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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Coils for Human Whole Body Imaging at 7T

    SBC: LIFE SERVICES L.L.C.            Topic: NIBIB

    DESCRIPTION provided by applicant For this Phase II STTR proposal the investigators plan to develop and commercialize the radiofrequency RF coil technology to make T body MRI possible and to translate this new technology to vastly improve T clinical MRI as well In the Phase I project leading to this proposal all specific aims were accomplished to demonstrate the feasibility of safely an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. A Novel Vaccine to Prevent Urinary Tract Infections

    SBC: SYNTIRON, LLC            Topic: NIAID

    DESCRIPTION provided by applicant Urinary tract infections UTIs caused by extraintestinal pathogenic E coli ExPEC account for nearly million emergency room visits and hospitalizations per year for women in the U S alone Approximately half of all women will experience a symptomatic UTI in their lifetime and will experience a recurrence within to months While several ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Therapy and Prophylaxis for Genital Tract Infection

    SBC: THERAPYX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Genital tract infection with Neisseria gonorrhoeae gonorrhea does not induce a state of specific protective immunity and can be acquired repeatedly Despite public health measures the disease persists at an unacceptably high frequency there is no vaccine against it and resistance even to the latest generations of antibiotics continues to emerge Recent fin ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a Clinically Viable Pattern Recognition Embedded System

    SBC: Coapt LLC            Topic: NICHD

    DESCRIPTION provided by applicant Pattern recognition PR myoelectric control systems can dramatically improve an amputee patientandapos s control of a powered prosthesis but they have not been made commercially available Coapt LLC is a start up stage company that has initiated a controlled commercial release of PR myoelectric control for the benefit of upper limb amputees The controlle ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. IntelliWheels: The Automatic Transmission for Manually Propelled Wheelchairs

    SBC: IntelliWheels, Inc.            Topic: 22

    DESCRIPTION provided by applicant IntelliWheels automatic gear shifting wheels represent a significant paradigm shift as the first ultra light affordable and intuitive way to mke pushing a wheelchair easier The manual wheelchair user mWCU still pushes the hand rims in any direction however the hand rims drive the transmissions located in each wheel hub which in turn drive the wheels ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Development of Novel S. aureus Antibiotics with Reduced Resistance Susceptibility

    SBC: NOVALEX THERAPEUTICS, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Widespread antibiotic use has accelerated S aureus resistance to almost all marketed antibiotic classes including beta lactams fluoroquinolones macrolides aminoglycosides tetracyclines as well as the newer linezolid and daptomycin Methicillin resistant S aureus MRSA is an increasing public health threat with deaths from MRSA infections already compar ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Development of broad spectrum Hepatitis C Virus NS3/4A protease inhibitors

    SBC: NOVALEX THERAPEUTICS, INC.            Topic: NIAID

    DESCRIPTION provided by applicant This is a collaborative proposal to develop inhibitors with reduced susceptibility to resistance and improved genotype spectrum of activity against the NS A protease of the Hepatitis C virus HCV Over three percent of the worldandapos s population is infected with the hepatitis C virus HCV Unfortunately the current best treatment is still quite challeng ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Pediatric Anxiety Intervention with an Entertaining Video Game

    SBC: ADVANCED MEDICAL ELECTRONICS CORPORATION            Topic: 104

    DESCRIPTION provided by applicant This project will develop an immersive video game for children with social anxiety disorder SAD The video game will serve as a vehicle to deliver evidence based Cognitive Behavioral Therapy CBT in an engaging manner so that its target audience perceives it as entertainment rather than therapy Social interactions are crucial to success in all areas of life ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Catheter for Large Volume Intraparenchymal Brain Therapies

    SBC: TWIN STAR TDS, LLC            Topic: 105

    DESCRIPTION provided by applicant Neurodegenerative and malignant diseases of the central nervous system affect millions of Americans These diseases are often devastating and difficult to treat and effective drug delivery remains a significant challenge Infusion of drugs nto the brain parenchyma using convection enhanced delivery CED allows direct treatment of lesions circumventing the bl ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. At Home Gait Monitoring of Cerebral Palsy to Improve Orthotic Treatment

    SBC: Innovative Design Labs Inc.            Topic: NICHD

    DESCRIPTION provided by applicant Project Summary Abstract Walking one of the most important functional activities in humans is a hallmark of independence an indirect indicator of overall functional ability and a valuable fitness activity helpful in controlling obesity Cerebra Palsy CP is the most common disabling in children and almost all of these children have gait that is impaired in ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health

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