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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. A FAP-Activated Proteasome Inhibitor for Killing Solid Tumors

    SBC: ARISAPH PHARMACEUTICALS, INC.            Topic: 102

    DESCRIPTION provided by applicant Cancer is the second leading cause of death after heart disease in the US Chemotherapy is a mainstay of treatment after surgical removal of tumors but the balance of clinical benefit versus disabling or life threatening side effects is often uncertain Genotyping of cancers to identify mutated oncogenes has enabled an era of targeted therapy Drugs targeting ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. An Integrated Software Package for the Design and Simulation of Waveguides Fabricated from Omnidirectionally Reflective Composite Dielectric Materials

    SBC: Omniguide Communications, Inc.            Topic: AF02T015

    An OmniGuide fiber is a hollow-core fiber which employs a dielectric omnidirectional mirror to keep light confined to its core. These novel fibers are ideally suited for ultra-low loss optical transmission and for flexible delivery of high power lasers. Prior to and during our Phase I effort, we have developed a wide range of tools to simulate the performance of OmniGuide fibers and related stru ...

    STTR Phase II 2005 Department of DefenseAir Force
  3. Application of Cortical Processing Theory to Acoustical Analysis

    SBC: Sensimetrics Corporation            Topic: AF03T006

    The goal of this STTR program is to formulate a template-matching operation, with perception-related rules of integration over time and frequency at its core, in the context of human perception of degraded speech. In Phase I we focused on implementing signal processing principles realized by the auditory periphery in providing the observed graceful degradation of human performance in noise, a prer ...

    STTR Phase II 2005 Department of DefenseAir Force
  4. Brain penetrant Hsp90 inhibitors for Alzheimer's disease

    SBC: YUMA THERAPEUTICS CORPORAITON            Topic: NIA

    DESCRIPTION provided by applicant Neurodegeneration in Alzheimerandapos s disease AD may result from deposition of A as plaques in brain tissue However less effort has been made to elucidate the role of tau containing neurofibrillary tangles NFTs in AD Accumulating evidence suggests that tau containing NFTs is an important component in the initiation and progression of AD and other neu ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Coils for Human Whole Body Imaging at 7T

    SBC: LIFE SERVICES L.L.C.            Topic: NIBIB

    DESCRIPTION provided by applicant For this Phase II STTR proposal the investigators plan to develop and commercialize the radiofrequency RF coil technology to make T body MRI possible and to translate this new technology to vastly improve T clinical MRI as well In the Phase I project leading to this proposal all specific aims were accomplished to demonstrate the feasibility of safely an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Coil Simulator for AC Conductors

    SBC: AMERICAN SUPERCONDUCTOR CORPORATION            Topic: AF04T002

    This STTR Project addresses stability issues in Second Generation High Temperature Super- conductor (2G HTS) wire. It explores novel ways to address and characterize 2G HTS stability, in particular when used under ac conditions. In the Phase I novel components for increased stability were explored. Stability of various conductors was tested. A so-called "Coil Simulator” was designed. In the Phas ...

    STTR Phase II 2005 Department of DefenseAir Force
  7. Coil Simulators for AC Conductors

    SBC: AMERICAN SUPERCONDUCTOR CORPORATION            Topic: AF04T002

    This STTR Project addresses stability issues in Second Generation High Temperature Superconductor (2G HTS) wire and will test novel components for increased stability and measurement techniques to evaluate stability at a wide range of conditions, in particular for demanding military AC HTS applications. Wire fabrication at AMSC and testing experiments at FSU will focus on AC stability and quench ...

    STTR Phase I 2005 Department of DefenseAir Force
  8. Compact CMOS-Compatible Optical Transceiver

    SBC: Physical Sciences Inc.            Topic: AF14AT13

    ABSTRACT: Close integration of photonic devices with silicon complementary metal-oxide semiconductor (CMOS) electronics can yield significant performance improvements in many applications. The recent development of novel integrated structures in silicon including waveguides, resonators, and photodetectors will enable dramatic reductions in size, weight, and power for components implementing compl ...

    STTR Phase I 2014 Department of DefenseAir Force
  9. Compact Induced Current Hall Thruster

    SBC: Busek Co., Inc.            Topic: AF03T016

    This Phase II STTR program is proposed to investigate a new kind of electric thruster, an inductively-driven Hall thruster. In contrast to conventional Hall thrusters, this device has the big advantage of needing no cathode. We expect it to be more efficient, because the inefficiencies from electrode voltage drops have been eliminated, and it can also be smaller, because the cathode that cannot ...

    STTR Phase II 2005 Department of DefenseAir Force
  10. Computational Prediction of Kinetic Rate Constants

    SBC: Spectral Sciences, Inc.            Topic: AF05T010

    A core component of aerospace manufacturing is based on cutting-edge materials used in extreme environments. Chemical kinetics models are vital for interpreting experimental measurements and predicting the behavior of these complex systems. For many applications, the reaction rates for all required chemical processes are unknown. We propose a versatile user-friendly computational package for ca ...

    STTR Phase I 2005 Department of DefenseAir Force
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