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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Pcmcia Ecg Monitoring System for Handheld Computers

    SBC: ADVANCED MEDICAL ELECTRONICS CORPORATION            Topic: N/A

    An ECC monitoring system in the form of a miniature Personal Computer Memory Card International Ass(PCMCIA) card is proposed. PCMCIA is a standard for credit card-sized ( 5mm x 86mm x 54 mm) peripherdesigned to use with notebook and handheld computers. The user can quickly remove and add these cardportable computers. Cards are manufactured that add I/0 devices to the computer, such as modems, loc( ...

    SBIR Phase I 1995 Department of Health and Human Services
  2. Wireless Sleep Disorder Monitoring System

    SBC: ADVANCED MEDICAL ELECTRONICS CORPORATION            Topic: N/A

    N/A

    SBIR Phase I 1995 Department of Health and Human Services
  3. Long Term UV-B Record Keeping of Outdoor Workers

    SBC: ADVANCED MEDICAL ELECTRONICS CORPORATION            Topic: N/A

    N/A

    SBIR Phase I 1995 Department of Health and Human Services
  4. Hematopoietic Stem Cell Enrichment by Negative Selection

    SBC: BIOERGONOMICS, INC.            Topic: N/A

    Stem cells are the agents of hematopoietic reconstitution in bone marrow transplantation and are atherapy. This proposal is to facilitate human stem cell research by providing a rapid, high yield syrecovering stem cells from bone marrow, cord blood or peripheral blood sources. This system consistsof specific sequential depletions of non-stem cell components using an erythrocyte precipitation bufim ...

    SBIR Phase I 1995 Department of Health and Human Services
  5. Surface Modification to Improve Breast Prostheses

    SBC: SURMODICS, INC.            Topic: N/A

    There are currently no rapid and reliable in vitro assays that measure the metastatic activity of cells. In this project, we will develop an improved Boyden chamber chemoinvasion assay. The Boyden chamber chemoinvasion assay will utilize Transwell¿ membranes with a defined basement membrane overlayer that will allow in vitro assays for metastatic cells to be conducted with greater speed, reproduc ...

    SBIR Phase II 1995 Department of Health and Human Services
  6. Photoaffinity Immobilization of Fusion Proteins

    SBC: SURMODICS, INC.            Topic: N/A

    This proposal presents an approach to resolving a critical and enduring obstacle to developing biosfor the timely detection of toxic and infectious agents. We will develop a passivated sensor surfaceuniquely with the specific binding protein in its crude source solution and, upon activation by lighprotein functionally oriented in a stabilizing, biomolecule-compatible environment. A trifunctionalde ...

    SBIR Phase I 1995 Department of Health and Human Services
  7. Dental Implant Coatings to Improve Gingival Attachment

    SBC: SURMODICS, INC.            Topic: N/A

    We will improve the bonding of gingival tissue to osseointegrated dental implants by coating the peportion of implants with extracellular matrix (ECM) proteins. ECM proteins, which will be covalentlytransgingival implant surfaces using patented BSI photochemistry, are expected to improve the attachgingival fibroblasts and epithelial cells. Improved bonding by gingival connective tissue is expecteo ...

    SBIR Phase I 1995 Department of Health and Human Services
  8. Enzyme Immobilization for Extracorporeal Detoxification

    SBC: SURMODICS, INC.            Topic: N/A

    Successful photoimmobilization of active, stable heparinase on surface modified polymeric microsphean important technology for removal from blood of heparin required during hemodialysis. cardiopulmonvascular surgery. The availability of this technology for heparin removal would eliminate the requirof heparin by the addition of a compound which has deleterious side effects (protamine). The improvet ...

    SBIR Phase I 1995 Department of Health and Human Services
  9. Photocrosslinkable Polymers for Islet Encapsulation

    SBC: SURMODICS, INC.            Topic: N/A

    Insulin-dependent diabetes mellitus affects millions of persons in the U.S. Despite years of intenseffectiveness of current therapeutic regimens remains limited due to the difficulty of duplicating thealthy pancreas. A potential method of treating this disease is the transplantation of allogenic orLangerhans. The most significant obstacle to the development of this approach is the immune rejectioI ...

    SBIR Phase I 1995 Department of Health and Human Services
  10. Vascular Graft Coating for Transmural Endothelialization

    SBC: SURMODICS, INC.            Topic: N/A

    There are currently no artificial polymeric vascular grafts with an internal diameter of less thanadequate long-term patency, with occlusion being due to a combination of thrombus formation and intiproject will improve the patency of such grafts by promoting rapid and stable transmural endothelialendothelialization process, capillaries from surrounding tissue invade the wall porosity of grafts ace ...

    SBIR Phase I 1995 Department of Health and Human Services

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