deliver proteins and peptides, small-molecule drugs, genes and vaccines from a skin patch, eliminating the need for invasive needle injection. This breakthrough technology, currently undergoing Phase 1 clinical trials for basal insulin delivery, revolutionizes the way in which medicine ...

    SBIR Phase II 2005 Department of Health and Human Services
  4. Non-Invasive Drug Delivery by Thermal Microporation

    SBC: Altea Therapeutics Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Founded in 1998, Altea Therapeutics is developing its PassPort(tm) transdermal drug delivery system to deliver proteins and peptides, small-molecule drugs, genes and vaccines from a skin patch, eliminating the need for invasive needle injection. This breakthrough technology, currently undergoing Phase 1 clinical trials for transdermal delivery of insulin and ...

    SBIR Phase I 2005 Department of Health and Human Services
  5. Diagnostic for Age-Related Macular Degeneration

    SBC: APELIOTUS TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Apeliotus Technologies proposes to develop a commercial diagnostic for the early detection of age-related macular degeneration (ARMD). It relies on a functional test of dark adaptation kinetics (the transition from being light-adapted to being dark-adapted) that has been shown in previous work to detect the onset of ARMD at least four years before it is clinic ...

    SBIR Phase I 2005 Department of Health and Human Services
  6. Flavonoid Compounds for the Prevention of Osteoporosis

    SBC: Aptotec, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Approximately 10 million people in the U.S. are estimated to have osteoporosis, a disease that results in over 1.5 million bone fractures a year. It is now known that the accumulation of fat cells (adipocytes) in bone marrow is a major factor contributing to age-related bone loss. Women with osteoporosis have higher numbers of marrow adipocytes than those wome ...

    SBIR Phase I 2005 Department of Health and Human Services
  7. MethLock vs. heparin as dialysis catheter lock

    SBC: ASH ACCESS TECHNOLOGY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Currently about 25% of patients on hemodialysis therapy for End Stage Renal Disease (ESRD) receives dialysis through tunneled central venous catheters for dialysis (CVCD). The standard anticoagulant lock for these catheters is heparin, which has no antibacterial properties. The greatest risk for ESRD patients using CVCDs access is catheter related bloodstream i ...

    SBIR Phase I 2005 Department of Health and Human Services
  8. Avian transgenesis via site-directed integration

    SBC: AviGenics Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase II SBIR project describes a novel method to create transgenic poultry that will produce biopharmaceutical proteins in their eggs. Chickens are able to produce large amounts of protein in their eggs at relatively low cost. We seek to harness this capability to synthesize pharmaceutical proteins, such as humanized monoclonal antibodies, that are neede ...

    SBIR Phase II 2005 Department of Health and Human Services
  9. Speech Perception Assessment and Training System

    SBC: COMMUNICATION DISORDERS TECHNOLOGY, INC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal is a software Speech Perception Assessment and Training System (SPATS) for the aural rehabilitation of adult hearing aid and cochlear-implant users. The system will assess the user's ability to identify the constituents of English syllables; that is, syllable onsets, nuclei, and codas in quiet and in background noise, and it will provide individualized ...

    SBIR Phase II 2005 Department of Health and Human Services
  10. Cord Blood Stem Cell Expansion Ex Vivo With Endothelial Progenitor Cells

    SBC: Endgenitor Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Bone marrow transplantation is an effective means to treat patients with inherited or acquired defects in blood formation. However, only 1/3 of the potential recipients can find suitable donor grafts. Human umbilical cord blood contains sufficient hematopoietic stem (HSC) and progenitor cells to engraft related recipients (even adults). A limitation to more wid ...

    SBIR Phase I 2005 Department of Health and Human Services

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