Award Data

ABSTRACT:Recent technical demonstrations in hostile fire sensing and classification have highlighted the use of costly cryogenically-cooled electro-optical sensors.While capable, these types of sensors come with a higher initial purchase price as well as high life cycle costs per platform.This activity will implement a broad area hostile fire sensing architecture that uses lower cost discrete sens ...

e Tect has created a medication adherence monitoring system called ID Cap consisting of a tag smaller than the size of a postage stamp that can be wrapped around a capsule or attached to a pill When the tagged medication is ingested it activates and sends a signal to a reader worn on the arm The reader relays the signals securely to a remote database enabling accurate medication adherence monit ...

ABSTRACT:The objective of this proposal is to design an inexpensive hypersonic test article with an associated instrumentation package capable of providing measurements necessary for advancing the understanding of aerothermal behavior in the hypersonic flow regime. Significant advances and accuracy validation within multi-physics computational science and engineering (CSE) toolsets (such as comput ...

ABSTRACT:The warfighter needs an accurate and reliable source of Position, Navigation, and Timing (PNT) when GPS is not available. Fortunately, technical advances in navigation sensors and algorithms can reduce dependence on the venerable, yet vulnerable, GPS system. Inertial sensors are becoming increasingly smaller and more accurate. Low cost, powerful embedded computing platforms enable real ti ...

TBD

DESCRIPTION provided by applicant The tumor suppressor Adenomatous Polyposis Coli APC directs degradation of catenin a central signaling protein in the WNT pathway Germline loss of function mutations in APC activate WNT signaling and underlie the inherited colorectal cancer predisposition syndrome Familial Adenomatous Polyposis FAP an orphan disease while somatic mutations lead to spo ...

DESCRIPTION provided by applicant Influenza is a leading cause of death and morbidity in the US resulting in up to deaths hospitalizations and andgt $ billion in expenses per year Current antivirals incur high resistance rates and have low efficacy so there is a crucial need to develop better approaches to protect from seasonal influenza and future pandemics We aim to ...

DESCRIPTION provided by applicant The emerging field of stem cell therapy has the potential to transform medicine forever However a major bottleneck for bringing stem cell therapies to the patient is the lack of adequate in vitro assays for the study of stem cell quality Critical test criteria are efficacy pluripotency prior to the differentiation process and safety lack of tumorigenicity ...

DESCRIPTIONprovided by applicantThe primary goal of this proposal is to develop and finalize configuration of a rapid molecular diagnostics test to predict antibiotic resistance of th major human uropathogensEscherichia coliKlebsiella pneumoniaeEnterobacter spp and Pmirabilisby determining the sub species clonal identityclonotypeof the infecting bacteria directly from urine samplesCurrentlythe emp ...

DESCRIPTION provided by applicant Cardiovascular diseases and Asthma affects between and million people in the United States including million children during the past years its incidence worldwide has doubled Asthma is responsible for million person days of restricted activity and deaths per year amounting to $ billion in direct heath related costs there is uncertainty about the specific factors ...