Award Data

DESCRIPTION (provided by applicant): The ability to culture human embryonic stem cells generated a great deal of excitement about their vast potential for treating a variety of human diseases such as diabetes, heart disease, neurological, retinal and skin disorders to name a few. Unlike adult stem cells, embryonic stem cells have indefinite growth potential and the potential to develop into any t ...

DESCRIPTION (provided by applicant): This project will develop a digital wireless transceiver integrated circuit (IC) and antenna for a companion microphone system that can be packaged in an in-the-ear (ITE) hearing aid. The use of companion microphones has been shown to improve perception of a companion's speech in noise filled environments such as restaurants, entertainment events, and urban are ...

DESCRIPTION (provided by applicant): In this phase I STTR, Advanced Medical Electronics Corp. and the JHU Lions Vision Center are teaming up to create a hardware toolkit that will allow personal computers to be used as accurately calibrated and controlled vision test instruments. This toolkit is predicated on the fact that modern PCs and displays (either CRT-based or flat screen) have sufficient c ...

DESCRIPTION (provided by applicant): This proposed project seeks to prove the feasibility of an ultra-low power, digital wireless transceiver integrate circuit (1C) which would enable communication between two hearing aids. Wireless synchronization between the digital signal processors of two hearing instruments is a new technology for next generation hearing instruments. Approximately 70% of fitt ...

DESCRIPTION (provided by applicant): Tumor markers, measured in peripheral blood, could assist in diagnosis and management of non-small cell lung cancer (NSCLC) and potentially improve historically dismal outcomes. Circulating antibodies, generated to a wide range of tumor-associated proteins, can be translated into a valuable blood test for lung cancer. Preliminary data supports this hypothesis. ...

Although carbon dioxide is monitored worldwide at hundreds of monitoring stations, existing monitoring methods, which rely on the use of high pressure calibration gas cylinders, are both labor intensive and expensive. Thus, there is a pressing need for an affordable, highly-accurate (1 part in 3000) carbon dioxide monitor for the ambient atmosphere. In addition to being extremely accurate, the r ...

National security interests related to the nonproliferation of weapons of mass destruction require the remote detection of trace gases associated with the nuclear fuel cycle. Newly developed, mid-infrared, quantum cascade lasers have the potential to contribute to this application. These small solid state lasers produce relatively high power in the infrared band of light where many gases can be ...

Based on in-depth experience with advanced optical ceramics, nano-particle coating, nanoceramic sintering and superplasticity deformation, in this program, Agiltron, Inc. and Florida International University propose to develop next generation airframe and engine materials made of CNT/alumina nano-composites. The proposed approach uniquely combines low-cost and potentially large scale technology of ...

We propose to develop new polymer-ceramic nanoparticle composites for high power capacitors. The new approach combines the leading-edge nanomaterials development and manufacturing at Agiltron will transfer the high dielectric constant fillers to our new nanodielctrics with extremely improved breakdown strength and extensively lowered dielectric loss. We expect to fully overcome the problems of cu ...

DESCRIPTION (provided by applicant): The trigger for autoimmune destruction of pancreatic beta cells in Type 1 diabetes (T1D) is unclear. Evidence exists for the role of increased intestinal permeability, secondary to intestinal tight junctions (tj) disassembly, in the pathogenesis of various autoimmune diseases including T1 D. Over the last decade our studies have focused on the mechanism(s) of a ...