Award Data

ABSTRACT: The rapid continued development of unmanned air systems (UAS) is enabling new mission types, in-creased mission effects, and increased airman safety. However, these advances also present numerous challenges to airman-machine interaction, tactics development, and defense. The rapid development pace has produced a situation where new technologies are outpacing the knowledge of how best to ...

Ultra-high-performance concrete (UHPC) offers superior properties for structural applications. Existing UHPC design and production methods employ special materials and mixers. This project is developing mix design and fabrication methods for reliable production of UHPC with local materials and facilities. The Phase I project devised material selection criteria, proportioning methods and mixing pro ...

ABSTRACT: Energetic composite materials comprise crystalline energetic particles embedded in a polymer matrix. There is a need to gain insight into the microstructure and damage mechanisms of energetic composites via nondestructive evaluation. Applications of x-ray computed micro-tomography to resolve the microstructure of energetic composites are challenged by the low density gradient between th ...

DESCRIPTION provided by applicant Most samples of chemical interest are complex mixtures making the usual combination of chromatography with mass spectrometry MS a natural choice However the increased demand for chemical analysis by mass spectrometry in many areas of science makes it imperative to increase efficiency of analysis by minimizing sample workup and overall analysis time which ...

DESCRIPTION provided by applicant Dentin hypersensitivity is a painful condition affecting from of the population It is caused by the movement of fluid in the dentinal tubules and can be eliminated by occluding these patent tubules Tooth whitening is a $ billion business in America and is predicted to grow both here and abroad In this grant we propose a treatment for dentin hypers ...

DESCRIPTION provided by applicant Recently we found extensive remodeling of the microvasculature of the retina occurring in some diabetic patients much earlier than expected This provides the potential for novel biomarkers However the equipment is too expensive for most clinics and small practices These early retinal microvascular changes cannot be seen with routine clinical examination o ...

DESCRIPTION provided by applicant In Phase I Biocrede developed a completely new urinary tract silicone Foley catheter with a andgt month shelf life made from a proprietary polymeric formulation to effectively reduce catheter associated urinary tract infections CAUTI via nitric oxide NO release for andgt weeks Key features of the new technology include catheters continuously d ...

DESCRIPTION provided by applicant Up to of low birth weight preterm infants manifest some form of periventricular white matter injury PWMI making it the most common form of brain injury affecting premature infants In the US infants per year are born at risk for PWMI and about children per year will develop PWMI World wide infants will be born each year at ri ...

DESCRIPTION provided by applicant This proposal will develop a new small molecule drug to be advanced into human clinical trials in the chronic post TBI patient who still has chronic cognitive impairments months to years after the initial TBI According to the Centers for Disease Control approximately million Americans suffer from post TBI cognitive impairments This includes people sustai ...

DESCRIPTION provided by applicant The founders of Skeletal Tissue Engineering Laboratory Technologies LLC STEL are researchers at the University of Michigan Our research team has developed an innovative and paradigm shifting approach to ligament tissue engineering and a unique methodology for ACL replacement This tissue engineered ligament technology offers the possibility of radical impr ...