Award Data

We propose a platform for aerial environmental monitoring based on the integration of two advanced technologies for the first time: a lightweight, flying robotic platform capable of hovering and swarming, and a compact, low-power chemical sensor platform called the Molecular Property Spectrometer (MPS): a robust, low-cost, silicon-chip-based micro-electro-mechanical system (MEMS) that has been use ...

ABSTRACT: UltraHiNet, LLC (UHN) proposes to develop a prototype next generation tracking architecture which exploits wide area motion imagery (WAMI) systems and leverages projected heterogeneous high performance computing (HPC) architectures for on-board and ground-based processing of vehicle and dismount targets for urban surveillance. Our research team will focus on the following goals: 1. Dev ...

ABSTRACT: Information systems continue to progress in terms of collecting, characterizing and assessing information. While this evolution has provided unprecedented intelligence capability to the U.S. and our allies, it has also raised unique challenges in the area of information security and disclosure risks. In particular, the intelligence community (IC) currently lacks the ability to understan ...

ABSTRACT: The ability to obtain time-resolved, direct wall shear stress measurement is an important asset to aerodynamic research, flow control and to enhance the fundamental understanding of the turbulent boundary layer. Due to a lack of reliable and affordable skin friction sensors, existing indirect methods are used to measure wall shear stress but their usefulness is limited since prior kno ...

The rapid ascent and adoption of social media as the dominant form of communication has led to significant analysis challenges. In particular, there is a gap in theoretically informed methods to analyze data mined and collected from social media. One primary cause of this gap is the lack of fusing structural sources of information (e.g. social network topology) with non-structural sources (message ...

MTI-101 is a cyclic beta-hairpin peptide that binds CD44 with high affinity and kills multiple myeloma cell lines in vitro and blocks the growth of myeloma tumors in 2 different murine models. This interaction of MTI-101 with the surface of MM cells causesprogrammed cell necrosis, whereas all approved MM drugs cause apoptosis and so the novel mechanism of MTI-101 or MTI-like compounds makes it esp ...

PROJECT SUMMARY Spinal cord injury (SCI) is a complex and devastating clinical condition mediated by proinflammatory cytokines that produce neuronal loss, axonal destruction, and demyelination during the secondary injury cascade. There are currently no proven therapies targeting posttraumatic inflammation that have been shown to have clinical value. We have previously shown that central nervous sy ...

DESCRIPTION provided by applicant Duchenne Muscular Dystrophy DMD is a fatal muscle disease affecting in every male births DMD results from mutations in the gene encoding the dystrophin a kDa scaffolding protein responsible for providing a mechanical link between the muscle fiber actin cytoskeleton and a transmembrane protein complex called the dystrophin associated glycoprotein ...

DESCRIPTION provided by applicant The number of Lyme disease cases in the US has been recently estimated by the CDC at cases year This is major public health concern Currently available diagnostics rely on detection of the antibody response serology to Borrelia burgdorferi the causative agent of Lyme disease However serological tests are not accurate during the early stages of Ly ...

DESCRIPTION (provided by applicant): Sarcopenia, or the deterioration of muscle health with advancing age, is a major public health concern in the developed world. Some of the most important factors underlying the development of sarcopenia are age- relatedchange in muscle composition, including the replacement of muscle fibers by fat and the loss of muscle force production. Declines in muscle comp ...