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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. A screening assay for chemicals that affect the differentiation of human neural cells.

    SBC: Nzumbe, Inc.            Topic: NIEHS

    DESCRIPTION provided by applicant Human brain development represents a highly vulnerable time to chemical exposures because immature cells are actively undergoing differentiation into more complex cell types e g neurons astrocytes oligodendroglia to form neural circuits A major reason for this vulnerability is that neuronal differentiation requires critical time dependent changes to the ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Identifying activators of interferon regulatory factors for neuroprotection

    SBC: Neuralexo, LLC            Topic: NINDS

    DESCRIPTION provided by applicant Stroke is a leading cause of morbidity and mortality in the United States However less than of patients are eligible for the current approved interventions of tissue plasminogen activator or thrombectomy We seek to develop new therapeutics to reduce the extent of damage and functional impairment resulting from ischemic injury to the brain an area of signi ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Custom Fit 3D-Printed Pediatric Respiratory Masks

    SBC: ADVANCED MEDICAL ELECTRONICS CORPORATION            Topic: NICHD

    DESCRIPTION provided by applicant This project will develop an FDA approved process D printing system and advanced D printable material suitable for point of care manufacturing of custom fit continuous positive airway pressure CPAP masks for neonates In extremely low birth weight infants nasal CPAP therapy is delivered via soft biocompatible neonatal sized nasal masks suitable for lon ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Distance Filtering System for Retinal Implants

    SBC: ADVANCED MEDICAL ELECTRONICS CORPORATION            Topic: N

    DESCRIPTION provided by applicant We propose to develop and evaluate the utility of a novel input camera system for retinal prosthetics that allows users to filter optical imagery based on distance from the observer We call this andquot depth filteringandquot which can be accomplished with a depth sensing stereoscopic camera system Retinal prostheses can restore partial vision to people bli ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Access to Exercise Stress Testing for Elderly Native Americans in Remote Locations

    SBC: ADVANCED MEDICAL ELECTRONICS CORPORATION            Topic: N

    DESCRIPTION provided by applicant Heart disease is the leading cause of death among elderly American Indians and Alaska Natives Heart disease death rates for elderly American Indians at per are percent higher than average in the total U S population Most elderly Native Americans live in remote locations and lack transportation to healthcare facilities This is a key barrie ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Modeling of Integrally Bladed Rotor (IBR) Blends

    SBC: Optimal Solutions Software, LLC            Topic: N13AT002

    The main goal of Phase II is to validate the Phase I prototype and develop an integrated design and analysis tool for assessing large damage and blends for compressor IBRs on gas turbine engines and other blade systems. This tool will have at its core the automated analytical modeling of as-measured or as-expected airfoil blends for the structural and aero response to the shape change due to blend ...

    STTR Phase II 2015 Department of DefenseNavy
  7. Design, Reconfigure, and Evaluate Autonomous Models in Training

    SBC: Tier 1 Performance Solutions, LLC            Topic: AF15AT14

    ABSTRACT: The proliferation of autonomous- and human-machine systems necessitates the creation of new tools for system design and evaluation. Key among these are simulation testbeds that support interactions between multiple warfighters and systems, and methods for creating and integrating intelligent agent models into simulation environments. We see a significant opportunity to advance the state ...

    STTR Phase I 2015 Department of DefenseAir Force
  8. Development of novel compounds for the treatment of atrial fibrillation

    SBC: Elex Biotech, Inc            Topic: NHLBI

    DESCRIPTION provided by applicant Atrial fibrillation AF is the most prevalent type of cardiac arrhythmia in the developed world affecting million people in the United States alone a number that is expected to double by because of population aging Current pharmacological options are ineffective which may be in part because these drugs fail to target key pathogenic mechanisms Recen ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. StrikeVEMP: Automated Portable Bone-Conducted Force Stimuli for Recording Acceleration-Produced coVEMPs

    SBC: Ear And Skull Base Center, Inc.            Topic: NIDCD

    DESCRIPTION provided by applicant Each year million Americans go to health care providers because of vertigo dizziness or balance problems It is the second most common complaint heard in doctorandapos s offices and will occur in of the nationandapos s population at sometime in their lives From through of US adults aged years and older million Americans had ve ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Reverberation Mitigation of Speech

    SBC: Minerva Systems & Technologies, LLC            Topic: AF15AT17

    ABSTRACT: Speech recognition technology is in wide use today and has been successfully integrated in a number of applications. Most of these applications require a microphone located near the talker. However, when a distant microphone is used where the speaker is at some distance from the microphone as in a hands-free communication, or in a meeting room, there is a major problem with the captured ...

    STTR Phase I 2015 Department of DefenseAir Force
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