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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Small Molecule Inhibitor Therapeutic Target for Alzheimer's Disease.

    SBC: abSynapTex, LLC            Topic: NIA

    Project SummaryThe objective of our proposed research is to develop a water soluble molecule that can reduce the levels of amyloid betaAand Drpand prevent abnormal interactions between Aand Drpin Alzheimers diseaseADaffected neuronsOur previous AD studies foundincreased production and accumulation of Aand increased expression of Drpandan abnormal interaction between Aand Drpin AD neurons that was ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Developing an automated yeast dissection system for aging research

    SBC: Innovative BioChips LLC            Topic: NIA

    PROJECT SUMMARY Developing an Automated Yeast Dissection System for Aging ResearchAging is the single greatest risk factor for diseases that are principal causes of mortalityThe objectives of aging research are to discover key genes and pathways related to aging that may eventually contribute to retardation of aging and a delay in the onset of age associated diseasesThe budding yeast Saccharomyces ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Dose-ranging safety and efficacy studies to advance novel mechanism-of-action drug candidates to reverse age-related muscle degeneration

    SBC: RIDGELINE THERAPEUTICS LLC            Topic: NIA

    In the USthe number of individuals agedand older will increase byover the next decadeConcurrentlyMedicare costs are expected to double to treat chronic diseases that will plague this increasing number of older adultsOne of the most wide spread chronic diseases that affects older adults is sarcopeniawhich is observed inof adults overyears of age andof adults overyears of ageThis disease is characte ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a novel Balloon Occlusion Sheath for Stroke (BOSS)

    SBC: Marblehead Medical LLC            Topic: 106

    PROJECT SUMMARY ABSTRACTThis research program s broadlong term objective is to improve health outcomes for patients suffering fromacute ischemic strokeAISresulting from large vessel occlusionsWe will achieve this purpose by developingimproved access tools for stroke intervention procedureswhich specifically target tool innovations that providesupport for embolectomy devices and arrest flow during ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Modern Manufacturing for Liquid Rocket Engine Components

    SBC: ADVANCED POWDER SOLUTIONS INC            Topic: AF18AT009

    Liquid Rocket Engine (LRE) component manufacturing process by conventional processes are comprised of multi steps, components are fabricated by conventional machining from a forged or rolled billet/sheet. As a result a long lead time is needed and part acquisition time is high. So a low cost fabrication process is needed to replace current traditional processes. Low cost, rapid fabrication of this ...

    STTR Phase I 2018 Department of DefenseAir Force
  6. Midwave Infared (MWIR) Quantum Cascade Lasers (QCL) Thermal Monitoring

    SBC: MAX-IR LABS INCORPORATED            Topic: AF17AT026

    Max-IR Labs LLC, in collaboration with UT Dallas, successfully demonstrated construction and operation of a prototype Infrared Near-Field Scanning Optical Microscopy (IR-SNOM) instrument for high-spatial-resolution thermal mapping of small heat sources, in particular Quantum Cascade Laser (QCL) facets, during Phase I.Preliminary data demonstrated feasibility of implementation of this instrument an ...

    STTR Phase II 2018 Department of DefenseAir Force
  7. Enhancement of the Beneficial Effects of Mesenchymal Stem Cell (MSC) Treatment by the Caveolin-1 Scaffolding Domain Peptide (CSD)

    SBC: LUNG THERAPEUTICS INC            Topic: NHLBI

    Abstract Systemic sclerosissclerodermaSScis a chronic connective tissue disease in which lung fibrosis is the most frequent cause of deathSSc and idiopathic pulmonary fibrosis are the two most common disease that falls under the interstitial lung diseasesILDa grouping of devastating diseases in which lung fibrosis leads to progressive shortness of breatha very poor quality of lifeand death within ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Development of Tetracycline Analogs for Alcohol Use Disorder Treatment

    SBC: South Plains Biotechnology, Inc            Topic: 350

    Project Summary Abstract Statement of the problemOnly three pharmacotherapeutic treatments for Alcohol Use DisorderAUDare FDA approved and none are widely usedandltof AUD patientsor show a strong effect to reduce riskyor dependence based drinking in the long termandltsee sustained decreased drinking outcomesUnfortunatelyapproximatelyof the population suffers from AUD and overof all medical morbidi ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Development and Production of Standardized Reference Diets for Zebrafish Research

    SBC: Meridian Biotech, LLC            Topic: 101

    The over arching goal of this Phase I SBIR proposal is to begin to optimize and implement standard reference diets for the ZebrafishDanio rerioan animal model of critical importance to the understanding of human health and development of vertebrate organismsA key problem in the industry is that standardized diets or feed management strategies have not been developed for Danio rerioThese diets are ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Robot-Assisted Cognitive Training for Socially Isolated Older Adults with Mild Cognitive Impairment

    SBC: Applied Universal Dynamics, Corp.            Topic: NIA

    Project Summary Abstract This project will develop a Socially Assistive RobotSARto provide cognitive trainingin the form of learning to play the pianoto improve cognitive functioning and reduce feelings of loneliness in socially isolated older adultsThe SAR will administer cognitive training via guided practice on a set of standard piano lesson tasks designed to reflect particular cognitive functi ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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