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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Physics-Based Identification, Modeling and Management Infrastructure of Aeroelastic Limit-Cycle Oscillations

    SBC: Advanced Dynamics, Inc.            Topic: AF07T006

    The proposed research program aims to develop a physics-based identification, modeling and management infrastructure for aeroelastic limit-cycle oscillations. This infrastructure will be built upon high fidelity state-of-the-art theoretical/computational methods as validated and verified by available experimental data bases, and will include (1) rapid flutter boundary determination for a wide ran ...

    STTR Phase I 2007 Department of DefenseAir Force
  2. Transdermal Cannabidiol Delivery for Alcohol-Induced Neurodegeneration

    SBC: ALLTRANZ, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Treatment of alcohol use disorders (AUDs), commonly referred to as alcoholism, has been hampered by alcohol's promiscuous pharmacological effects and the complex etiology of addiction. People drink in excess for a variety of reasons, and an approach that targets more of these reasons will have greater commercial success than an approach that only targets a sole ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  3. ApoVax-SVN as a Novel Vaccine for Cancer Immunotherapy

    SBC: APOIMMUNE, INC            Topic: N/A

    DESCRIPTION (provided by applicant): The main objective of this proposal is to develop a novel cancer vaccine, ApoVax-SVN(tm) based on the use of a proprietary costimulatory chimeric ligand, 4-1BBL, designed to specifically deliver survivin, a tumor associated antigen (TAA) to professional antigen-presenting cells (APCs) and activate them for the generation of an effective anti-tumor immune respon ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  4. Development of Improved Earphone for Hearing Testing

    SBC: AUDIOLOGY, INC            Topic: N/A

    DESCRIPTION (provided by applicant): This project seeks to develop an earphone for diagnostic audiometry with features that will significantly increase the efficiency and decrease the cost of routine hearing testing. The most-often used earphones employ a supra-aural design that has several undesirable characteristics, including 1) an "occlusion effect", an artificial increase in sensitivity to bo ...

    STTR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  5. Targeted Transposons for Gene Therapy

    SBC: DISCOVERY GENOMICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Discovery Genomics, Inc. is focused on development of the Sleeping Beauty (SB) transposon system as a non-viral means of integrating new gene sequences in cells and tissues for therapeutic purposes. Here we propose to develop a method for improved targeting of the SB system to specific cell types following systemic injection by coupling a targeting tether to th ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  6. Transgenic plant cells as a source of hepatoprotective drugs

    SBC: NAPROGENIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Alcoholic liver damage (ALD) is among the top ten causes of death in the USA, but existing therapeutic interventions are relatively ineffective. Hepatocytes are susceptible to damage probably because they have a high level of alcohol dehydrogenase (ADH) which metabolizes alcohol to form acetaldehyde and reactive oxygen species (ROS), which are both cytotoxic. C ...

    STTR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  7. Hypericum extracts as potential anti-relapse medications in alcoholism

    SBC: NAPROGENIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Alcoholism is a complex disease and anti-relapse treatments should recognize this. For example, depression is a frequent precipitant of relapse (1) and is the most common co-morbid psychiatric disorder in alcoholism. An anti-relapse agent with antidepressant properties might therefore be valuable, specifically for this large subpopulation. In this regard, the ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  8. Novel Materials for Ultra-Sensitive Low-Frequency Magnetometers

    SBC: NVE CORP. (FORMERLY NONVOLATILE ELECTRONICS, INC.            Topic: N05T025

    In diverse application areas there is a need to develop magnetic field sensors which resolve small (nanoTesla-level) field perturbations at low (Hertz and milliHertz) frequencies. The emerging technology of spin-dependent tunneling is promising in that its attributes include low power, small size, low cost, IC compatibility (uses standard silicon microelectronics processing), and broad-band frequ ...

    STTR Phase II 2007 Department of DefenseNavy
  9. Enhancement of the baculovirus expression vector system

    SBC: PARATECHS CORP            Topic: N/A

    DESCRIPTION (provided by applicant): The baculovirus expression vector system (BEVS) is one of the most powerful and versatile eukaryotic expression systems. The BEVS is being used to produce antigens for vaccine development, to manufacture human therapeutics, to develop faster acting biological insecticides, and as a protein expression system for a multitude of research projects. However, a limit ...

    STTR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  10. Development of a Diagnostic Test for Alzheimer's Disease

    SBC: SCOUT DIAGNOSTICS            Topic: N/A

    DESCRIPTION (provided by applicant): The major barriers to preventing or treating Alzheimer's disease (AD) are its unknown pathogenesis/etiology and the lack of an objective, sensitive and specific biomarker of the disease, particularly at the early stages when therapeutic interventions would likely have the greatest efficacy. The basic hypothesis of this proposal is that levels of a novel protein ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
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