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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A FAP-Activated Proteasome Inhibitor for Killing Solid Tumors
SBC: ARISAPH PHARMACEUTICALS, INC. Topic: 102DESCRIPTION provided by applicant Cancer is the second leading cause of death after heart disease in the US Chemotherapy is a mainstay of treatment after surgical removal of tumors but the balance of clinical benefit versus disabling or life threatening side effects is often uncertain Genotyping of cancers to identify mutated oncogenes has enabled an era of targeted therapy Drugs targeting ...
STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health -
A New MicroRNA-1291 Replacement Therapy for Pancreatic Cancer Disease
SBC: MIRNA THERAPEUTICS, INC. Topic: NIAAADESCRIPTION (provided by applicant): Pancreatic cancer is the fourth leading cause of cancer-related death in the United States. There is a clear need for more effective therapies to treat deadly pancreatic cancer disease. MicroRNAs (miRNA or miR) are a large group of short, noncoding RNAs that control posttranscriptional gene expression in human cells, and there is increasing evidence for the exi ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
A novel 3D cell culture human uterine contractility assay for high-throughput scr
SBC: CHEMOSEN3D INC Topic: NICHDDESCRIPTION (provided by applicant): Several disorders in reproductive medicine are results of changes in smooth muscle contractile activity. Increased myometrial contraction can lead to preterm labor, which affects 12% of the US population. However, the mechanisms involved in the transition from uterine quiescence to contractility at the onset of labor are not well-known. As a result, the managem ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
A Novel Technology to Produce Yb:Sr-FAP Transparent Laser Host Ceramics in Non-Isotropic Materials
SBC: TEXAS BIOCHEMICALS INC Topic: AF14AT26ABSTRACT: To fabricate transparent ceramics composed of anisotropic laser gain media, the crystal orientations of micro-domains should be aligned identically. Current method involve application of high magnetic field. Texas Biochemicals Inc. recently developed a novel technology to produce faceted hexagonal prism c axis oriented Yb: Sr-FAP [Yb: Sr5(PO4)3F nanocrystallites and sintered into transp ...
STTR Phase I 2014 Department of DefenseAir Force -
A smart needle guide template for MRI-guided transperineal prostate biopsy
SBC: PHYSICAL SCIENCES INC. Topic: NCIDESCRIPTION (provided by applicant): Physical Sciences Inc. (PSI) and the Surgical Navigation and Robotics Laboratory (SNR) at Brigham and Women's Hospital (BWH) propose to develop and test a Smart Template to guide transperineal targeted prostate biopsiesand subsequent therapy under magnetic resonance imaging (MRI). The project aims to solve the problem of poor diagnostic yield in prostate b ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
AutoRegister: A system for enhancing the accuracy of tumor change detection
SBC: CORTICOMETRICS LLC Topic: NCIDESCRIPTION (provided by applicant): This project proposes to build an integrated software-based system for enhancing the accuracy of tumor change detection. The intent of the system, called AutoRegister, which is to be deployed on a clinical magnetic resonance imaging (MRI) scanner platform, is to automate the alignment of a patient's brain scan with that of a prior scan, such that subseque ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Brain penetrant Hsp90 inhibitors for Alzheimer's disease
SBC: YUMA THERAPEUTICS CORPORAITON Topic: NIADESCRIPTION provided by applicant Neurodegeneration in Alzheimerandapos s disease AD may result from deposition of A as plaques in brain tissue However less effort has been made to elucidate the role of tau containing neurofibrillary tangles NFTs in AD Accumulating evidence suggests that tau containing NFTs is an important component in the initiation and progression of AD and other neu ...
STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health -
Compact CMOS-Compatible Optical Transceiver
SBC: PHYSICAL SCIENCES INC. Topic: AF14AT13ABSTRACT: Close integration of photonic devices with silicon complementary metal-oxide semiconductor (CMOS) electronics can yield significant performance improvements in many applications. The recent development of novel integrated structures in silicon including waveguides, resonators, and photodetectors will enable dramatic reductions in size, weight, and power for components implementing compl ...
STTR Phase I 2014 Department of DefenseAir Force -
Decision Making under Uncertainty for Dynamic Spectrum Access
SBC: INFOBEYOND TECHNOLOGY LLC Topic: AF13AT02ABSTRACT: Due to scarcity of spectrum, Dynamic Spectrum Access (DSA) becomes a needed technology to improve the utilization of electromagnetic spectrum for DoD satellite communication. However, current DSA approaches are developed for terrestrial communications without addressing the unique challenges for SATCOM environments such as error-prone spectrum sensing, high mobility, and large coverage. ...
STTR Phase I 2014 Department of DefenseAir Force -
Developing Inhibitors of the STARS/SRF Pathway for Treatment of Type 2 Diabetes
SBC: Jenesis Biosciences LLC Topic: NIDDKDESCRIPTION (provided by applicant): Type 2 diabetes (T2D) has reached epidemic proportions in the United States, affecting an estimated 8.3% of the population. Unfortunately, the majority of individuals with diabetes continue to have suboptimal control ofglucose, therefore new and improved approaches to prevention and treatment are sorely needed. Dr. Mary Elizabeth Patti's laboratory at the ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health