Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Development of PAR2 Inhibitors for the Treatment of Nonalcoholic steatohepatitis

    SBC: OASIS PHARMACEUTICALS, LLC            Topic: NIDDK

    DESCRIPTION provided by applicant Non alcoholic steatohepatitis NASH is characterized by fatty changes in the liver with inflammation and hepatocellular injury that in advanced stages leads to fibrosis and cirrhosis and high mortality rates NASH is frequently associated with other common metabolic abnormalities such as insulin resistance and visceral obesity Liver transplantation is curren ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Brain penetrant Hsp90 inhibitors for Alzheimer's disease

    SBC: YUMA THERAPEUTICS CORPORAITON            Topic: NIA

    DESCRIPTION provided by applicant Neurodegeneration in Alzheimerandapos s disease AD may result from deposition of A as plaques in brain tissue However less effort has been made to elucidate the role of tau containing neurofibrillary tangles NFTs in AD Accumulating evidence suggests that tau containing NFTs is an important component in the initiation and progression of AD and other neu ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Extending Genome-Phenome Analysis

    SBC: SimulConsult, Inc.            Topic: 172

    DESCRIPTION provided by applicant The declining cost of whole exome sequencing WES is nearing the point at which the spread of WES into clinical practice will be limited largely by the cost of interpreting the results and comparing them to the patientandapos s clinical findings This project builds on our demonstrated capability to reduce this interpretation cost by pairing our diagnostic sof ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Emergency Operations Plans for Individuals with Disabilities

    SBC: Praxis            Topic: NICHD

    DESCRIPTION provided by applicant The proposed project is designed to fill an important yet unmet need by developing an online education program using simulations and scenario based learning to reach all public health and safety emergency responders and students responsible for emergency planning with and response for individuals with disabilities In Phase II the applicant organization P ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Optical Remote Detection of Low Level Earth Surface Vibrations

    SBC: Spectral Sciences, Inc.            Topic: AF12BT02

    ABSTRACT: Underground facilities can be used by rogue governments to conceal command-and-control and to manufacture weapons of mass destruction, and are an increasingly important operational challenge to U.S. military forces. Our objective is to determine improved methods of detection essential to address this critical intelligence need. Activity below the ground causes seismic surface waves th ...

    STTR Phase II 2014 Department of DefenseAir Force
  6. A FAP-Activated Proteasome Inhibitor for Killing Solid Tumors

    SBC: ARISAPH PHARMACEUTICALS, INC.            Topic: 102

    DESCRIPTION provided by applicant Cancer is the second leading cause of death after heart disease in the US Chemotherapy is a mainstay of treatment after surgical removal of tumors but the balance of clinical benefit versus disabling or life threatening side effects is often uncertain Genotyping of cancers to identify mutated oncogenes has enabled an era of targeted therapy Drugs targeting ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Development of a clinical hemoglobin modulator

    SBC: Phoenicia Biosciences, Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant The thalassemias and sickle cell disease are serious genetic blood diseases which are WHO designated as a growing global health burden The disorders decrease production or alter structure of the b chain of adult hemoglobin A and are characterized by anemia chronic organ damage and early mortality HbF is another type of normal hemoglobin which is suppres ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Coils for Human Whole Body Imaging at 7T

    SBC: LIFE SERVICES L.L.C.            Topic: NIBIB

    DESCRIPTION provided by applicant For this Phase II STTR proposal the investigators plan to develop and commercialize the radiofrequency RF coil technology to make T body MRI possible and to translate this new technology to vastly improve T clinical MRI as well In the Phase I project leading to this proposal all specific aims were accomplished to demonstrate the feasibility of safely an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Extended-Range Atmospheric Sensing Suite (ERASS) for Deep Turbulence Characterization

    SBC: MV Innovative Technologies LLC (DBA: Opt            Topic: AF11BT41

    ABSTRACT: During Phase 1 the technical feasibility of the Extended-Range Atmospheric Sensing Suite (ERASS) which includes a set of sensors at three different wavelengths (0.53, 1.06, and 1.55 microns), capable of operating in strong-scintillation conditions over long (>100 km) propagation paths and providing both near and far-field measurements of major atmospheric turbulence, laser beam and imag ...

    STTR Phase II 2014 Department of DefenseAir Force
  10. New learning technologies for exploitation of layered sensor data

    SBC: Longshortway Inc.            Topic: AF12BT14

    ABSTRACT: LongShortWay Inc, Boston University, and Applied Communication Sciences propose to develop a dynamic multi-sensor learning system that can adaptively detect target types and activities and schedule sensors to optimize the detection rate BENEFIT: Improved detection rate, increase field of view

    STTR Phase II 2014 Department of DefenseAir Force
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