Award Data

DESCRIPTION (provided by applicant): Reliable diagnostic differentiation between acute and chronic myocardial infarcts would be of great benefit for cardiac surgeons and interventional cardiologists. Such differentiation could be used to make decisions about which vessels and in what order would be reopened or bypassed. MRI is an intrinsically noninvasive diagnostic tool and the Delayed Enhancemen ...

Effective task management is a critical component of mission success. As warfighters are given more information to monitor, however, their ability to detect and attend to critical information and tasks is stressed. An automatic task manager is needed to help ensure that responses to events occur in a timely manner. The foundation of such a tool is an accurate model of human dynamic attention. Many ...

DESCRIPTION provided by applicant Cancer is the second leading cause of death after heart disease in the US Chemotherapy is a mainstay of treatment after surgical removal of tumors but the balance of clinical benefit versus disabling or life threatening side effects is often uncertain Genotyping of cancers to identify mutated oncogenes has enabled an era of targeted therapy Drugs targeting ...

This Small Business Technology Transfer Phase II project will develop computational support tools for specifying, analyzing, and verifying designs for complex distributed systems, such as communication systems and transportation control systems. The tools will support a modeling language, called TIOA (Timed Input/Output Automata), developed before and during our Phase I project. The overall modeli ...

ABSTRACT: The overall goal of the proposed effort is to develop and demonstrate a general-purpose, fast, and reliable management and learning software tool for analyzing massive data sets generated by dynamic multi-disciplinary simulation. In Phase I, key technology elements were developed and proof-of-principle was successfully demonstrated. Data management software encapsulating salient feature ...

High current density carbon nanotube-based field emission arrays with uniform emission will be developed under this program. Working in conjunction with MIT, microfabrication techniques will be used to produce high density arrays of CNT emitters on substrates which incorporate feedback to ensure uniformity of emission between emitters. The feedback techniques employed will minimize thermal effec ...

The coupling of GPS and INS is often characterized as loose, tight, or ultra-tight depending on the nature of the GPS input to the navigation filter. Thus, considering the challenge of precision navigation without GPS, this project will test and validate the coupling of sensor (EO, IR) information such as ego-motion and position updates similar to the coupling of a GPS and INS system. This proje ...

DESCRIPTION (provided by applicant): Physical Sciences Inc. (PSI) and the Surgical Navigation and Robotics Laboratory (SNR) at Brigham and Women's Hospital (BWH) propose to develop and test a Smart Template to guide transperineal targeted prostate biopsiesand subsequent therapy under magnetic resonance imaging (MRI). The project aims to solve the problem of poor diagnostic yield in prostate b ...

DESCRIPTION (provided by applicant): This project proposes to build an integrated software-based system for enhancing the accuracy of tumor change detection. The intent of the system, called AutoRegister, which is to be deployed on a clinical magnetic resonance imaging (MRI) scanner platform, is to automate the alignment of a patient's brain scan with that of a prior scan, such that subseque ...

DESCRIPTION (provided by applicant): Approximately 80,000 Americans sustain acute tears of the anterior cruciate ligament (ACL) of the knee each year, with associated healthcare costs estimated at roughly 1 billion dollars annually. Surgical reconstruction followed by an extended rehabilitation period is commonly recommended for ACL tears. The purpose of this STTR project is to develop a comprehen ...