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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Access to Exercise Stress Testing for Elderly Native Americans in Remote Locations

    SBC: ADVANCED MEDICAL ELECTRONICS CORP            Topic: N

    DESCRIPTION provided by applicant Heart disease is the leading cause of death among elderly American Indians and Alaska Natives Heart disease death rates for elderly American Indians at per are percent higher than average in the total U S population Most elderly Native Americans live in remote locations and lack transportation to healthcare facilities This is a key barrie ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. A FAP-Activated Proteasome Inhibitor for Killing Solid Tumors

    SBC: ARISAPH PHARMACEUTICALS, INC.            Topic: 102

    DESCRIPTION provided by applicant Cancer is the second leading cause of death after heart disease in the US Chemotherapy is a mainstay of treatment after surgical removal of tumors but the balance of clinical benefit versus disabling or life threatening side effects is often uncertain Genotyping of cancers to identify mutated oncogenes has enabled an era of targeted therapy Drugs targeting ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. A New MicroRNA-1291 Replacement Therapy for Pancreatic Cancer Disease

    SBC: MIRNA THERAPEUTICS, INC.            Topic: NIAAA

    DESCRIPTION (provided by applicant): Pancreatic cancer is the fourth leading cause of cancer-related death in the United States. There is a clear need for more effective therapies to treat deadly pancreatic cancer disease. MicroRNAs (miRNA or miR) are a large group of short, noncoding RNAs that control posttranscriptional gene expression in human cells, and there is increasing evidence for the exi ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. A novel 3D cell culture human uterine contractility assay for high-throughput scr

    SBC: CHEMOSEN3D INC            Topic: NICHD

    DESCRIPTION (provided by applicant): Several disorders in reproductive medicine are results of changes in smooth muscle contractile activity. Increased myometrial contraction can lead to preterm labor, which affects 12% of the US population. However, the mechanisms involved in the transition from uterine quiescence to contractility at the onset of labor are not well-known. As a result, the managem ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. A novel drug detection assay using fluorescent biosensor technology

    SBC: GLSynthesis Inc.            Topic: 300

    DESCRIPTION provided by applicant This phase project has as its overall objectives to design engineer optimize and implement a novel genetically encoded fluorescent drug sensor FDS based on F rster Resonance Energy Transfer FRET by exploiting conformational rearrangements induced by drug interactions with human serum albumin SA SA is uniquely suited for a general drug sensor beca ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. A novel racial disparity marker for risk prediction in triple negative breast cancer patients

    SBC: NOVAZOI THERANOSTICS            Topic: NIMHD

    DESCRIPTION provided by applicant Breast cancers in African American AA women are characterized by earlier onset higher aggressiveness more extensive metastases and increased mortality rates compared to those in European American EA women This breast cancer related health disparity is partly due to the fact that AA women are more likely than EA women to develop a particularly aggressive ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. A Novel Technology to Produce Yb:Sr-FAP Transparent Laser Host Ceramics in Non-Isotropic Materials

    SBC: TEXAS BIOCHEMICALS INC            Topic: AF14AT26

    ABSTRACT: To fabricate transparent ceramics composed of anisotropic laser gain media, the crystal orientations of micro-domains should be aligned identically. Current method involve application of high magnetic field. Texas Biochemicals Inc. recently developed a novel technology to produce faceted hexagonal prism c axis oriented Yb: Sr-FAP [Yb: Sr5(PO4)3F nanocrystallites and sintered into transp ...

    STTR Phase I 2014 Department of DefenseAir Force
  8. APPSPIRE: expanding the reach of an innovative tobacco control program for youth

    SBC: Radiant Creative Group, LLC            Topic: NIDA

    DESCRIPTIONprovided by applicantMobile phone technology offers a variety of opportunities for innovative approaches to health communication and interventionThese opportunities have been amplified by the emergence of next generation smartphone devices that are capable of rich multimedia and sophisticated interactivitySmartphone based programs can be integrated seamlessly into a userandapos s daily ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  9. A Range Segment Upgrade for Air Force Satellite Control Network with Smart Antennas and Cognitive Satellite Radios

    SBC: INFOBEYOND TECHNOLOGY LLC            Topic: AF14AT16

    ABSTRACT: A range segment upgrade for Air Force satellite control network (AFSCN) will significantly improve system effectiveness via spectrum sharing and seamless interoperation. However, the upgraded system requires new capabilities such as real-time and accurate RF interference detection and mitigation, array antenna backlobe/sidelobe suppressions, accurate performance degradation prediction, ...

    STTR Phase I 2015 Department of DefenseAir Force
  10. A smart needle guide template for MRI-guided transperineal prostate biopsy

    SBC: PHYSICAL SCIENCES INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Physical Sciences Inc. (PSI) and the Surgical Navigation and Robotics Laboratory (SNR) at Brigham and Women's Hospital (BWH) propose to develop and test a Smart Template to guide transperineal targeted prostate biopsiesand subsequent therapy under magnetic resonance imaging (MRI). The project aims to solve the problem of poor diagnostic yield in prostate b ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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