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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Coils for Human Whole Body Imaging at 7T

    SBC: LIFE SERVICES L.L.C.            Topic: NIBIB

    DESCRIPTION provided by applicant For this Phase II STTR proposal the investigators plan to develop and commercialize the radiofrequency RF coil technology to make T body MRI possible and to translate this new technology to vastly improve T clinical MRI as well In the Phase I project leading to this proposal all specific aims were accomplished to demonstrate the feasibility of safely an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. A Novel Vaccine to Prevent Urinary Tract Infections

    SBC: SYNTIRON, LLC            Topic: NIAID

    DESCRIPTION provided by applicant Urinary tract infections UTIs caused by extraintestinal pathogenic E coli ExPEC account for nearly million emergency room visits and hospitalizations per year for women in the U S alone Approximately half of all women will experience a symptomatic UTI in their lifetime and will experience a recurrence within to months While several ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Immuno-Chemotherapy to Shorten TB Treatment

    SBC: PAI Life Sciences, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Tuberculosis TB a disease caused by Mycobacterium tuberculosis Mtb is an ongoing threat to public health Globally approximately two billion people are infected with TB with nine million newly diagnosed cases of active TB each year causing million deaths Furthermore mismanagement or inappropriate treatments for TB infections can result in the deve ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Direct visualization assay for detection of B. burgdorferi in early Lyme Disease

    SBC: Rarecyte, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Lyme disease a tick borne infection caused by the spirochete Borrelia burgdorferi has expanded to an estimated US cases per year Currently approved tests of immune response are sub optimal and often give negative results early in the disease The research outlined in this application is to develop a diagnostic blood test that directly visualizes B b ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Therapy and Prophylaxis for Genital Tract Infection

    SBC: THERAPYX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Genital tract infection with Neisseria gonorrhoeae gonorrhea does not induce a state of specific protective immunity and can be acquired repeatedly Despite public health measures the disease persists at an unacceptably high frequency there is no vaccine against it and resistance even to the latest generations of antibiotics continues to emerge Recent fin ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Refinement of an autodissemination station for control of mosquito vectors

    SBC: Springstar, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant The urban container breeding mosquitoes Aedes albopictus and Aedes aegypti are vectors for deadly and debilitating diseases such as dengue and Chikungunya There is no known vaccine or treatment for either disease mosquito control is the only effective means of preventing and managing outbreaks But container species are difficult to manage using conventional ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Subcutaneous Drug Development for Portal Hypertension Ascites

    SBC: PharmaIN Corporation            Topic: 300

    DESCRIPTION provided by applicant The prevalence of all types of ascites irrespective of the cause is in with of these due to cirrhosis Ascites is treated with a salt restricted diet and pharmacologic therapy using diuretics However in to of patients with ascites the ascites becomes refractory to medical therapy Half of patients who develop refractory ascites due ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Medical countermeasure after radiation exposure

    SBC: PharmaIN Corporation            Topic: NIAID

    DESCRIPTION provided by applicant New treatments for radiation injury to the GI tract are desperately needed to ensure survival after exposure to ionizing radiation arising from accident nuclear warfare or terrorist attacks dirty bombs Radiation injuries to the hematopoietic system and the GI tract are fatal with the latter more acutely fatal No treatment is available fo the more acute l ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Reproducibility Assessment for Multivariate Assays

    SBC: INSILICOS            Topic: 400

    DESCRIPTION provided by applicant This Small Business Innovation Research project addresses the problem of assessing reproducibility in analyzing high throughput data In feature selection for data with large numbers of features it is well known that some features will appear to affect an outcome by chance and that subsequent predictions based on these features may not be as successful as ini ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Pediatric Anxiety Intervention with an Entertaining Video Game

    SBC: ADVANCED MEDICAL ELECTRONICS CORPORATION            Topic: 104

    DESCRIPTION provided by applicant This project will develop an immersive video game for children with social anxiety disorder SAD The video game will serve as a vehicle to deliver evidence based Cognitive Behavioral Therapy CBT in an engaging manner so that its target audience perceives it as entertainment rather than therapy Social interactions are crucial to success in all areas of life ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health

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