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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. A FAP-Activated Proteasome Inhibitor for Killing Solid Tumors

    SBC: ARISAPH PHARMACEUTICALS, INC.            Topic: 102

    DESCRIPTION provided by applicant Cancer is the second leading cause of death after heart disease in the US Chemotherapy is a mainstay of treatment after surgical removal of tumors but the balance of clinical benefit versus disabling or life threatening side effects is often uncertain Genotyping of cancers to identify mutated oncogenes has enabled an era of targeted therapy Drugs targeting ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. A Framework for Modeling and Analyzing Complex Distributed Systems

    SBC: VEROMODO, INC.            Topic: AF04T023

    Summary and intellectual merit. This Small Business Technology Transfer Phase I project will develop a modeling language and computational support tools for specifying, analyzing, and verifying complex distributed system designs. The overall modeling and analysis framework will provide an integrated suite of tools and methods ultimately leading to qualitative improvements in the design ...

    STTR Phase I 2004 Department of DefenseAir Force
  3. Active Silicon Nanophotonics based on Photonic Crystal with Quantum Dots

    SBC: Altair Center, Llc.            Topic: AF04T013

    ALTAIR Center in cooperation with University of Rochester proposes to develop a new class of active nanophotonic devices based on quantum dots embedded into photonic crystal microstructures fabricated in silicon-on-insulator waveguides. Due to extremely strong nonlinear optical and electro-optical properties and extremely short switching times, the silicon-based photonic crystal microstructures wi ...

    STTR Phase I 2004 Department of DefenseAir Force
  4. Advanced Composites with Nanoscale Reinforcement

    SBC: Nanolab, Inc            Topic: AF04T020

    Advanced fiber composites are fabricated by automated 3D weaving and braiding processes. These weaving processes use tows of micron diameter fibers, to create preforms for resin infiltration. The interaction between the resin matrix and the fibers can be potentially increased by creating nanoscale features on the carbon fibers. NanoLab is expert in the synthesis of carbon nanotubes and their app ...

    STTR Phase I 2004 Department of DefenseAir Force
  5. Automated Diagnosis of Usability Problems Using Statistical Computational Methods

    SBC: APTIMA, INC.            Topic: AF03T001

    Poorly designed software and hardware systems are inconvenient at best; at worst, they are deadly. Usability evaluation techniques are designed to detect the potential for disasters and inefficiencies in poorly designed software. However, usability analyses are prone to failure due to conflicting usability frameworks, incomplete usability reports, and inadequate analysis tools. Aptima and the Ce ...

    STTR Phase II 2004 Department of DefenseAir Force
  6. Brain penetrant Hsp90 inhibitors for Alzheimer's disease

    SBC: YUMA THERAPEUTICS CORPORAITON            Topic: NIA

    DESCRIPTION provided by applicant Neurodegeneration in Alzheimerandapos s disease AD may result from deposition of A as plaques in brain tissue However less effort has been made to elucidate the role of tau containing neurofibrillary tangles NFTs in AD Accumulating evidence suggests that tau containing NFTs is an important component in the initiation and progression of AD and other neu ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Coils for Human Whole Body Imaging at 7T

    SBC: LIFE SERVICES L.L.C.            Topic: NIBIB

    DESCRIPTION provided by applicant For this Phase II STTR proposal the investigators plan to develop and commercialize the radiofrequency RF coil technology to make T body MRI possible and to translate this new technology to vastly improve T clinical MRI as well In the Phase I project leading to this proposal all specific aims were accomplished to demonstrate the feasibility of safely an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Compact CMOS-Compatible Optical Transceiver

    SBC: Physical Sciences Inc.            Topic: AF14AT13

    ABSTRACT: Close integration of photonic devices with silicon complementary metal-oxide semiconductor (CMOS) electronics can yield significant performance improvements in many applications. The recent development of novel integrated structures in silicon including waveguides, resonators, and photodetectors will enable dramatic reductions in size, weight, and power for components implementing compl ...

    STTR Phase I 2014 Department of DefenseAir Force
  9. Control Center Fatigue Monitoring System

    SBC: FOSTER-MILLER, INC.            Topic: AF04T007

    Abstract: The nature of military operations requires around-the-clock operation. Consequently military personnel responsible for overseeing routine as well as battlefield activity must work at times outside the weekday, daytime hours common in many other occupations. Given the serious consequences for US defense strategy and the safety of US servicemen and women, it is imperative that control ce ...

    STTR Phase I 2004 Department of DefenseAir Force
  10. Cooperative Search, Acquisition and Tracking by UAV Teams

    SBC: ALPHATECH, INC.            Topic: AF04T011

    ALPHATECH and MIT propose to extend existing real-time mission manager, path planning, and video tracking technologies developed under DARPA, AFOSR, and AFRL programs to solve the Cooperative Search Acquisition and Track (CSAT) problem for multiple moving targets. This CSAT mission presents difficult challenges combining different types of tasking: area search, periodic track maintenance, focuse ...

    STTR Phase I 2004 Department of DefenseAir Force

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