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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Validation of Novel Therapeutic Approach for Cryptococcal Meningitis
SBC: Minnetronix Medical, Inc. Topic: NIAIDValidation of a Novel Therapeutic Approach for Cryptococcal Meningitis PILadShivanand and McCabeAaron Project Summary When Cryptococcus is manifested as cryptococcal meningitisCMit creates a large burden of mortality and morbidity to the patient and is very difficult for the clinician to treatThere are now an estimatedUS cases andcases of CM worldwide annuallywith estimated mortality ofper yearCM ...
STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
AutoRegister: A system for enhancing the accuracy of tumor change detection
SBC: CORTICOMETRICS LLC Topic: 102PROJECT SUMMARY This project proposes to continue the development of AutoRegisterTMan integrated software based system for enhancing the accuracy of tumor change detectionThe intent of the system is to automate the alignment of a patient s brain scan with that of a prior scan such that subsequent offline tumor measurements do not have error introduced solely by differing slice orientationsWhile si ...
STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
Clinical Translation of Augmented Reality Visualization for Laparoscopic Surgery
SBC: IGI TECHNOLOGIES, INC Topic: 102The overall objective of the proposed research is to develop and conduct clinical translation of a novel visualization technology that provides minimally invasive surgeons the ability to visualize normally invisible internal anatomy together with organ surfacesThe technology addresses a long standing need in minimally invasive laparoscopic surgery to see inside and around a structure before dissec ...
STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
DEVELOPMENT OF A NOVEL ANTIVIRAL TO TREAT AND PREVENT ACYCLOVIR RESISTANCE IN HUMAN OCULAR HERPES KERATITIS
SBC: FOX CHASE CHEMICAL DIVERSITY CENTER INC. Topic: NABSTRACT Infection of the eye by Herpes Simplex Virus HSV can result in Herpes Keratitis HK which is the leading cause of corneal blindness worldwide In the U S nearly individuals experience ocular herpes infections that are often recurrent and culminate in progressive corneal scarring and loss of vision The gold standard of care for HK is treatment with Acyclovir ACV that t ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Infection Site Targeted Antitoxin Antibody (ISTAb) against Bacillus anthracis
SBC: Integrated Biotherapeutics, Inc. Topic: rProject Summary The Gram positive bacterium Bacillus anthracis is a very strong candidate for potential bioweaponizationand believed to have actually been weaponized by the former Soviet UnionAnthrax spores are readily found in nature or produced in the laboratoryare resistant to harsh conditionsand can survive for a long time in the environmentThe microscopic spores could be formulated in powder ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Tools for site specific antibody immobilization for immunoassays
SBC: ALPHATHERA Topic: NAntibodies most commonly Immunoglobulin Gs IgGs are widely used in research and diagnostic assays due to their wide array of targets high specificity and proven efficacy In many of these immunoassays e g ELISAandapos s biosensors etc antibodies must be immobilized onto surfaces The sensitivity stability and longevity of antibodies used in this context are highly dependent on orien ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
In Vivo Editing for Hemophilia Gene Therapy
SBC: GENVEC, INC. Topic: 100Project Summary The exceptional promise of gene therapy for hemophilia has been shown in recent studies that result in long term correction of factor IX deficiency via hepatic transduction with an adeno associated vector AAV In spite of this watershed event in the history of the gene therapy field there presently exist barriers to the fullest implementation of hemophilia gene therapy The li ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Broadly Protective Bispecific Antibodies for Treatment of Ebola Virus Disease
SBC: Integrated Biotherapeutics, Inc. Topic: NIAIDPROJECT SUMMARY The family of Filoviridae consisting of five ebolaviruses and two marburgviruses are causative agents of severe hemorrhagic fever with human case fatality rates ofTheepidemic of Ebola virus disease in West Africa was unprecedented both in geographic scope and size and highlighted the extent of the threat filoviruses could pose to global public health and the urgent need for develop ...
STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
Development Characterization and Commercialization of a Viably Frozen Patient Inclusive Hepatocellular Carcinoma Tumor Bank
SBC: Woodland Pharmaceuticals LLC Topic: 103Abstract Hepatocellular carcinoma HCC is a disease of growing incidence globally including in the US by per year With the recent success of anti viral therapies the etiology of HCC in the American population is projected to shift from viral HBV HCV hepatitis to primarily fatty liver disease in the near future Currently only one effective systemic therapy has been developed for HCC ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Trans‐nasal delivery of chemotherapy to glioblastoma using magnetic nanoparticles and magnetic focusing
SBC: WEINBERG MEDICAL PHYSICS, INC. Topic: 102Abstract Glioblastoma multiforme GBM is the deadliest form of brain tumor The current treatment includes a combination of surgical resection chemotherapy radiation and electrical disruption of mitosis has only extended survival to approximately to years Preliminary pre clinical findings suggest the potential effectiveness of the candidate drug cyclopamine However the drug is toxic to ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health