Award Data

DESCRIPTION (provided by applicant): This project will develop a digital wireless transceiver integrated circuit (IC) and antenna for a companion microphone system that can be packaged in an in-the-ear (ITE) hearing aid. The use of companion microphones has been shown to improve perception of a companion's speech in noise filled environments such as restaurants, entertainment events, and urban are ...

DESCRIPTION (provided by applicant): In this phase I STTR, Advanced Medical Electronics Corp. and the JHU Lions Vision Center are teaming up to create a hardware toolkit that will allow personal computers to be used as accurately calibrated and controlled vision test instruments. This toolkit is predicated on the fact that modern PCs and displays (either CRT-based or flat screen) have sufficient c ...

DESCRIPTION (provided by applicant): This proposed project seeks to prove the feasibility of an ultra-low power, digital wireless transceiver integrate circuit (1C) which would enable communication between two hearing aids. Wireless synchronization between the digital signal processors of two hearing instruments is a new technology for next generation hearing instruments. Approximately 70% of fitt ...

DESCRIPTION (provided by applicant): Glioblastoma Multiforme (GBM) is a lethal brain tumor that typically causes death within two years after initial diagnosis. GBM accounts for 25% of all primary brain tumors in adults. Despite improvements in precise surgical de-bulking, radiation, and drug therapy, the prognosis for GBM patients has not significantly changed in decades. Novel therapies are ther ...

DESCRIPTION (provided by applicant): Alcohol abuse, dependence, and related societal effects exert a tremendous toll on world-wide and American health and economics. Given this devastating impact, the significant lack of pharmaceutical intervention, even for those patients seeking treatment, is troubling. This phase 1 Small Business Technology Transfer Research (STTR) project will apply novel nasa ...

The US Navy is interested in analytical methods and tools to predict ship bubbly wake acoustic signatures for waterjet propelled surface ships with underwater waterjet outlet such as the Littoral Combat Ship (LCS). Wake features of propeller-driven ships are well studied, but the ability to perform predictive analysis and wakes from waterjet driven advanced hull forms do not currently exist. The m ...

DESCRIPTION (provided by applicant): The NIH has expressed a need for focused development of PET and SPECT brain ligands as well as research and development of new technologies for radiotracer production to aid in animal and human drug research. PET compounds are powerful imaging tools, but are often difficult and slow to produce. By applying high speed microfluidic techniques, multiple PET brain ...

DESCRIPTION (provided by applicant): Plants produce many types of molecules, such as chalcones flavones and flavonones, that interact with human estrogen receptors (ERs). Some of these may have therapeutic value in different types of hormone-sensitive cancer, but the full capacity of the plant genome to generate such ligands has not been explored. This project uses a functional genomics approach i ...

DESCRIPTION (provided by applicant): While there exist numerous artificial sweeteners that are commercially available, designed to provide zero- or low-calorie artificial alternatives to sucrose/high fructose corn syrup, there remain concerns regarding potential health concerns in the general population or unique subsets of individuals (e.g. phenylketonurics and diabetics). Moreover, altered sugar ...

DESCRIPTION (provided by applicant): The purpose of this project is to develop a nanoparticle-based drug delivery system for use in the treatment of the exudative form of aged-related macular degeneration (ARMD). ARMD is the leading cause of blindness for individuals over fifty-five years of age that live in the industrialized world. It affects approximately 10 million people in the US and as many ...