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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. INTELLIGENT MOUTHGUARD FOR MEASURING HEAD IMPACTS IN YOUTH ATHLETES

    SBC: Sportsguard Laboratories, Inc.            Topic: NICHD

    DESCRIPTION provided by applicant With million young athletes participating in contact sports and between to million concussions endured by young athletes yearly in the US subjective concussion identification increases risk of death time lost from school cognitive decline chronic traumatic encephalopathy CTE depression suicide dementia Alzheimerandapos s and Parkinsona ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. TruEnamel: A dental product that treats, protects, desensitizes and whitens teeth

    SBC: TruEnamel, LLC            Topic: NIDCR

    DESCRIPTION provided by applicant Dentin hypersensitivity is a painful condition affecting from of the population It is caused by the movement of fluid in the dentinal tubules and can be eliminated by occluding these patent tubules Tooth whitening is a $ billion business in America and is predicted to grow both here and abroad In this grant we propose a treatment for dentin hypers ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. IRE1 alpha inhibitors for type 2 diabetes

    SBC: Optikira, LLC            Topic: 200

    DESCRIPTION provided by applicant The American Diabetes Association has declared type diabetes T D a public health crisis T D begins as a state of compensated insulin resistance frank disease develops when of insulin producing pancreatic islet cells of affected individuals undergo cell death Endoplasmic reticulum ER stress has emerged as a central underlying mechanism that drive ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. PDE4B Inhibitors for Treating Brain Injury

    SBC: TETRA DISCOVERY PARTNERS, INC.            Topic: 106

    DESCRIPTION provided by applicant This proposal will develop a new small molecule drug to be advanced into human clinical trials in the chronic post TBI patient who still has chronic cognitive impairments months to years after the initial TBI According to the Centers for Disease Control approximately million Americans suffer from post TBI cognitive impairments This includes people sustai ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Validation and Cryopreservation of Ligament Engineered from Human Bone Marrow

    SBC: STEL Technologies, LLC            Topic: NIAMS

    DESCRIPTION provided by applicant The founders of Skeletal Tissue Engineering Laboratory Technologies LLC STEL are researchers at the University of Michigan Our research team has developed an innovative and paradigm shifting approach to ligament tissue engineering and a unique methodology for ACL replacement This tissue engineered ligament technology offers the possibility of radical impr ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. S-Nitrosothiol-Based Rinse/Aerosol Solutions For Treatment/Prevention of Rhinosinusitis

    SBC: NOTA Laboratories LLC            Topic: NIAID

    DESCRIPTION provided by applicant The purpose of the research being proposed is to develop a highly effective nasal rinse that can treat chronic rhinosinusitis CRS in an entirely new way Often CRS is overlooked because it is rarely life threatening CRS is estimated to affect an astounding of the US population with direct costs exceeding $ billion annually and additionally causing ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Family Supportive Supervisor Training and Workplace Assessment Tool

    SBC: WORK LIFE HELP, INC.            Topic: NIA

    DESCRIPTION provided by applicant Managing the demands of work and personal life is a major stressor affecting employees yet there are virtually no evidence based workplace supervisory training interventions to address this critical public health concern Research has shown work family conflict can affect employeesandapos health workplace productivity family interactions and safety and wel ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Improving Outcomes for Mechanically Ventilated Patients with the Digital EZ Board

    SBC: VIDATAK, LLC            Topic: 600

    DESCRIPTION provided by applicant Effective communication between patients and healthcare professionals is essential to achieve positive clinical outcomes Patients who are unable to communicate effectively e g patients with limited English proficiency LEP those who are hearing impaired aphasic or have oral tracheal intubation experience extreme frustration panic anxiety sleeplessne ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Modeling and Simulation for Design, Development, Testing and Evaluation of Autonomous Multi-Agent Models

    SBC: Soar Technology, Inc.            Topic: AF15AT14

    ABSTRACT: The rapid continued development of unmanned air systems (UAS) is enabling new mission types, in-creased mission effects, and increased airman safety. However, these advances also present numerous challenges to airman-machine interaction, tactics development, and defense. The rapid development pace has produced a situation where new technologies are outpacing the knowledge of how best to ...

    STTR Phase I 2015 Department of DefenseAir Force
  10. Interface for the collection, analysis, and visualization of simulation performance data

    SBC: Perduco Group, Inc., The            Topic: AF15AT14

    ABSTRACT: To complement capabilities of future autonomous systems, the Air Force requires interoperable tools & methodologies to design, verify, validate, assess & operate human-machine system interactions associated with autonomous and manned systems integration. Often the human performance measures and status of each simulation is reported independently making it challenging to analyze the data. ...

    STTR Phase I 2015 Department of DefenseAir Force

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