Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. A FAP-Activated Proteasome Inhibitor for Killing Solid Tumors

    SBC: ARISAPH PHARMACEUTICALS, INC.            Topic: 102

    DESCRIPTION provided by applicant Cancer is the second leading cause of death after heart disease in the US Chemotherapy is a mainstay of treatment after surgical removal of tumors but the balance of clinical benefit versus disabling or life threatening side effects is often uncertain Genotyping of cancers to identify mutated oncogenes has enabled an era of targeted therapy Drugs targeting ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. A novel Approach for High Rate Production of IR to IR Up-converting Nano-particles

    SBC: UES, Inc.            Topic: AF11BT24

    ABSTRACT: Phosphor materials are currently being utilized in a wide variety of applications. The requirements for phosphors have become more and more stringent with smaller and smaller particles being required. In the Phase I program UES Inc. in collaboration with Penn State University has demonstrated the feasibility of a few approaches for high rate production of high efficiency IR to IR up-con ...

    STTR Phase II 2014 Department of DefenseAir Force
  3. Adaptive multi-mode photodetector and focal plane array

    SBC: APPLIED NANOFEMTO TECHNOLOGIES LLC            Topic: AF09BT37

    Multi-modal (including spatial, spectral and polarimetric) photodetectors and focal plane arrays (FPA) can dramatically enhance the target detection, tracking and identification capability of a battle field sensing system. Most existing multi-spectral polarimetric sensing systems employ dispersive optics (gratings or prisms), or external polarizer technologies to obtain spectral and polarimetric c ...

    STTR Phase I 2010 Department of DefenseAir Force
  4. Advanced Auditory Modeling for Acoustic Analysis

    SBC: BIOMIMETIC SYSTEMS, INC.            Topic: AF09BT12

    The human auditory system out-performs all current machine-based systems for analyzing and interpreting real world acoustic environments. Central to that human performance is the method of auditory scene analysis used by listeners and the mechanisms that allow creation of auditory objects. BioMimetic Systems has implemented real-time biomimetic algorithms in embedded hardware based on the ‘what ...

    STTR Phase I 2010 Department of DefenseAir Force
  5. Advanced Optical Diagnostics/Modeling Platform for Plasma Assisted Combustion in Vitiated Air

    SBC: Spectral Energies, LLC            Topic: AF13AT04

    ABSTRACT: Modern gas-turbine engines designs for the next-generation warfighter need to reduce exhaust gas temperatures to reduce effective thermal footprint thereby improving the mission capability. In such situations, high-altitude engine operation is often limited by the overall combustion efficiency, lean flame blow out (LBO) limit, and combustion instabilities that results in narrower opera ...

    STTR Phase I 2014 Department of DefenseAir Force
  6. Aerosol Plasmon-Enhanced Laser Desorption Ionization

    SBC: Aerodyne Research, Inc.            Topic: AF09BT34

    Aerodyne Research, Inc. (ARI) and The University of Massachusetts at Amherst will collaborate to develop a novel technique for efficient mass spectrometric analysis of high molecular weight analytes such as proteins and polymers. Laser desorption and ionization with minimal analyte fragmentaton will be carried out on metal nanoparticle substrates in a particle beam sampled by Aerodyne’s proprie ...

    STTR Phase I 2010 Department of DefenseAir Force
  7. Auditory Cues based Speech Enhancement Processing Technology (ACSEPT)

    SBC: MAYFLOWER COMMUNICATIONS COMPANY, INC.            Topic: AF09BT12

    Mayflower Communications has partnered with the Boston University Hearing Research Center to propose novel techniques for speech enhancement in reverberant environment based on advanced auditory modeling of higher-level processing in the human auditory brain. Speech enhancement or noise suppression has been an area of active research for well over three decades. State-of-the-art single-microphone ...

    STTR Phase I 2010 Department of DefenseAir Force
  8. Brain penetrant Hsp90 inhibitors for Alzheimer's disease

    SBC: YUMA THERAPEUTICS CORPORAITON            Topic: NIA

    DESCRIPTION provided by applicant Neurodegeneration in Alzheimerandapos s disease AD may result from deposition of A as plaques in brain tissue However less effort has been made to elucidate the role of tau containing neurofibrillary tangles NFTs in AD Accumulating evidence suggests that tau containing NFTs is an important component in the initiation and progression of AD and other neu ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Coils for Human Whole Body Imaging at 7T

    SBC: LIFE SERVICES L.L.C.            Topic: NIBIB

    DESCRIPTION provided by applicant For this Phase II STTR proposal the investigators plan to develop and commercialize the radiofrequency RF coil technology to make T body MRI possible and to translate this new technology to vastly improve T clinical MRI as well In the Phase I project leading to this proposal all specific aims were accomplished to demonstrate the feasibility of safely an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Compact CMOS-Compatible Optical Transceiver

    SBC: Physical Sciences Inc.            Topic: AF14AT13

    ABSTRACT: Close integration of photonic devices with silicon complementary metal-oxide semiconductor (CMOS) electronics can yield significant performance improvements in many applications. The recent development of novel integrated structures in silicon including waveguides, resonators, and photodetectors will enable dramatic reductions in size, weight, and power for components implementing compl ...

    STTR Phase I 2014 Department of DefenseAir Force
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