Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Monitored Breathing Awareness Therapy for Insomnia Disorder in Older Adults

    SBC: ADVANCED MEDICAL ELECTRONICS CORPORATION            Topic: NIA

    Insomnia of sufficient clinical severity to meet diagnostic criteria is present in approximatelyof older adultsnearlymillion individuals in the US aloneIf left untreatedit can lead to increased rates of depressioncognitive impairmentand cardiovascular diseaseTreatment relies on pharmacotherapysuch as sedativehypnotic therapywhich is associated with an increased risk of fallsaccidentsand deliriumco ...

    STTR Phase II 2017 Department of Health and Human Services
  2. Advanced Hit Detection Systems

    SBC: FREENT TECHNOLOGIES, INC.            Topic: MDA13015

    FreEnt Technologies, Inc. (FreEnt) and Johns Hopkins Universitys Applied Physics Laboratory (APL) are proposing a multiple-hit detection sensor called the Optical Lethality Measurement System (OLMS). This system is based on the Planar Optical Penetration Sensor (POPS) technology (originally developed and patented by APL) and prior art associated with the Blast Initiation Detector (BID). The BID is ...

    STTR Phase II 2017 Department of DefenseMissile Defense Agency
  3. Validation of Novel Therapeutic Approach for Cryptococcal Meningitis

    SBC: Minnetronix Medical, Inc.            Topic: NIAID

    Validation of a Novel Therapeutic Approach for Cryptococcal Meningitis PILadShivanand and McCabeAaron Project Summary When Cryptococcus is manifested as cryptococcal meningitisCMit creates a large burden of mortality and morbidity to the patient and is very difficult for the clinician to treatThere are now an estimatedUS cases andcases of CM worldwide annuallywith estimated mortality ofper yearCM ...

    STTR Phase II 2017 Department of Health and Human Services
  4. Commercialization of a Novel Therapeutic for Alzheimer's Disease

    SBC: CoPlex Therapeutics, LLC            Topic: NIA

    ABSTRACT Traditional mon therapeutictarget driven approaches to drug development for Alzheimer s diseaseADare becoming increasingly expensive and in many cases disappointingly unsuccessfulBased on preliminary in vitro and in vivo studies we have identified a novel small moleculemethyldimethyloxodihydrobenzo cnaphthyridinecarboxylateBNCthat significantly decreases neuroinflammation and production o ...

    STTR Phase II 2017 Department of Health and Human Services
  5. System of Systems Control Interactions

    SBC: GTD Unlimited LLC            Topic: MDA15T002

    In this research effort, the GTD team will design tools for efficiently specifying, representing, and analyzing the interactions between control systems in System of Systems (SoS). Three approaches will be considered and integrated. The first two are based in the rigorous application of H_8 control theory to the SoS design problem. The third will use complexity measures to generate a metric that c ...

    STTR Phase II 2017 Department of DefenseMissile Defense Agency
  6. veriScan

    SBC: Sentar, Inc.            Topic: OSD06SP2

    The goal of the Information Assurance Run-time Auditing (IARA) Phase I project was to provide a framework that promotes the specification of software system monitoring, audit, analysis, and threat mitigation capabilities in large scale software intensive systems (LSSIS). IARA was designed to promote software assurance by incorporating novel tools that help certify the operations of untrusted soft ...

    STTR Phase II 2017 Department of DefenseMissile Defense Agency
  7. RF-IR Data Fusion

    SBC: Decibel Research, Inc.            Topic: MDA12T002

    deciBel Research, Inc. and the Electrical Engineering Department at the University of Mississippi - the deciBel Team - proposes to continue to develop and mature threat physics based classification, track association/track correlation, and dynamic attributes determination threat characterization algorithms that effectively and efficiently fuse data from multiple sensors. The classification algorit ...

    STTR Phase II 2017 Department of DefenseMissile Defense Agency
  8. Measurement and Modeling of Surface Coking in Fuel-Film Cooled Liquid Rocket Engines

    SBC: CFD Research Corporation            Topic: AF15AT21

    Designing an efficient and effective film cooling system to protect critical components of modern rocket engines requires a significant number of problems and challenges to be addressed. Complicating the already difficult hydrodynamic challenges, thermal and/or catalytic cracking of hydrocarbon fuels is always accompanied with coke formation. Coke deposits on combustor and nozzle walls reduce heat ...

    STTR Phase II 2017 Department of DefenseAir Force
  9. Development of Adaptive Closure Models for Large Eddy Simulations of Lean Blow-Out Conditions

    SBC: CFD Research Corporation            Topic: AF16AT14

    The objective of the proposed Phase II effort is to establish fundamental understanding of combustion-physical mechanisms leading to blowout, the critical evaluation of model limitations in predicting these blowout processes and the development of an improved combustion model to enable the prediction of lean blowout (LBO) in swirl-stabilized combustors. For this, high-resolution numerical simulati ...

    STTR Phase II 2017 Department of DefenseAir Force
  10. Vastly improved influenza diagnostics through the development of a handheld thermal contrast reader

    SBC: Vigilant Diagnostics, LLC            Topic: 600

    VIGILANT DIAGNOSTICS NIAID NIH STTR Phase I Application Vastly improved influenza diagnostics through the development of a portable thermal contrast reader PROJECT SUMMARY ABSTRACT Despite recent advances in rapid influenza diagnostic tests false negatives stemming from poor sensitivity contribute to nosocomial transmission and prevent thousands from receiving appropriate antiviral treatment A ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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