Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. A FAP-Activated Proteasome Inhibitor for Killing Solid Tumors

    SBC: ARISAPH PHARMACEUTICALS, INC.            Topic: 102

    DESCRIPTION provided by applicant Cancer is the second leading cause of death after heart disease in the US Chemotherapy is a mainstay of treatment after surgical removal of tumors but the balance of clinical benefit versus disabling or life threatening side effects is often uncertain Genotyping of cancers to identify mutated oncogenes has enabled an era of targeted therapy Drugs targeting ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. A novel Approach for High Rate Production of IR to IR Up-converting Nano-particles

    SBC: UES, Inc.            Topic: AF11BT24

    ABSTRACT: Phosphor materials are currently being utilized in a wide variety of applications. The requirements for phosphors have become more and more stringent with smaller and smaller particles being required. In the Phase I program UES Inc. in collaboration with Penn State University has demonstrated the feasibility of a few approaches for high rate production of high efficiency IR to IR up-con ...

    STTR Phase II 2014 Department of DefenseAir Force
  3. Advanced Optical Diagnostics/Modeling Platform for Plasma Assisted Combustion in Vitiated Air

    SBC: Spectral Energies, LLC            Topic: AF13AT04

    ABSTRACT: Modern gas-turbine engines designs for the next-generation warfighter need to reduce exhaust gas temperatures to reduce effective thermal footprint thereby improving the mission capability. In such situations, high-altitude engine operation is often limited by the overall combustion efficiency, lean flame blow out (LBO) limit, and combustion instabilities that results in narrower opera ...

    STTR Phase I 2014 Department of DefenseAir Force
  4. Advanced Technology for Demilitarization of Plastic Bonded

    SBC: GRADIENT TECHNOLOGY            Topic: N/A

    Gradient Technology in conjunction with Professor M. Hillmyer of the Department of Chemistry at the University of Minnesota proposed to develop advanced technology to recover and convert the explosive and urethane binder found in plastic bonded explosives. This technology provides a unique reclamation, recovery, and reuse opportunity for dramatically reducing the disposal cost of technology munit ...

    STTR Phase I 1998 Department of DefenseAir Force
  5. ANALYSIS OF ATR PROBLEM COMPLEXITY AND SCALABILITY

    SBC: Alaphatech, Inc.            Topic: N/A

    An important problem in the analysis of ATR systems is quantifying the growth of algorithm requirements, such as storage and processing cost, as the input problem l situation in classical complexity analysis, where the notion of input size is well-defined, there does not currenlty exist a clear notion of input size for the ATR problem. In this effort ...

    STTR Phase I 1998 Department of DefenseAir Force
  6. Brain penetrant Hsp90 inhibitors for Alzheimer's disease

    SBC: YUMA THERAPEUTICS CORPORAITON            Topic: NIA

    DESCRIPTION provided by applicant Neurodegeneration in Alzheimerandapos s disease AD may result from deposition of A as plaques in brain tissue However less effort has been made to elucidate the role of tau containing neurofibrillary tangles NFTs in AD Accumulating evidence suggests that tau containing NFTs is an important component in the initiation and progression of AD and other neu ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Coils for Human Whole Body Imaging at 7T

    SBC: LIFE SERVICES L.L.C.            Topic: NIBIB

    DESCRIPTION provided by applicant For this Phase II STTR proposal the investigators plan to develop and commercialize the radiofrequency RF coil technology to make T body MRI possible and to translate this new technology to vastly improve T clinical MRI as well In the Phase I project leading to this proposal all specific aims were accomplished to demonstrate the feasibility of safely an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Compact CMOS-Compatible Optical Transceiver

    SBC: Physical Sciences Inc.            Topic: AF14AT13

    ABSTRACT: Close integration of photonic devices with silicon complementary metal-oxide semiconductor (CMOS) electronics can yield significant performance improvements in many applications. The recent development of novel integrated structures in silicon including waveguides, resonators, and photodetectors will enable dramatic reductions in size, weight, and power for components implementing compl ...

    STTR Phase I 2014 Department of DefenseAir Force
  9. Compound Core Active Multimode Fiber for High-efficiency Fi

    SBC: Altair Center, Llc.            Topic: N/A

    Altair Center proposes to develop a novel and innovative compound-core multimode active flber for high-efficiency fiber laser systems capable to operate in a single-mode regime. The compound multimode core of the fiber is especially designed in such a way to support propagation of a higher order mode exhibiting a sharp peak of its field in the central region of the core. The sharp-peak mode extrac ...

    STTR Phase I 1998 Department of DefenseAir Force
  10. CONDUCTIVE POLYMER-SILVER NANOCOMPOSITE WIRES FOR NSAF SATE

    SBC: Triton Systems, Inc.            Topic: N/A

    Triton Systems, in partnership with Prof. William Moser of Worcester Polytechnic Institute (WPI) proposes to develop a new lightwright, high strength, electrical signal distribution wire for satellites and aircraft based on a new unique conductive polymer, silver nanoparticle (CP-Ag) composit material. The CP-Ag Kevlar composite wire will have a density of less than l.9 g/cc (compared to 10.5 g/ ...

    STTR Phase I 1998 Department of DefenseAir Force
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