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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A Device for Measuring Gas Polarization

    SBC: Advanced Liquid Crystal Technologies            Topic: N/A

    DESCRIPTION (provided by applicant): This project is to develop an instrument to measure the polarization of a hyperpolarized noble gas, Helium- 3 and Xenon-129, for enhanced lung MRIs in a clinical environment. It is essential to have some means of measuring polarization at various stages in the handling of these gases, e.g. at production, storage, transport and administration to a patient. Th ...

    SBIR Phase II 2005 Department of Health and Human Services
  2. Transdermal Hydromorphone for Acute and Chronic Pain

    SBC: Altea Therapeutics Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Founded in 1998, Altea Therapeutics is developing its PassPort(tm) system to deliver proteins and peptides, small-molecule drugs, genes and vaccines from a skin patch, eliminating the need for invasive needle injection. This breakthrough technology, currently undergoing Phase 1 clinical trials for basal insulin delivery, revolutionizes the way in which medicine ...

    SBIR Phase II 2005 Department of Health and Human Services
  3. Non-Invasive Drug Delivery by Thermal Microporation

    SBC: Altea Therapeutics Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Founded in 1998, Altea Therapeutics is developing its PassPort(tm) transdermal drug delivery system to deliver proteins and peptides, small-molecule drugs, genes and vaccines from a skin patch, eliminating the need for invasive needle injection. This breakthrough technology, currently undergoing Phase 1 clinical trials for transdermal delivery of insulin and ...

    SBIR Phase I 2005 Department of Health and Human Services
  4. Diagnostic for Age-Related Macular Degeneration

    SBC: APELIOTUS TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Apeliotus Technologies proposes to develop a commercial diagnostic for the early detection of age-related macular degeneration (ARMD). It relies on a functional test of dark adaptation kinetics (the transition from being light-adapted to being dark-adapted) that has been shown in previous work to detect the onset of ARMD at least four years before it is clinic ...

    SBIR Phase I 2005 Department of Health and Human Services
  5. Flavonoid Compounds for the Prevention of Osteoporosis

    SBC: Aptotec, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Approximately 10 million people in the U.S. are estimated to have osteoporosis, a disease that results in over 1.5 million bone fractures a year. It is now known that the accumulation of fat cells (adipocytes) in bone marrow is a major factor contributing to age-related bone loss. Women with osteoporosis have higher numbers of marrow adipocytes than those wome ...

    SBIR Phase I 2005 Department of Health and Human Services
  6. Microwave remediation of hazardous medical wastes

    SBC: Ashwin-Ushas Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Infectious Medical Wastes, e.g. hospital wastes, represent a major component of hazardous wastes generated in the U.S. annually, with > 4.5 million tons generated from > 7,000 hospitals. Incineration remains the predominant disposal method, with continued problems of environmental pollution, severe local opposition, transportation, high costs associated wit ...

    SBIR Phase I 2005 Department of Health and Human Services
  7. Avian transgenesis via site-directed integration

    SBC: AviGenics Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase II SBIR project describes a novel method to create transgenic poultry that will produce biopharmaceutical proteins in their eggs. Chickens are able to produce large amounts of protein in their eggs at relatively low cost. We seek to harness this capability to synthesize pharmaceutical proteins, such as humanized monoclonal antibodies, that are neede ...

    SBIR Phase II 2005 Department of Health and Human Services
  8. Software for Meta Regression

    SBC: Biostatistical Programming Associates, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Meta analysis plays a key role in setting policy and in planning new research. In gerontology, meta analyses have led to treatment recommendations or new insights in such areas as memory loss with normal aging; identifying, predicting, and treating Alzheimer's disease and dementia; aspirin and the secondary prevention of stroke; drug therapies for osteoporosis; ...

    SBIR Phase II 2005 Department of Health and Human Services
  9. Forest plots for meta analysis

    SBC: Biostatistical Programming Associates, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Meta analysis plays a key role in setting policy and in planning new research. In the field of substance abuse prevention, meta analyses have been used to determine the relative impact of competing treatments for addiction, to estimate prevalence of addiction-related diseases, to plan targeted interventions, to assess the cost-effectiveness of competing treatme ...

    SBIR Phase I 2005 Department of Health and Human Services
  10. SOFTWARE EFFECT ON PROMOTING ADHERENCE TO CHF GUIDELINES

    SBC: COECARE.COM, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Cardiovascular disease continues to be the leading cause of mortality and morbidity in the United States. To assist health care practitioners in their integration of new information into clinical practice, professional organizations such as the American Heart Association, American College of Cardiology, and Heart Failure Society of America have developed clinic ...

    SBIR Phase I 2005 Department of Health and Human Services

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