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ABSTRACT Leptomeningeal Metastases LM is a condition in which tumor cells from a primary tumor metastasize invade the subarachnoid space SAS and spread throughout the cerebrospinal fluid CSF resulting in seeding along the meninges brain and spinal cord LM represents a devastating event of cancer progression There are cases annually and currently no cure with average survival of months with current ...

ABSTRACT When Cryptococcus is manifested as cryptococcal meningitisCMit creates a large burden of mortality and morbidity to the patient and is very difficult for the clinician to treatThere are now an estimatedUS cases andcases of CM worldwide annuallywith estimated mortality ofper yearCM is caused when Cryptococcus neoformansa basidiomycete fungal pathogeninvades the central nervous systemCNSIt ...

To address the needs of Navy to successfully produce 7000 series aluminum alloy components, Sentient proposes to develop a hybrid additive manufacturing (AM) process for this topic. Hybrid AM use a secondary process (e.g. peening, burnishing) along with primary AM process to tightly control thermal profile and stress evolution locally and globally, resulting enhanced part quality (e.g. negligible ...

GaN power semiconductors offer a technological breakthrough for improving the performance of power electronics including power density, conversion efficiency, and reliability of power converters. These are the three most critical requirements for military, aerospace and many commercial applications. In this STTR program, Qrona Technologies will collaborate with the University of Central Florida to ...

PROJECT SUMMARYAdolescent obesity is a multifaceted public health concernparticularly for Black and Hispanic adolescents who are disproportionately impacted by this epidemicResearch suggests that exposure toand consumption offoods prepared outside of the home contribute to having a high body mass indexBMIOn averageyouth consume over one third of their daily calories from meals prepared away from h ...

Earths outer radiation belt, which consists of electrons with hundreds of keV to MeV energies, is a highly dynamic and driven environment.The large variations in electron flux, if unaccounted for, can cause satellites that travel through this complex region to experience anomalous behavior ranging from temporary satellite outages due to electrostatic discharge events in system electronics to poten ...

x-Ga2O3 has emerged as a potentially disruptive semiconductor with a predicted breakdown field of ~8 MV/cm which is more than twice the breakdown field for the incumbent wide bandgap semiconductors GaN and SiC. The availability of -Ga2O3 bulk substrates sets this material apart from other wide bandgap materials for power electronic applications. However, the challenge is to find suitable epitaxial ...

SIFT proposes Network Enforcement Using TRansactONs (NEUTRON) a dynamic fine-grained network enforcement policy design that captures network dependencies.NEUTRON closes the knowledge gap between mission needs and observed network traffic to increase mission network awareness. Then using that knowledge develops a revolutionary security enforcement policy based on network transactions.It reduces the ...

DESCRIPTION provided by applicant For this Phase II STTR proposal the investigators plan to develop and commercialize the radiofrequency RF coil technology to make T body MRI possible and to translate this new technology to vastly improve T clinical MRI as well In the Phase I project leading to this proposal all specific aims were accomplished to demonstrate the feasibility of safely an ...

To address the Navy"s need for a common, scalable, platform for multi-modal 1pA level current sensing for Electrocardiogram (ECG), Electroencephalogram (EEG), and Electrodermal Response (EDR) to be fielded as a miniature wearable device with non-contact electrodes, Sentient and the State University of New York (SUNY) propose to develop the Bioelectronic Fusion Sensor System (BioFuSenS) that will a ...