Award Data

DESCRIPTION provided by applicant For this Phase II STTR proposal the investigators plan to develop and commercialize the radiofrequency RF coil technology to make T body MRI possible and to translate this new technology to vastly improve T clinical MRI as well In the Phase I project leading to this proposal all specific aims were accomplished to demonstrate the feasibility of safely an ...

The technical objective of this proposal is to demonstrate a Quantum Cascade Laser (QCL) emitting in the 3.0-3.5 & #181;m wavelength region, which employs a metamorphic buffer layer (MBL). It is the goal of this program to develop a QCL single-stripe device which will operate in a single, diffraction-limited lobe under room temperature continuous-wave (CW) operation to moderately high (~ 0.5 W) ou ...

ABSTRACT: ORBITEC will develop a new diagnostic to acquire simultaneous planes of velocity and temperature data at very high repetition rates. This diagnostic relies on a novel pulse burst laser system, a phosphor thermometry technique, and the mature PIV method. The work plan will involve developing and testing the laser, refining the integrated technique, and demonstrating it in a supersonic ...

The use of Net-Centric Enterprise Services (NCES) to provide ubiquitous access to information within the Department of Defense presents challenges in both the design and implementation of these systems. The need to provide information to the war-fighter in a timely manner while maintaining the security of the system in challenging environments far exceeds the capabilities of present day enterpris ...

DESCRIPTION (provided by applicant): Over 5 million word recognition tests are administered annually by audiologists in the United States with an associated cost of more than $100 million. These tests are currently performed manually by highly trained audiologists. This application describes the Phase II development of automated clinical speech recognition tests using clinical test recordings and ...

DESCRIPTION (provided by applicant): The principle of ALARA (as low as reasonably achievable) has been developed to reduce the risk of induced malignancy from radiation exposure, In practice this requires a rigorous quality control process for clinical operations in radiology. Currently, a critical tool (a radiographic test phantom) needed for quality control is not commercially available for c ...

DESCRIPTION (provided by applicant): Reading the conformational state of membrane proteins is central to understanding their role ir cell signaling, to using them as sensor elements and for screening candidate drug compounds that are targeted toward this important class of biomolecules. While the patch clamp technique for doing this is ubiquitous, it does have significant limitations: two electrod ...

DESCRIPTION (provided by applicant): According to the National Survey of Drug Use and Health (NSDUH) of 2008, 7.2 million Americans are in need of treatment for Substance-Related Disorders (SRDs), and a large proportion of those need treatment for opiate pain reliever, heroin, and alcohol addiction. Naltrexone (NTX), an opioid antagonist, is currently used in oral tablet form to help maintain opio ...