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The combination of X-ray absorption spectroscopy (XAS) with x-ray emission spectroscopy (XES) provides unique diagnostic analysis of both the structure and chemical composition of complex heterogeneous materials. The penetration of X-rays make this method ideal for studying and optimizing material properties under realistic, real time reaction conditions with simultaneous analysis of r ...

NOVA Scientific proposes the development of efficient position sensitive detectors capable of time-tagging epithermal energy neutrons with high accuracy and efficiency. These devices will be able to perform energy-resolved imaging at the pulsed neutron sources and detect every neutron with spatial resolution of & lt; 60 m and timing resolution & lt; 1 s for thermal neutrons and & lt;100 ns for epi ...

ABSTRACT: Modern gas-turbine engines designs for the next-generation warfighter need to reduce exhaust gas temperatures to reduce effective thermal footprint thereby improving the mission capability. In such situations, high-altitude engine operation is often limited by the overall combustion efficiency, lean flame blow out (LBO) limit, and combustion instabilities that results in narrower opera ...

DESCRIPTION provided by applicant Cancer is the second leading cause of death after heart disease in the US Chemotherapy is a mainstay of treatment after surgical removal of tumors but the balance of clinical benefit versus disabling or life threatening side effects is often uncertain Genotyping of cancers to identify mutated oncogenes has enabled an era of targeted therapy Drugs targeting ...

MapReduce is a very popular data analytic framework that is widely used in both industry and scientific research. Despite the popularity of MapReduce, there are several obstacles to applying it for developing some commercial and scientific data analysis applications. The project will develop a Native data FOrmat MapREDuce-like framework, iNFORMER, based on OSUs SciMate architecture. The framework ...

ABSTRACT: Phosphor materials are currently being utilized in a wide variety of applications. The requirements for phosphors have become more and more stringent with smaller and smaller particles being required. In the Phase I program UES Inc. in collaboration with Penn State University has demonstrated the feasibility of a few approaches for high rate production of high efficiency IR to IR up-con ...

DESCRIPTION (provided by applicant): Physical Sciences Inc. (PSI) and the Surgical Navigation and Robotics Laboratory (SNR) at Brigham and Women's Hospital (BWH) propose to develop and test a Smart Template to guide transperineal targeted prostate biopsiesand subsequent therapy under magnetic resonance imaging (MRI). The project aims to solve the problem of poor diagnostic yield in prostate b ...

Adding thermal insulation to existing building envelopes can be an effective way of reducing building energy use. While most thermal insulation materials are affordable, the cost of installing thermal insulation into existing buildings can be expensive. Real facades are also characterized by many unique elements that affect their rated thermal performance, such as corners, windows, d ...

DESCRIPTION (provided by applicant): This project proposes to build an integrated software-based system for enhancing the accuracy of tumor change detection. The intent of the system, called AutoRegister, which is to be deployed on a clinical magnetic resonance imaging (MRI) scanner platform, is to automate the alignment of a patient's brain scan with that of a prior scan, such that subseque ...

DESCRIPTION provided by applicant Neurodegeneration in Alzheimerandapos s disease AD may result from deposition of A as plaques in brain tissue However less effort has been made to elucidate the role of tau containing neurofibrillary tangles NFTs in AD Accumulating evidence suggests that tau containing NFTs is an important component in the initiation and progression of AD and other neu ...