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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. 2-5A Antisense Targeting of Telomerase RNA

    SBC: RIDGEWAY BIOSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The ribonucleoprotein complex telomerase has been implicated in the establishment and progression of many different types of tumors. Telomerase activity is detected in roughly 80 percent of all tumor cell types, but is absent in most normal cells. Thus, the disruption of telomerase activity is a particularly attractive means for treating multiple types of cance ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  2. Advanced Compact X-Ray Spectrometer with High Resolution and Efficiency

    SBC: INCOM, INC.            Topic: 03a

    The combination of X-ray absorption spectroscopy (XAS) with x-ray emission spectroscopy (XES) provides unique diagnostic analysis of both the structure and chemical composition of complex heterogeneous materials. The penetration of X-rays make this method ideal for studying and optimizing material properties under realistic, real time reaction conditions with simultaneous analysis of r ...

    STTR Phase II 2014 Department of Energy
  3. Advanced Energy-Resolving Imaging Detectors for Applications at Pulsed Neutron Sources

    SBC: NOVA SCIENTIFIC INCORPORATED            Topic: 09a

    NOVA Scientific proposes the development of efficient position sensitive detectors capable of time-tagging epithermal energy neutrons with high accuracy and efficiency. These devices will be able to perform energy-resolved imaging at the pulsed neutron sources and detect every neutron with spatial resolution of & lt; 60 m and timing resolution & lt; 1 s for thermal neutrons and & lt;100 ns for epi ...

    STTR Phase II 2014 Department of Energy
  4. Advanced Optical Diagnostics/Modeling Platform for Plasma Assisted Combustion in Vitiated Air

    SBC: SPECTRAL ENERGIES LLC            Topic: AF13AT04

    ABSTRACT: Modern gas-turbine engines designs for the next-generation warfighter need to reduce exhaust gas temperatures to reduce effective thermal footprint thereby improving the mission capability. In such situations, high-altitude engine operation is often limited by the overall combustion efficiency, lean flame blow out (LBO) limit, and combustion instabilities that results in narrower opera ...

    STTR Phase I 2014 Department of DefenseAir Force
  5. A FAP-Activated Proteasome Inhibitor for Killing Solid Tumors

    SBC: ARISAPH PHARMACEUTICALS, INC.            Topic: 102

    DESCRIPTION provided by applicant Cancer is the second leading cause of death after heart disease in the US Chemotherapy is a mainstay of treatment after surgical removal of tumors but the balance of clinical benefit versus disabling or life threatening side effects is often uncertain Genotyping of cancers to identify mutated oncogenes has enabled an era of targeted therapy Drugs targeting ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. A MapReduce-like Data-Intensive Processing Framework for Native Data Storage and Formats

    SBC: RNET TECHNOLOGIES INC            Topic: 01c

    MapReduce is a very popular data analytic framework that is widely used in both industry and scientific research. Despite the popularity of MapReduce, there are several obstacles to applying it for developing some commercial and scientific data analysis applications. The project will develop a Native data FOrmat MapREDuce-like framework, iNFORMER, based on OSUs SciMate architecture. The framework ...

    STTR Phase I 2014 Department of Energy
  7. An Equilibrated Micromachined Pressure (EMP) Sensor for Hypersonic Transients

    SBC: RESEARCH SUPPORT INSTRUMENTS, INC.            Topic: N/A

    Research Support Instruments, Inc. (RSI), with the aid of Princeton University, proposes to develop an Equilibrated Micromachined Pressure (EMP) sensor for measuring hypersonic transients with amplitudes < 1 Torr and frequencies of hundreds of kHz.Existing micromachined transducers include capacitive, resistive, or optical techniques. Transducers using silicon membranes and piezoresistive or capa ...

    STTR Phase I 2003 Department of DefenseAir Force
  8. A New Chloride Sweat Test for Cystic Fibrosis Screening

    SBC: PolyChrome Medical, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The CF Quantum(r) sweat test system is a rapid, easily administered, cost effective method to diagnose cystic fibrosis (CF). The CF Quantum(r) patch (Q-patch) uses an ion-exchange reaction to produce a white precipitate which varies in size based on the chloride ion concentration of the sweat sample. Reacting the Q-patch with a chloride-containing solution (i.e ...

    STTR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  9. A New Chloride Sweat Test for Cystic Fibrosis Screening

    SBC: PolyChrome Medical, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The CF Quantum(r) sweat test system is a rapid, easily administered, cost effective method to diagnose cystic fibrosis (CF). The CF Quantum(r) patch (Q-patch) uses an ion-exchange reaction to produce a white precipitate which varies in size based on the chloride ion concentration of the sweat sample. Reacting the Q-patch with a chloride-containing solution (i.e ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  10. A novel Approach for High Rate Production of IR to IR Up-converting Nano-particles

    SBC: UES INC            Topic: AF11BT24

    ABSTRACT: Phosphor materials are currently being utilized in a wide variety of applications. The requirements for phosphors have become more and more stringent with smaller and smaller particles being required. In the Phase I program UES Inc. in collaboration with Penn State University has demonstrated the feasibility of a few approaches for high rate production of high efficiency IR to IR up-con ...

    STTR Phase II 2014 Department of DefenseAir Force
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