Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. An Automated System to Locate Items Misplaced by Persons with Dementia in a Care Facility

    SBC: Applied Universal Dynamics, Corp.            Topic: NIA

    Abstract This application responds directly to the purpose of the PARSBIR Funding Opportunity AnnouncementFOAThis project will develop an assistive system for caregivers of persons with dementiaPWDto locate items that have been misplaced by PWDA PWD who misplaces objects can create feelings of anxiety and frustration for both the PWD and the caregiversThe PWD can leave an object in a very unusual ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Social Assistive Robot Interface for People with Alzheimer's and Other Dementias to Aid in Care Management

    SBC: ADVANCED MEDICAL ELECTRONICS CORPORATION            Topic: NIA

    Project Summary Abstract Advanced Medical Electronics Corporation and our partners propose to develop a Socially Assistive RobotSARsystem for persons with dementiaPWDmild cognitive impairmentAlzheimerandapos s diseaseor other dementiaswho are living in assisted living facilitiesThe proposed system uses Augmented IntelligenceAIto communicate with the PWD in natural languageThe systemandapos s goals ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Balloon Angioplasty Inflation Device

    SBC: Minnesota HealthSolutions Corporation            Topic: NIA

    Project Summary Abstract We propose the development of a novel balloon angioplasty inflation device for improving the safety and efficacy of balloon angioplastyAtherosclerosis is associated with coronary artery diseaseischemic stroke and peripheral arterial diseasePercutaneous balloon angioplastyoften in conjunction with stent device deploymenthas been associated with prolonged survivalincreased q ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Perfusion decellularization and recellularization for the creation of a bioengineered transplantable liver

    SBC: Miromatrix Medical Inc.            Topic: 300

    ABSTRACT Liver transplantation currently represents the only treatment for end stage liver diseaseESLDtheth most frequent cause of death in the United StatesUSEfforts to overcome the chronic shortage of transplantable human livers include attempts at alternative organ procurement and replacement strategiesThe most promising approach to date that provides the appropriate matrix composition and supp ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Clinical evaluation of combination oncolytic viro-immunotherapy for solid tumors

    SBC: Vyriad, Inc.            Topic: 102

    PROJECT SUMMARY ABSTRACT Non small cell lung cancer NSCLC and hepatocellular carcinoma HCC are leading cause of cancer death globally Immune checkpoint inhibitors CPIs which block tumor immune evasion signals and activate T cell mediated antitumor immunity have demonstrated clinical efficacy and are approved for several cancers including NSCLC and HCC Despite this broad spectrum of activity less t ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Cerebral Spinal Fluid Shunt System with Dual Lumen Distal Catheter Redundancy to Minimize Revision Surgery

    SBC: Cerovations, LLC            Topic: 102

    Abstract SignificanceCerebral spinal fluidCSFshunt failure resulting in revision surgery is a major problem for hydrocephalus patientsUp toof shunts fail within two years of implantA NIH funded expert panel has identified improved shunt design as a research priority to improve hydrocephalic patient outcomesOcclusion is the most common CSF shunt failure modeand little has changed with shunt failure ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Fluorescence lifetime platform to discover small-molecule inhibitors of tau and alpha-synuclein oligomerization.

    SBC: Photonic Pharma LLC            Topic: NIA

    Project SummaryIn this Phase I STTR projectPhotonic Pharma LLCPPin collaboration with the University of MinnesotaUMNwill establish a technology platform for high throughput screeningHTSto discover small molecule inhibitors of pathological self association of tau andsynucleinsynOligomers of these proteins are implicated in the pathologyseverityand progression of Alzheimer s diseaseADand Alzheimer s ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Development of a Bariatric Mannequin System to Enable Realistic Examination Simulations of Obese Patients

    SBC: Innovative Design Labs Inc.            Topic: 300

    Project Summary Abstract The proposed project focuses on creating a bariatric mannequin simulator to educate healthcare students on proper techniques specific and specialized to bariatric patient careSignificanceObesity is one of the world s most significant and growing health problemsMore thaninadults are overweight or have obesity and obese patients have a greater likelihood of requiring clinica ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Targeted Lead (Pb) Removal for Drinking Water Purification Using INCION

    SBC: PowerTech Water, Inc.            Topic: NIEHS

    PROJECT SUMMARY Lead contamination in drinking water is a pervasive health problem across the USChildren are especially vulnerable to lead poisoningwhich can have permanent detrimental effects on brain developmentDespite corrosion prevention measures taken by public water authoritieslead concentrations in drinking water are routinely elevated nationwideThe Environmental Protection AgencyEPAestabli ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Development and Characterization of a Preclinical Swine Model of Osteogenesis Imperfecta

    SBC: Recombinetics, Inc.            Topic: NIDCR

    PROJECT SUMMARY Osteogenesis imperfectaOIalso known asbrittle bone diseaseis a genetic disease in which patients have defects in the formationstructureor strength of their bonescausing them to break easilyOI patients exhibit impaired tissue development and bone regeneration due to inherited mutations in one of the collagen genesleading to skeletal defectsbone fragilitydentinogenesis imperfectahear ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government