Award Data

PROJECT SUMMARY Cardiac valve repair or replacement is indicated when progression of degenerative disease or bacterial infection of the native valve results in valvular dysfunction, thereby impacting cardiac output. Both procedures require the use of a woven or knitted polyester material with an internal reinforcement (Teflon, silicone or metal) to either stabilize the native valve (annuloplasty r ...

7. Project Summary/Abstract We propose to develop a Biological Small-angle X-ray Scattering (BioSAXS) station for the Compact Light Source, a powerful new generation of X-ray sources, which will enable biologists and biochemists to pursue state-of-the-artresearch in macromolecular structure studies in their own laboratories. The frontier of structural biology is the determination of large macromol ...

ABSTRACT: Current composite USAF platforms suffer damage during media blast stripping operations. This is a pervasive issue, with repair being laborious and costly, a material solution is needed to fill in existing damages to the composite skin and provide a protective barrier against future aggregate blasting. NanoSperse proposes to develop a spray-on, flexible, highly erosion resistant polymer ...

DESCRIPTION (provided by applicant): Sustained-release narcotic drugs are highly sought after by drug abusers because they provide a much more powerful euphoric high than immediate-release formulations. Drug abusers easily defeat the sustained-release feature then ingest, snort or inject the narcotic drug for an immediate and potent drug high. The abuse of oxycodone (Purdue Pharma's "OxyContin(tm) ...

DESCRIPTION provided by applicant The growing populations of the elderly and those with type II diabetes are at high risk for developing chronic wounds that are slow to heal Effective therapeutics to promote wound healing could significantly improve the lives of these people Normal wound healing involves a coordinated cascade of events that are stimulated in part by the hypoxia that results f ...

DESCRIPTION (provided by applicant): Objective: This Phase 1 SBIR proposes to optimize the interface and interaction of a digital translation of Evidence Based Falls Prevention programs for use across the continuum of care and community living that affordseasy adoption, adherence and monitoring of falls prevention exercises for all stakeholders including those with limited technical experience. Pu ...

ABSTRACT: For certain weapons systems, lethality is directly correlated to the orientation of the weapon with respect to the target at impact, also known as the angle of incidence (AOI). Accurately measuring AOI is of the utmost importance in developing and advancing state-of-the-art precision weapon systems. Currently, there is no commercially available sensor system for measuring AOI to the pre ...

Current nondestructive methods for assessing structural damage and cracks/delaminations on aircraft are cumbersome, and require rigorous time-consuming testing. To overcome the limitations of conventional nondestructive inspection/evaluation, Intelligent Optical Systems (IOS), in collaboration with Professor Ajit Mal of the Department of Mechanical and Aerospace Engineering at the UCLA School of E ...

The development of a miniature, very-low power, rubidium clock specifically designed for integration into an airborne GPS receiver is described. The primary Phase I objective is to demonstrate the capability of an integrated Low-Power Precision Time Source (LPPTS) to minimize the Time-to-First Fix in a jamming environment. To accomplish this objective, Kernco proposes to fabricate, test and deli ...

DESCRIPTION (provided by applicant): An estimated 5.4 million Americans had Alzheimer's disease in 2012 and a 50% increase in this number is expected by 2030. The majority of these patients (70%) will live at home where they receive 75% of their care frominformal caregivers, unpaid individuals such as family members, friends, and neighbors. These caregivers provide valuable services, often a ...