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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Optimized lactoferrin for treatment of intracerebral hemorrhage

    SBC: Pharmareview Corporation            Topic: NINDS

    DESCRIPTION provided by applicant Intracerebral hemorrhage ICH is a major public health problem with highest mortality rate of all stroke subtypes and long term disability Since there are no available FDA approved therapies for ICH it is of enormous importance to establish effective treatment for this medical condition Following ICH the deposited blood is damaging initially via compression ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Using game mechanics to improve outcomes among stem cell transplant survivors

    SBC: Radiant Creative Group, LLC            Topic: NCI

    DESCRIPTION provided by applicant Adolescent and young adult AYA hematopoietic stem cell transplantation HSCT patients face a variety of well documented physical and emotional challenges In addition to undergoing a life threatening procedure that involves an intense treatment regimen and lengthy hospital stay these patients face a protracted month recovery period marked by numerous phy ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Triple Re-uptake Inhibitor, SKL 10406, as a New Treatment for Alcohol Dependence

    SBC: Medication Discovery Texas, Inc            Topic: NIAAA

    DESCRIPTION provided by applicant Three medications are approved by the FDA as treatments for alcohol dependence disulfiram acamprosate and naltrexone but these are seldom prescribed due to poor efficacy or side effects Another topiramate is effective for reducing alcohol use but it causes a range of side effects that limit its tolerability Another clas of potentially effective treatment ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Custom Fit 3D-Printed Pediatric Respiratory Masks

    SBC: ADVANCED MEDICAL ELECTRONICS CORP            Topic: NICHD

    DESCRIPTION provided by applicant This project will develop an FDA approved process D printing system and advanced D printable material suitable for point of care manufacturing of custom fit continuous positive airway pressure CPAP masks for neonates In extremely low birth weight infants nasal CPAP therapy is delivered via soft biocompatible neonatal sized nasal masks suitable for lon ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. APPSPIRE: expanding the reach of an innovative tobacco control program for youth

    SBC: Radiant Creative Group, LLC            Topic: NIDA

    DESCRIPTIONprovided by applicantMobile phone technology offers a variety of opportunities for innovative approaches to health communication and interventionThese opportunities have been amplified by the emergence of next generation smartphone devices that are capable of rich multimedia and sophisticated interactivitySmartphone based programs can be integrated seamlessly into a userandapos s daily ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Live-Cell Fluorescence Lifetime FRET Assays for HTS

    SBC: Fluorescence Innovations, Inc.            Topic: R42

    DESCRIPTION provided by applicant We seek to develop and commercialize a powerful technology platform to increase dramatically the effectiveness of drug discovery using high throughput screening HTS based on fluorescence lifetime FLT readouts of FRET in live cells This breakthrough is enabled by a combination of two complementary and synergistic technologies fluorescent biosensor engineer ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Small Molecules To Inhibit PCSK9-LDLR

    SBC: Small Molecule PPI Mimics LLC            Topic: NHLBI

    DESCRIPTION provided by applicant This proposal is to prepare small molecules that will inhibit the protein protein interaction between a protein called PCSK and the LDLR receptor This is an extremely well validated target for reduction of andquot badandquot cholesterol LDL and therefore controlling coronary artery disease Orally available small molecules are the preferred therapeutic mo ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Distance Filtering System for Retinal Implants

    SBC: ADVANCED MEDICAL ELECTRONICS CORP            Topic: N

    DESCRIPTION provided by applicant We propose to develop and evaluate the utility of a novel input camera system for retinal prosthetics that allows users to filter optical imagery based on distance from the observer We call this andquot depth filteringandquot which can be accomplished with a depth sensing stereoscopic camera system Retinal prostheses can restore partial vision to people bli ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Access to Exercise Stress Testing for Elderly Native Americans in Remote Locations

    SBC: ADVANCED MEDICAL ELECTRONICS CORP            Topic: N

    DESCRIPTION provided by applicant Heart disease is the leading cause of death among elderly American Indians and Alaska Natives Heart disease death rates for elderly American Indians at per are percent higher than average in the total U S population Most elderly Native Americans live in remote locations and lack transportation to healthcare facilities This is a key barrie ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Modeling of Integrally Bladed Rotor (IBR) Blends

    SBC: Optimal Solutions Software, LLC            Topic: N13AT002

    The main goal of Phase II is to validate the Phase I prototype and develop an integrated design and analysis tool for assessing large damage and blends for compressor IBRs on gas turbine engines and other blade systems. This tool will have at its core the automated analytical modeling of as-measured or as-expected airfoil blends for the structural and aero response to the shape change due to blend ...

    STTR Phase II 2015 Department of DefenseNavy
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